(Q38765872)

6 September 2017

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title

High-throughput screening and selection of mammalian cells for enhanced protein production (English)

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6 September 2017

Nicole Borth

4

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Michael J Betenbaugh

6

object named as

Michael J Betenbaugh

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6 September 2017

Joseph J Priola

1

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6 September 2017

Nathan Calzadilla

2

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6 September 2017

Martina Baumann

3

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6 September 2017

Christopher G Tate

5

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6 September 2017

publication date

8 June 2016

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6 September 2017

published in

Biotechnology Journal

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6 September 2017

volume

11

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6 September 2017

issue

7

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6 September 2017

page(s)

853-865

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Beyond Borders 2014 - Overview of the Biotechnology Landscape

6 September 2017

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21 January 2018

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Optimization of sorting conditions for the selection of stable, high-producing mammalian cell lines

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A rapid method for viable cell titration and clone production with HeLa cells in tissue culture: the use of X-irradiated cells to supply conditioning factors

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Selection of high-producing CHO cells using NPT selection marker with reduced enzyme activity.

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Improved recombinant protein yield using a codon deoptimized DHFR selectable marker in a CHEF1 expression plasmid

21 January 2018

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Evaluating the influence of selection markers on obtaining selected pools and stable cell lines in human cells

21 January 2018

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The isolation of CHO cells with a site conferring a high and reproducible transgene amplification rate.

21 January 2018

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Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Novel membrane-bound reporter molecule for sorting high producer cells by flow cytometry

21 January 2018

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High-throughput sorting of the highest producing cell via a transiently protein-anchored system

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201500579

Primary Bioassay of Human Myeloma Stem Cells

21 January 2018

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A simple, single-step technique for selecting and cloning hybridomas for the production of monoclonal antibodies

21 January 2018

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Fluorescent labeling in semi-solid medium for selection of mammalian cells secreting high-levels of recombinant proteins

21 January 2018

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High-throughput ClonePix FL analysis of mAb-expressing clones using the UCOE expression system.

21 January 2018

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21 January 2018

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21 January 2018

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Automated in situ measurement of cell-specific antibody secretion and laser-mediated purification for rapid cloning of highly-secreting producers

21 January 2018

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Rapid selection of single cells with high antibody production rates by microwell array.

21 January 2018

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A microengraving method for rapid selection of single cells producing antigen-specific antibodies

21 January 2018

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A rapid and efficient single-cell manipulation method for screening antigen-specific antibody-secreting cells from human peripheral blood.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201500579

Array-based analysis of secreted glycoproteins for rapid selection of a single cell producing a glycoprotein with desired glycosylation.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201500579

Profiling antibody responses by multiparametric analysis of primary B cells.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201500579

Automation of cell line development

21 January 2018

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21 January 2018

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21 January 2018

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Antibody discovery via multiplexed single cell characterization.

21 January 2018

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A high-throughput automated platform for the development of manufacturing cell lines for protein therapeutics

21 January 2018

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21 January 2018

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Strategies for selecting recombinant CHO cell lines for cGMP manufacturing: realizing the potential in bioreactors

21 January 2018

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21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201500579

Advances in Mammalian cell line development technologies for recombinant protein production

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201500579

Challenges in industrial fermentation technology research.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201500579

A strategy for clone selection under different production conditions

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201500579

A review of advanced small-scale parallel bioreactor technology for accelerated process development: current state and future need

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201500579

Twenty-four well plate miniature bioreactor system as a scale-down model for cell culture process development

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201500579

Twenty-four-well plate miniature bioreactor high-throughput system: assessment for microbial cultivations.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201500579

Microfluidic biolector-microfluidic bioprocess control in microtiter plates.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201500579

A predictive high-throughput scale-down model of monoclonal antibody production in CHO cells.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201500579

High-throughput miniaturized bioreactors for cell culture process development: reproducibility, scalability, and control

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201500579

Advanced microscale bioreactor system: a representative scale-down model for bench-top bioreactors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201500579

Rapid high-throughput characterisation, classification and selection of recombinant mammalian cell line phenotypes using intact cell MALDI-ToF mass spectrometry fingerprinting and PLS-DA modelling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201500579

21 January 2018

Identifiers

DOI

10.1002/BIOT.201500579

1 reference

6 September 2017

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