(Q38792900)

6 September 2017

title

Droplet-based microfluidics in drug discovery, transcriptomics and high-throughput molecular genetics (English)

1 reference

6 September 2017

0 references

0 references

1 reference

1 reference

Christoph A Merten

4

0 references

author name string

Nachiket Shembekar

series ordinal

1

1 reference

6 September 2017

Chawaree Chaipan

series ordinal

2

1 reference

6 September 2017

Ramesh Utharala

series ordinal

3

1 reference

6 September 2017

language of work or name

English

0 references

publication date

30 March 2016

1 reference

6 September 2017

number of pages

18

1 reference

based on heuristic

inferred from page(s)

published in

Lab on a Chip

1 reference

6 September 2017

volume

16

1 reference

6 September 2017

issue

8

1 reference

6 September 2017

page(s)

1314-1331

1 reference

Microfluidic single-cell analysis for systems immunology

6 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Miniaturization and parallelization of biological and chemical assays in microfluidic devices

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

21 January 2018

Digital microfluidics

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Recent developments in microfluidic large scale integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Microdroplets in microfluidics: an evolving platform for discoveries in chemistry and biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Droplet microfluidics for high-throughput biological assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Geometrically mediated breakup of drops in microfluidic devices

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

On-chip single-copy real-time reverse-transcription PCR in isolated picoliter droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Droplet-Based Microfluidic Platforms for the Encapsulation and Screening of Mammalian Cells and Multicellular Organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

New family of fluorinated polymer chips for droplet and organic solvent microfluidics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Dynamic Pattern Formation in a Vesicle-Generating Microfluidic Device

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Formation of dispersions using “flow focusing” in microchannels

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

High-performance flow-focusing geometry for spontaneous generation of monodispersed droplets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Biocompatible surfactants for water-in-fluorocarbon emulsions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Surfactants in droplet-based microfluidics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Quantitative detection of protein expression in single cells using droplet microfluidics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

High-yield cell ordering and deterministic cell-in-droplet encapsulation using Dean flow in a curved microchannel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Drop-based microfluidic devices for encapsulation of single cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Droplet microfluidic technology for single-cell high-throughput screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

1-Million droplet array with wide-field fluorescence imaging for digital PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Droplet-based microfluidic systems for high-throughput single DNA molecule isothermal amplification and analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Simultaneous determination of gene expression and enzymatic activity in individual bacterial cells in microdroplet compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Efficient cell pairing in droplets using dual-color sorting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Microfluidic systems for chemical kinetics that rely on chaotic mixing in droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Experimental test of scaling of mixing by chaotic advection in droplets moving through microfluidic channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Nonviral gene vector formation in monodispersed picolitre incubator for consistent gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Reliable microfluidic on-chip incubation of droplets in delay-lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Functional single-cell hybridoma screening using droplet-based microfluidics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

A fast and efficient microfluidic system for highly selective one-to-one droplet fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Microfluidic high-throughput encapsulation and hydrodynamic self-sorting of single cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Design of microfluidic channel geometries for the control of droplet volume, chemical concentration, and sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Pillar-induced droplet merging in microfluidic circuits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

High-throughput injection with microfluidics using picoinjectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

High-throughput DNA droplet assays using picoliter reactor volumes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Ultrafast Surface Enhanced Resonance Raman Scattering Detection in Droplet-Based Microfluidic Systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Studies on the micropolarities of bmimBF4/TX-100/toluene ionic liquid microemulsions and their behaviors characterized by UV-visible spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Compartmentalization of chemically separated components into droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Droplet-based compartmentalization of chemically separated components in two-dimensional separations

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Coupling microdroplet microreactors with mass spectrometry: reading the contents of single droplets online.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Microgram-scale testing of reaction conditions in solution using nanoliter plugs in microfluidics with detection by MALDI-MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Sampling and electrophoretic analysis of segmented flow streams using virtual walls in a microfluidic device

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Marker-specific sorting of rare cells using dielectrophoresis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

A microfabricated fluorescence-activated cell sorter

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Optofluidic cell selection from complex microbial communities for single-genome analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Sorting drops and cells with acoustics: acoustic microfluidic fluorescence-activated cell sorter

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Specific sorting of single bacterial cells with microfabricated fluorescence-activated cell sorting and tyramide signal amplification fluorescence in situ hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

An integrated microfluidic system for reaction, high-sensitivity detection, and sorting of fluorescent cells and particles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Accurate microfluidic sorting of droplets at 30 kHz.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Controlling molecular transport in minimal emulsions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Passive antibody therapy for infectious diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Improving the efficacy of antibody-based cancer therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

IgG1 protects against renal disease in a mouse model of cryoglobulinaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Antibody therapeutics in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Therapeutic antibodies for autoimmunity and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

The therapeutic monoclonal antibody market

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Isolation of antigen-specific B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Single-cell analysis and sorting using droplet-based microfluidics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Homogeneous Cell- and Bead-Based Assays for High Throughput Screening Using Fluorometric Microvolume Assay Technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Droplet-based microfluidic platforms for single T cell secretion analysis of IL-10 cytokine

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Interfacing microwells with nanoliter compartments: a sampler generating high-resolution concentration gradients for quantitative biochemical analyses in droplets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

An automated two-phase microfluidic system for kinetic analyses and the screening of compound libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Automated microdroplet platform for sample manipulation and polymerase chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Microfluidic bead suspension hopper

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

High-resolution dose-response screening using droplet-based microfluidics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Systematic discovery of multicomponent therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Drug repositioning: identifying and developing new uses for existing drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

21 January 2018

New uses for old drugs

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

High-throughput screening in drug metabolism and pharmacokinetic support of drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

The rise, fall and reinvention of combinatorial chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Application of combinatorial chemistry science on modern drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Microfluidic platform for combinatorial synthesis in picolitre droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

A barcode-free combinatorial screening platform for matrix metalloproteinase screening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Nanoliter plates--versatile tools for the screening of split-and-mix libraries on-bead and off-bead.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

On-chip, real-time, single-copy polymerase chain reaction in picoliter droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Analysis of gene expression at the single-cell level using microdroplet-based microfluidic technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Digital PCR strategies in the development and analysis of molecular biomarkers for personalized medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Microfluidic digital PCR enables multigene analysis of individual environmental bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Quantitative and sensitive detection of rare mutations using droplet-based microfluidics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Multiplex picodroplet digital PCR to detect KRAS mutations in circulating DNA from the plasma of colorectal cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Single molecule quantitation and sequencing of rare translocations using microfluidic nested digital PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

A microfluidic droplet digital PCR for simultaneous detection of pathogenic Escherichia coli O157 and Listeria monocytogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Agarose droplet microfluidics for highly parallel and efficient single molecule emulsion PCR

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Single-cell forensic short tandem repeat typing within microfluidic droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

DNA sequence analysis with droplet-based microfluidics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Microfluidic droplet enrichment for targeted sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

High-throughput single copy DNA amplification and cell analysis in engineered nanoliter droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Single-cell genomic sequencing using Multiple Displacement Amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Uniform and accurate single-cell sequencing based on emulsion whole-genome amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Enhanced sequencing coverage with digital droplet multiple displacement amplification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Identification and genetic analysis of cancer cells with PCR-activated cell sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

PCR-activated cell sorting for cultivation-free enrichment and sequencing of rare microbes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Ultrahigh-throughput Mammalian single-cell reverse-transcriptase polymerase chain reaction in microfluidic drops

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Expression profiling. Combinatorial labeling of single cells for gene expression cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

In-depth determination and analysis of the human paired heavy- and light-chain antibody repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Artifact-Free Quantification and Sequencing of Rare Recombinant Viruses by Using Drop-Based Microfluidics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

Isolation and Analysis of Rare Norovirus Recombinants from Coinfected Mice Using Drop-Based Microfluidics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6LC00249H

21 January 2018

Identifiers

DOI

10.1039/C6LC00249H

1 reference

6 September 2017

1 reference