(Q38809316)

English

Rapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1-Transfected Human Embryonic Kidney 293 Cells.

scientific article published on 23 December 2015

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scholarly article

1 reference

Europe PubMed Central

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3 March 2020

Rapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1-Transfected Human Embryonic Kidney 293 Cells (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26700958%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

based on heuristic

inferred from title

4

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3 March 2020

Dennis O. Scott

7

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3 March 2020

author name string

Huan-Chieh Chien

1

1 reference

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3 March 2020

Arik A Zur

2

1 reference

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3 March 2020

Tristan S Maurer

3

1 reference

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3 March 2020

John Tolsma

5

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3 March 2020

Paul Jasper

6

1 reference

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3 March 2020

Kathleen M Giacomini

8

1 reference

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3 March 2020

publication date

23 December 2015

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3 March 2020

Drug Metabolism and Disposition

1 reference

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3 March 2020

44

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3 March 2020

3

1 reference

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3 March 2020

356-364

1 reference

Europe PubMed Central

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3 March 2020

Intracellular concentrations determine the cytotoxicity of adefovir, cidofovir and tenofovir

1 reference

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1 reference

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OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin.

1 reference

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Ischemia/Reperfusion-inducible protein modulates the function of organic cation transporter 1 and multidrug and toxin extrusion 1.

1 reference

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31 August 2018

Rapid measurement of intracellular unbound drug concentrations.

1 reference

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31 August 2018

Intracellular drug concentrations and transporters: measurement, modeling, and implications for the liver

1 reference

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Detection of statin cytotoxicity is increased in cells expressing the OATP1B1 transporter

1 reference

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31 August 2018

Intracellular drug concentrations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6047207

31 August 2018

Cellular and molecular mechanisms of metformin: an overview

1 reference

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31 August 2018

Brain mitochondrial drug delivery: influence of drug physicochemical properties

1 reference

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Measuring steady-state and dynamic endoplasmic reticulum and Golgi Zn2+ with genetically encoded sensors

1 reference

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Optimizing optical flow cytometry for cell volume-based sorting and analysis

1 reference

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31 August 2018

Membrane transporters in drug development

1 reference

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31 August 2018

Pharmacokinetics of metformin during pregnancy

1 reference

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31 August 2018

The effects of genetic polymorphisms in the organic cation transporters OCT1, OCT2, and OCT3 on the renal clearance of metformin.

1 reference

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31 August 2018

Methodological aspects of measuring absolute values of membrane potential in human cells by flow cytometry

1 reference

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31 August 2018

Quantitative modeling of selective lysosomal targeting for drug design

1 reference

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31 August 2018

Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6047207

31 August 2018

How many drug targets are there?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6047207

31 August 2018

Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6047207

31 August 2018

Intraluminal calcium as a primary regulator of endoplasmic reticulum function

1 reference

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A predictive model for the selective accumulation of chemicals in tumor cells.

1 reference

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Progress towards prediction of human pharmacokinetic parameters from in vitro technologies.

1 reference

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31 August 2018

Involvement of organic cation transporter 1 in hepatic and intestinal distribution of metformin

1 reference

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31 August 2018

Usefulness and limitation of DiBAC4(3), a voltage-sensitive fluorescent dye, for the measurement of membrane potentials regulated by recombinant large conductance Ca2+-activated K+ channels in HEK293 cells

1 reference

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KCNQ4 channels expressed in mammalian cells: functional characteristics and pharmacology

1 reference

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1 reference

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31 August 2018

K+-selective channel from sarcoplasmic reticulum of split lobster muscle fibers

1 reference

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31 August 2018

Cimetidine transport in isolated luminal membrane vesicles from rabbit kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/26700958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of intracellular volume in monolayers of cultured cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/26700958

12 December 2020

based on heuristic

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Identifiers

10.1124/DMD.115.066647

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26700958%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26700958%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26700958%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

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