(Q38811785)

6 September 2017

The role of Akt (protein kinase B) and protein kinase C in ischemia-reperfusion injury (English)

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6 September 2017

1 reference

Ethan Y Zhao

1

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6 September 2017

Aslan Efendizade

series ordinal

2

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6 September 2017

Lipeng Cai

series ordinal

3

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6 September 2017

Yuchuan Ding

series ordinal

4

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6 September 2017

19 April 2016

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6 September 2017

Neurological Research

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6 September 2017

38

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6 September 2017

4

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6 September 2017

301-308

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Neuroprotection for ischemic stroke: past, present and future

6 September 2017

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Neuroprotection for stroke: current status and future perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Neuroprotection for ischemic stroke: two decades of success and failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

The complexity of neurobiological processes in acute ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

The science of stroke: mechanisms in search of treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

State and activity of protein kinase C in postischemic reperfused liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Induction and subcellular localization of protein kinase C isozymes following renal ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

The role of protein kinase C in cerebral ischemic and reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

The protein kinase C family for neuronal signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Cardioprotective mechanisms of PKC isozyme-selective activators and inhibitors in the treatment of ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Ischemic preconditioning: from adenosine receptor to KATP channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Cell-specific role for epsilon- and betaI-protein kinase C isozymes in protecting cortical neurons and astrocytes from ischemia-like injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Protein kinase C-epsilon is involved in the adenosine-activated signal transduction pathway conferring protection against ischemia-reperfusion injury in primary rat neuronal cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Mitochondrial PKCepsilon and MAPK form signaling modules in the murine heart: enhanced mitochondrial PKCepsilon-MAPK interactions and differential MAPK activation in PKCepsilon-induced cardioprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Mitochondrial ATP-sensitive potassium channel activation protects cerebellar granule neurons from apoptosis induced by oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Opening of mitochondrial K(ATP) channel occurs downstream of PKC-epsilon activation in the mechanism of preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Differential subcellular redistribution of protein kinase C isozymes in the rat hippocampus induced by kainic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Down-regulation of protein kinase C protects cerebellar granule neurons in primary culture from glutamate-induced neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Induction and activation of protein kinase C delta in hippocampus and cortex after kainic acid treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Isoform-specific membrane translocation of protein kinase C after ischemic preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Inhibitors of protein kinase C prevent the toxicity of glutamate in primary neuronal cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Prevention of NMDA-induced death of cortical neurons by inhibition of protein kinase Czeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Protein kinase C gamma (PKC gamma): function of neuron specific isotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Perspectives on reperfusion-induced damage in rodent models of experimental focal ischemia and role of gamma-protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Convergence of PKC-dependent kinase signal cascades on NMDA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Characterization of protein kinase A and protein kinase C phosphorylation of the N-methyl-D-aspartate receptor NR1 subunit using phosphorylation site-specific antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Protein kinase C potentiation of N-methyl-D-aspartate receptor activity is not mediated by phosphorylation of N-methyl-D-aspartate receptor subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Inhibition of protein kinase C reduces ischemia-induced tyrosine phosphorylation of the N-methyl-d-aspartate receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

NMDA receptor subunits in the postsynaptic density of rat brain: expression and phosphorylation by endogenous protein kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Protein kinase C expression and activity after global incomplete cerebral ischemia in dogs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Studies and perspectives of protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Protein kinase C-gamma and calcium/calmodulin-dependent protein kinase II-alpha are persistently translocated to cell membranes of the rat brain during and after middle cerebral artery occlusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Activation of cPLA2, PKC, and ERKs in the rat cerebral cortex during ischemia/reperfusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Protein kinase C delta mediates cerebral reperfusion injury in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Apoptotic mechanisms after cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Protein kinase C delta modulates endothelial nitric oxide synthase after cardiac arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Regulation of cell apoptosis by protein kinase c delta

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Reactive oxygen radicals in signaling and damage in the ischemic brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Reperfusion-induced translocation of deltaPKC to cardiac mitochondria prevents pyruvate dehydrogenase reactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Translocation of deltaPKC to mitochondria during cardiac reperfusion enhances superoxide anion production and induces loss in mitochondrial function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Protein kinase Cdelta activation induces apoptosis in response to cardiac ischemia and reperfusion damage: a mechanism involving BAD and the mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Protein kinase C delta cleavage initiates an aberrant signal transduction pathway after cardiac arrest and oxygen glucose deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Neutrophil protein kinase Cdelta as a mediator of stroke-reperfusion injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Isolation of transforming murine leukemia viruses from mice with a high incidence of spontaneous lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

PKB/AKT: functional insights from genetic models

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

AKT1, AKT2 and AKT3-dependent cell survival is cell line-specific and knockdown of all three isoforms selectively induces apoptosis in 20 human tumor cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Identification of a human Akt3 (protein kinase B gamma) which contains the regulatory serine phosphorylation site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Involvement of the Akt/PKB signaling pathway with disease processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

PTEN: a tumour suppressor that functions as a phospholipid phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

SHIP's C-terminus is essential for its hydrolysis of PIP3 and inhibition of mast cell degranulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

The tyrosine phosphatase SHP2 modulates MAP kinase p38 and caspase 1 and 3 to foster neuronal survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Insulin-like growth factor-1 (IGF-1) induces the activation/phosphorylation of Akt kinase and cAMP response element-binding protein (CREB) by activating different signaling pathways in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Further evidence that the inhibition of glycogen synthase kinase-3beta by IGF-1 is mediated by PDK1/PKB-induced phosphorylation of Ser-9 and not by dephosphorylation of Tyr-216

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Glycogen synthase kinase-3 beta activity is critical for neuronal death caused by inhibiting phosphatidylinositol 3-kinase or Akt but not for death caused by nerve growth factor withdrawal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Epigallocatechin gallate prevents oxidative-stress-induced death of mutant Cu/Zn-superoxide dismutase (G93A) motoneuron cells by alteration of cell survival and death signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Growth factor withdrawal from primary human erythroid progenitors induces apoptosis through a pathway involving glycogen synthase kinase-3 and Bax.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Enhanced glycogen synthase kinase-3beta activity mediates hypoxia-induced apoptosis of vascular smooth muscle cells and is prevented by glucose transport and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Lithium protects cultured neurons against beta-amyloid-induced neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Role of mTOR in physiology and pathology of the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

LTP inhibits LTD in the hippocampus via regulation of GSK3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Neuregulin signaling through a PI3K/Akt/Bad pathway in Schwann cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Role of Akt signaling in mitochondrial survival pathway triggered by hypoxic preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

In vivo PDGF beta receptor activation in the dorsocaudal brainstem of the rat prevents hypoxia-induced apoptosis via activation of Akt and BAD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Estradiol abrogates apoptosis in breast cancer cells through inactivation of BAD: Ras-dependent nongenomic pathways requiring signaling through ERK and Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Inflammation in stroke and focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Boosting regulatory T cells limits neuroinflammation in permanent cortical stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Molecular mechanisms of apoptosis in cerebral ischemia: multiple neuroprotective opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Mitochondrial and apoptotic neuronal death signaling pathways in cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Possible contribution of proteins of Bcl-2 family in neuronal death following transient global brain ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Hypoxic preconditioning attenuates neuronal cell death by preventing MEK/ERK signaling pathway activation after transient global cerebral ischemia in adult rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Ischemic preconditioning alters the epigenetic profile of the brain from ischemic intolerance to ischemic tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Hypoxic preconditioning provides neuroprotection and increases vascular endothelial growth factor A, preserves the phosphorylation of Akt-Ser-473 and diminishes the increase in caspase-3 activity in neonatal rat hypoxic-ischemic model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Major role of the PI3K/Akt pathway in ischemic tolerance induced by sublethal oxygen-glucose deprivation in cortical neurons in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

The Akt pathway is involved in rapid ischemic tolerance in focal ischemia in Rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Antiinflammatory action of glucocorticoids--new mechanisms for old drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Dexamethasone-induced neuroprotection in hypoxic-ischemic brain injury in newborn rats is partly mediated via Akt activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

Antenatal dexamethasone and decreased birth weight

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01616412.2015.1133024

10.1080/01616412.2015.1133024

21 January 2018

Identifiers

DOI

1 reference

6 September 2017

1 reference