(Q38820863)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27128373%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

title

Alzheimer's Disease Risk Genes and Lipid Regulators (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27128373%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

0 references

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27128373%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

author name string

Farida El Gaamouch

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27128373%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Ping Jing

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27128373%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Jiahong Xia

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27128373%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

publication date

1 April 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27128373%20AND%20SRC:MED&resulttype=core&format=json

Journal of Alzheimer's Disease

3 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27128373%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

volume

53

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27128373%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27128373%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

page(s)

15-29

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27128373%20AND%20SRC:MED&resulttype=core&format=json

A century of Alzheimer's disease

3 April 2020

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Kinetics of adsorption of beta-amyloid peptide Abeta(1-40) to lipid bilayers.

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Lipid rafts in health and disease

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Omega-3 fatty acid docosahexaenoic acid increases SorLA/LR11, a sorting protein with reduced expression in sporadic Alzheimer's disease (AD): relevance to AD prevention

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21 January 2018

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21 January 2018

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Diet-induced hypercholesterolemia enhances brain A beta accumulation in transgenic mice

21 January 2018

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Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease

21 January 2018

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21 January 2018

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Presenilin mutations linked to familial Alzheimer's disease cause an imbalance in phosphatidylinositol 4,5-bisphosphate metabolism

21 January 2018

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Oligomeric amyloid-beta peptide disrupts phosphatidylinositol-4,5-bisphosphate metabolism

21 January 2018

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Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease

21 January 2018

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21 January 2018

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Brain membrane phospholipid alterations in Alzheimer's disease

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21 January 2018

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Human apoE targeted replacement mouse lines: h-apoE4 and h-apoE3 mice differ on spatial memory performance and avoidance behavior

21 January 2018

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21 January 2018

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21 January 2018

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Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease

21 January 2018

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Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

21 January 2018

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Cerebrovascular disease, the apolipoprotein e4 allele, and cognitive decline in a community-based study of elderly men.

21 January 2018

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Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

21 January 2018

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Midlife cardiovascular risk factors, ApoE, and cognitive decline in elderly male twins

21 January 2018

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The role of APOE epsilon4 in modulating effects of other risk factors for cognitive decline in elderly persons

21 January 2018

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Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study

21 January 2018

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Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism

21 January 2018

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Plasticity and the spread of Alzheimer's disease-like changes

21 January 2018

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Genetic association of acyl-coenzyme A: cholesterol acyltransferase with cerebrospinal fluid cholesterol levels, brain amyloid load, and risk for Alzheimer's disease

21 January 2018

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Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides

21 January 2018

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ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions

21 January 2018

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Association of apolipoprotein E genotype with brain levels of apolipoprotein E and apolipoprotein J (clusterin) in Alzheimer disease.

21 January 2018

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Alzheimer vaccine: amyloid-beta on trial.

21 January 2018

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The levels of soluble amyloid beta in different high density lipoprotein subfractions distinguish Alzheimer's and normal aging cerebrospinal fluid: implication for brain cholesterol pathology?

21 January 2018

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A nontransgenic mouse model shows inducible amyloid-beta (Abeta) peptide deposition and elucidates the role of apolipoprotein E in the amyloid cascade

21 January 2018

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Apolipoprotein E, amyloid, and Alzheimer disease

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21 January 2018

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21 January 2018

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Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system

21 January 2018

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The role of the cell surface LRP and soluble LRP in blood-brain barrier Abeta clearance in Alzheimer's disease

21 January 2018

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Low-density lipoprotein receptor family: endocytosis and signal transduction

21 January 2018

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Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

21 January 2018

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New therapeutic targets in the neurovascular pathway in Alzheimer's disease

21 January 2018

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Apolipoprotein E in Alzheimer's disease and other neurological disorders

21 January 2018

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Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3

21 January 2018

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21 January 2018

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Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain

21 January 2018

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22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion

21 January 2018

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Genetic variants of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism

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ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.

21 January 2018

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Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice

21 January 2018

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Cellular cholesterol efflux to serum is impaired in diabetic nephropathy

21 January 2018

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ApoE promotes the proteolytic degradation of Abeta

21 January 2018

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Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice

21 January 2018

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Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

21 January 2018

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Roles of ATP-binding cassette transporter A7 in cholesterol homeostasis and host defense system

21 January 2018

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Regulation and Mechanisms of ATP-Binding Cassette Transporter A1-Mediated Cellular Cholesterol Efflux

21 January 2018

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Human ABCA7 supports apolipoprotein-mediated release of cellular cholesterol and phospholipid to generate high density lipoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

ATP-binding cassette transporter A7 regulates processing of amyloid precursor protein in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Deletion of Abca7 increases cerebral amyloid-β accumulation in the J20 mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Phospholipase D1 corrects impaired betaAPP trafficking and neurite outgrowth in familial Alzheimer's disease-linked presenilin-1 mutant neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Enhancement of phospholipase D activity by overexpression of amyloid precursor protein in P19 mouse embryonic carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Amyloid beta-induced neurotoxicity is associated with phospholipase D activation in cultured rat hippocampal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

PLD3 in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

PLD3 in non-familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Rare Variants in PLD3 Do Not Affect Risk for Early-Onset Alzheimer Disease in a European Consortium Cohort

21 January 2018

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https://api.crossref.org/works/10.3233%2FJAD-160169

A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease

21 January 2018

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The Alzheimer's disease mitochondrial cascade hypothesis

21 January 2018

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Lipidomic analysis and electron transport chain activities in C57BL/6J mouse brain mitochondria

21 January 2018

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Making heads or tails of phospholipids in mitochondria

21 January 2018

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Gluing the respiratory chain together. Cardiolipin is required for supercomplex formation in the inner mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Cardiolipin, a critical determinant of mitochondrial carrier protein assembly and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Role of cardiolipin alterations in mitochondrial dysfunction and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Cardiolipins and biomembrane function

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Mass spectrometry of intact V-type ATPases reveals bound lipids and the effects of nucleotide binding

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Interaction of peroxidized cardiolipin with rat-heart mitochondrial membranes: induction of permeability transition and cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Cytochrome c/cardiolipin relations in mitochondria: a kiss of death

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Cardiolipin: characterization of distinct oxidized molecular species

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Transient Formation of Superoxide Radicals in Polyunsaturated Fatty Acid-Induced Brain Swelling

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Impaired cerebral mitochondrial function after traumatic brain injury in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

F(2)-isoprostanes: sensitive and specific non-invasive indices of lipid peroxidation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Thromboxane, prostacyclin and isoprostanes: therapeutic targets in atherogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Release of free F2-isoprostanes from esterified phospholipids is catalyzed by intracellular and plasma platelet-activating factor acetylhydrolases

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

HDL is the major lipoprotein carrier of plasma F2-isoprostanes

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Chronic melatonin therapy fails to alter amyloid burden or oxidative damage in old Tg2576 mice: implications for clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Deletion of the prostaglandin E2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Involvement of thromboxane receptor in the proatherogenic effect of isoprostane F2alpha-III: evidence from apolipoprotein E- and LDL receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Alzheimer's disease and oxygen radicals: new insights

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Thiamine deficiency induces oxidative stress and exacerbates the plaque pathology in Alzheimer's mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Abeta production in APP23 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Thromboxane receptor activation mediates isoprostane-induced increases in amyloid pathology in Tg2576 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Brain regional quantification of F-ring and D-/E-ring isoprostanes and neuroprostanes in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Cerebrospinal fluid F2-isoprostane levels are increased in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Evidence of increased oxidative damage in subjects with mild cognitive impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Increased CSF F2-isoprostane concentration in probable AD.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Prediction and longitudinal study of CSF biomarkers in mild cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Hypometabolism and altered cerebrospinal fluid markers in normal apolipoprotein E E4 carriers with subjective memory complaints

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Longitudinal CSF isoprostane and MRI atrophy in the progression to AD.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

The effects of normal aging and ApoE genotype on the levels of CSF biomarkers for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Formation of isoprostane-like compounds (neuroprostanes) in vivo from docosahexaenoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

Cerebrospinal fluid biomarkers for neuropsychological symptoms in early stage of late-onset Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160169

21 January 2018

Identifiers

DOI

10.3233/JAD-160169

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27128373%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

1 reference