(Q38826788)

English

Phenethyl isothiocyanate, by virtue of its antioxidant activity, inhibits invasiveness and metastatic potential of breast cancer cells: HIF-1α as a putative target

scientific article published on 19 October 2015

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scholarly article

1 reference

Europe PubMed Central

6 September 2017

Phenethyl isothiocyanate, by virtue of its antioxidant activity, inhibits invasiveness and metastatic potential of breast cancer cells: HIF-1α as a putative target (English)

1 reference

Europe PubMed Central

6 September 2017

neoplastic invasiveness

1 reference

based on heuristic

inferred from title

metastatic potential

1 reference

based on heuristic

inferred from title

author name string

Ruma Sarkar

1

1 reference

Europe PubMed Central

6 September 2017

Sutapa Mukherjee

2

1 reference

Europe PubMed Central

6 September 2017

Jaydip Biswas

3

1 reference

Europe PubMed Central

6 September 2017

Madhumita Roy

4

1 reference

Europe PubMed Central

6 September 2017

publication date

19 October 2015

1 reference

Europe PubMed Central

6 September 2017

Free Radical Research

1 reference

Europe PubMed Central

6 September 2017

50

1 reference

Europe PubMed Central

6 September 2017

1

1 reference

Europe PubMed Central

6 September 2017

84-100

1 reference

Europe PubMed Central

6 September 2017

Inhibition of breast cancer metastases by a novel inhibitor of TGFβ receptor 1.

1 reference

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21 January 2018

Breast cancer metastasis driven by ErbB2 and 14-3-3zeta: A division of labor

1 reference

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21 January 2018

Time-dependent stabilization of hypoxia inducible factor-1α by different intracellular sources of reactive oxygen species

1 reference

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21 January 2018

Tumor hypoxia: causative factors, compensatory mechanisms, and cellular response

1 reference

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21 January 2018

Reactive oxygen species: role in the development of cancer and various chronic conditions

1 reference

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21 January 2018

Mitochondrial reactive oxygen species trigger hypoxia-inducible factor-dependent extension of the replicative life span during hypoxia

1 reference

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21 January 2018

Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

1 reference

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21 January 2018

Redox regulation in cancer: a double-edged sword with therapeutic potential

1 reference

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21 January 2018

Reactive oxygen species in cancer

1 reference

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21 January 2018

Hypoxia-inducible factor-1alpha is a key regulator of metastasis in a transgenic model of cancer initiation and progression.

1 reference

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21 January 2018

Reactive oxygen species and HIF-1 signalling in cancer

1 reference

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21 January 2018

Transcription factor YY1 contributes to tumor growth by stabilizing hypoxia factor HIF-1α in a p53-independent manner.

1 reference

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21 January 2018

PI3K and ERK-induced Rac1 activation mediates hypoxia-induced HIF-1α expression in MCF-7 breast cancer cells

1 reference

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21 January 2018

In vitro study of HIF-1 activation and VEGF release by bFGF in the T47D breast cancer cell line under normoxic conditions: involvement of PI-3K/Akt and MEK1/ERK pathways.

1 reference

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21 January 2018

Deferoxamine promotes MDA-MB-231 cell migration and invasion through increased ROS-dependent HIF-1α accumulation

1 reference

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21 January 2018

Interaction of the PAS B domain with HSP90 accelerates hypoxia-inducible factor-1alpha stabilization.

1 reference

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21 January 2018

New developments in Hsp90 inhibitors as anti-cancer therapeutics: mechanisms, clinical perspective and more potential.

1 reference

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21 January 2018

Degradation of HIF-1alpha under hypoxia combined with induction of Hsp90 polyubiquitination in cancer cells by hypericin: a unique cancer therapy

1 reference

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21 January 2018

Hemin, an iron-binding porphyrin, inhibits HIF-1α induction through its binding with heat shock protein 90.

1 reference

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21 January 2018

Curcumin augments the efficacy of antitumor drugs used in leukemia by modulation of heat shock proteins via HDAC6.

1 reference

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21 January 2018

Antioxidant-mediated up-regulation of OGG1 via NRF2 induction is associated with inhibition of oxidative DNA damage in estrogen-induced breast cancer

1 reference

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21 January 2018

Nutritional strategies to modulate inflammation and oxidative stress pathways via activation of the master antioxidant switch Nrf2.

1 reference

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21 January 2018

Chemoprevention of dietary digitoflavone on colitis-associated colon tumorigenesis through inducing Nrf2 signaling pathway and inhibition of inflammation

1 reference

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21 January 2018

Oncogenic transformation of mesenchymal stem cells decreases Nrf2 expression favoring in vivo tumor growth and poorer survival

1 reference

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21 January 2018

Cul3 overexpression depletes Nrf2 in breast cancer and is associated with sensitivity to carcinogens, to oxidative stress, and to chemotherapy

1 reference

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21 January 2018

Novel function of transcription factor Nrf2 as an inhibitor of RON tyrosine kinase receptor-mediated cancer cell invasion

1 reference

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21 January 2018

Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung.

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2015.1108520

21 January 2018

The transcription factor NF-E2-related factor 2 (Nrf2): a protooncogene?

1 reference

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21 January 2018

E-cadherin inhibits nuclear accumulation of Nrf2: implications for chemoresistance of cancer cells

1 reference

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21 January 2018

Apoptosis Induction by Polygonum minus is related to antioxidant capacity, alterations in expression of apoptotic-related genes, and S-phase cell cycle arrest in HepG2 cell line

1 reference

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21 January 2018

Multiple dietary antioxidants enhance the efficacy of standard and experimental cancer therapies and decrease their toxicity

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2015.1108520

21 January 2018

Dietary phenethylisothiocyanate attenuates bowel inflammation in mice

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2015.1108520

21 January 2018

Phenethylisothiocyanate alters site- and promoter-specific histone tail modifications in cancer cells

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2015.1108520

21 January 2018

Antioxidant and pro-oxidant capacities of ITCs

1 reference

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21 January 2018

Mechanism-based in vitro screening of potential cancer chemopreventive agents

1 reference

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21 January 2018

Chemoprevention of acrylamide toxicity by antioxidative agents in rats--effective suppression of testicular toxicity by phenylethyl isothiocyanate

1 reference

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21 January 2018

In vitro and in vivo anti-inflammatory activity of a seed preparation containing phenethylisothiocyanate

1 reference

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21 January 2018

Metabolic regulation and redox activity as mechanisms for angioprevention by dietary phytochemicals

1 reference

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21 January 2018

The time-dependent effect of gluconasturtiin and phenethyl isothiocyanate on metabolic and antioxidative parameters in rats

1 reference

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21 January 2018

Differential induction of apoptosis in human breast cancer cell lines by phenethyl isothiocyanate, a glutathione depleting agent.

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2015.1108520

21 January 2018

Targeting heat shock proteins by phenethyl isothiocyanate results in cell-cycle arrest and apoptosis of human breast cancer cells

1 reference

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21 January 2018

Selective uncoupling of p120(ctn) from E-cadherin disrupts strong adhesion

1 reference

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MMP-9, uPAR and cathepsin B silencing downregulate integrins in human glioma xenograft cells in vitro and in vivo in nude mice

1 reference

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Non-angiogenic functions of VEGF in breast cancer

1 reference

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21 January 2018

Unravelling the complexity of metastasis - molecular understanding and targeted therapies

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21 January 2018

Cancer and metastasis: prevention and treatment by green tea

1 reference

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Hypoxia-inducible factor 1 and breast cancer metastasis

1 reference

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21 January 2018

Role of oxidative stress and the microenvironment in breast cancer development and progression

1 reference

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Hypoxia and oxidative stress in breast cancer. Oxidative stress: its effects on the growth, metastatic potential and response to therapy of breast cancer

1 reference

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Cancer cell killing via ROS: to increase or decrease, that is the question

1 reference

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Hypoxia-inducible factor (HIF)-1 alpha directly enhances the transcriptional activity of stem cell factor (SCF) in response to hypoxia and epidermal growth factor (EGF).

1 reference

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21 January 2018

A potentially common peptide target in secreted heat shock protein-90α for hypoxia-inducible factor-1α-positive tumors

1 reference

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21 January 2018

Reactive oxygen species stabilize hypoxia-inducible factor-1 alpha protein and stimulate transcriptional activity via AMP-activated protein kinase in DU145 human prostate cancer cells

1 reference

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21 January 2018

Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway

1 reference

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21 January 2018

Hypoxia-induced activation of HIF-1: role of HIF-1alpha-Hsp90 interaction

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2015.1108520

21 January 2018

Inhibition of hypoxia inducible factor by phenethyl isothiocyanate.

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2015.1108520

21 January 2018

Hypoxia increases the metastatic ability of breast cancer cells via upregulation of CXCR4

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2015.1108520

21 January 2018

Expression of matrix metalloproteinases in human breast cancer tissues

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2015.1108520

21 January 2018

Hypoxia stimulates breast carcinoma cell invasion through MT1-MMP and MMP-2 activation

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2015.1108520

21 January 2018

Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B.

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2015.1108520

21 January 2018

Overexpression of MMP-9 and HIF-1α in Breast Cancer Cells under Hypoxic Conditions

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2015.1108520

21 January 2018

Hypoxic induction of HIF-1alpha and VEGF expression in head and neck squamous cell carcinoma lines is mediated by stress activated protein kinases

1 reference

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21 January 2018

Antioxidant Determinations by the Use of a Stable Free Radical

1 reference

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21 January 2018

Identifiers

10.3109/10715762.2015.1108520

1 reference

Europe PubMed Central

6 September 2017

1 reference

Europe PubMed Central

6 September 2017

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