(Q38830228)

English

Global analysis of physical and functional RNA targets of hnRNP L reveals distinct sequence and epigenetic features of repressed and enhanced exons

scientific article published on 5 October 2015

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scholarly article

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Europe PubMed Central

6 September 2017

Global analysis of physical and functional RNA targets of hnRNP L reveals distinct sequence and epigenetic features of repressed and enhanced exons (English)

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Europe PubMed Central

6 September 2017

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Samuel J Allon

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Brian S Cole

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Europe PubMed Central

6 September 2017

Iulia Tapescu

2

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Europe PubMed Central

6 September 2017

Michael J Mallory

4

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Europe PubMed Central

6 September 2017

Jinsong Qiu

5

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Europe PubMed Central

6 September 2017

Robert J Lake

6

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Europe PubMed Central

6 September 2017

Hua-Ying Fan

7

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Europe PubMed Central

6 September 2017

Xiang-Dong Fu

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Kristen W Lynch

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6 September 2017

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5 October 2015

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Europe PubMed Central

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

2053-2066

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6 September 2017

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22 June 2022

https://europepmc.org/article/PMC/4647460

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The end of the message: multiple protein-RNA interactions define the mRNA polyadenylation site

1 reference

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Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development

1 reference

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1 reference

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limma powers differential expression analyses for RNA-sequencing and microarray studies

1 reference

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9 September 2017

Widespread intron retention in mammals functionally tunes transcriptomes

1 reference

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A global regulatory mechanism for activating an exon network required for neurogenesis

1 reference

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The splicing factor RBM4 controls apoptosis, proliferation, and migration to suppress tumor progression

1 reference

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Context-dependent control of alternative splicing by RNA-binding proteins

1 reference

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The RNA-binding protein hnRNPLL induces a T cell alternative splicing program delineated by differential intron retention in polyadenylated RNA.

1 reference

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Independent RNA polymerase II preinitiation complex dynamics and nucleosome turnover at promoter sites in vivo

1 reference

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9 September 2017

Transcriptome-wide RNA interaction profiling reveals physical and functional targets of hnRNP L in human T cells

1 reference

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Set2 mediated H3 lysine 36 methylation: regulation of transcription elongation and implications in organismal development

1 reference

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9 September 2017

Identifying differential alternative splicing events from RNA sequencing data using RNASeq-MATS.

1 reference

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9 September 2017

A compendium of RNA-binding motifs for decoding gene regulation.

1 reference

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9 September 2017

DNA methylation determines nucleosome occupancy in the 5'-CpG islands of tumor suppressor genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Minimal functional domains of paralogues hnRNP L and hnRNP LL exhibit mechanistic differences in exonic splicing repression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Dynamic integration of splicing within gene regulatory pathways

1 reference

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9 September 2017

Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits

1 reference

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9 September 2017

Chromatin and epigenetic regulation of pre-mRNA processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Alternative splicing controlled by heterogeneous nuclear ribonucleoprotein L regulates development, proliferation, and migration of thymic pre-T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

RASL-seq for massively parallel and quantitative analysis of gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

MATS: a Bayesian framework for flexible detection of differential alternative splicing from RNA-Seq data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Degrade, move, regroup: signaling control of splicing proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Chromatin density and splicing destiny: on the cross-talk between chromatin structure and splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Regulation of alternative splicing by histone modifications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Context-dependent regulatory mechanism of the splicing factor hnRNP L.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Expansion of the eukaryotic proteome by alternative splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

G+C content dominates intrinsic nucleosome occupancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

RNA processing and its regulation: global insights into biological networks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Heterogeneous nuclear ribonucleoprotein L Is a subunit of human KMT3a/Set2 complex required for H3 Lys-36 trimethylation activity in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

RNA and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

The spliceosome: design principles of a dynamic RNP machine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

1 reference

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9 September 2017

HITS-CLIP yields genome-wide insights into brain alternative RNA processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Alternative isoform regulation in human tissue transcriptomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

A cell-based screen for splicing regulators identifies hnRNP LL as a distinct signal-induced repressor of CD45 variable exon 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Regulation of alternative splicing by signal transduction pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

hnRNP proteins and splicing control.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Diverse roles of hnRNP L in mammalian mRNA processing: a combined microarray and RNAi analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Regulation of alternative splicing: more than just the ABCs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Global analysis of alternative splicing during T-cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Exon silencing by UAGG motifs in response to neuronal excitation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Structure of human MRG15 chromo domain and its binding to Lys36-methylated histone H3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

The architecture of pre-mRNAs affects mechanisms of splice-site pairing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

HnRNP L represses exon splicing via a regulated exonic splicing silencer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Intronic CA-repeat and CA-rich elements: a new class of regulators of mammalian alternative splicing

1 reference

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9 September 2017

Cell signalling and the control of pre-mRNA splicing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

hnRNP K: one protein multiple processes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

Insulin regulates alternative splicing of protein kinase C beta II through a phosphatidylinositol 3-kinase-dependent pathway involving the nuclear serine/arginine-rich splicing factor, SRp40, in skeletal muscle cells

1 reference

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9 September 2017

An oxygen-regulated switch in the protein synthesis machinery

1 reference

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9 September 2017

Alternative splicing networks regulated by signaling in human T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

HnRNP L and L-like cooperate in multiple-exon regulation of CD45 alternative splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

A model system for activation-induced alternative splicing of CD45 pre-mRNA in T cells implicates protein kinase C and Ras.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

9 September 2017

An ESRP-regulated splicing programme is abrogated during the epithelial-mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

14 September 2017

DNA-methylation effect on cotranscriptional splicing is dependent on GC architecture of the exon-intron structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

14 September 2017

Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

25 September 2017

A CaMK IV responsive RNA element mediates depolarization-induced alternative splicing of ion channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

25 September 2017

hnRNP L and hnRNP A1 induce extended U1 snRNA interactions with an exon to repress spliceosome assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

25 September 2017

RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

17 June 2018

Relationship between nucleosome positioning and DNA methylation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

17 June 2018

Differential expression of CD45 isoforms is controlled by the combined activity of basal and inducible splicing-regulatory elements in each of the variable exons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

17 June 2018

Immunopurification of heterogeneous nuclear ribonucleoprotein particles reveals an assortment of RNA-binding proteins.

1 reference

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17 June 2018

Mediator complex regulates alternative mRNA processing via the MED23 subunit.

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22 August 2018

Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

22 August 2018

An RNA map predicting Nova-dependent splicing regulation.

1 reference

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22 August 2018

Maximum entropy modeling of short sequence motifs with applications to RNA splicing signals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

22 August 2018

Differential GC Content between Exons and Introns Establishes Distinct Strategies of Splice-Site Recognition

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647460

3 December 2018

A point mutation in PTPRC is associated with the development of multiple sclerosis

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3 December 2018

When chromatin meets splicing

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An exonic splicing silencer represses spliceosome assembly after ATP-dependent exon recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/26437669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

When epigenetics meets alternative splicing: the roles of DNA methylation and GC architecture

1 reference

https://pubmed.ncbi.nlm.nih.gov/26437669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1261/RNA.052969.115

1 reference

Europe PubMed Central

6 September 2017

release_cezllqb7xnf27bud6thbkdbfk4

1 reference

https://api.fatcat.wiki/v0/release/cezllqb7xnf27bud6thbkdbfk4

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

6 September 2017

1 reference

Europe PubMed Central

6 September 2017

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