(Q38844375)

1 July 2019

review article

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title

Role of the Kynurenine Metabolism Pathway in Inflammation-Induced Depression: Preclinical Approaches (English)

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1 July 2019

Robert Dantzer

1

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publication date

1 January 2017

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1 July 2019

Current topics in behavioral neurosciences

published in

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1 July 2019

volume

31

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1 July 2019

page(s)

117-138

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1 July 2019

Prevention of allogeneic fetal rejection by tryptophan catabolism

cites work

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Cytokine-induced sickness behavior: where do we stand?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Association between decreased serum tryptophan concentrations and depressive symptoms in cancer patients undergoing cytokine therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

The enzyme indoleamine 2,3-dioxygenase is induced in the mouse brain in response to peripheral administration of lipopolysaccharide and superantigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Lipopolysaccharide induces delayed FosB/DeltaFosB immunostaining within the mouse extended amygdala, hippocampus and hypothalamus, that parallel the expression of depressive-like behavior.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Neurobehavioral effects of interferon-alpha in cancer patients: phenomenology and paroxetine responsiveness of symptom dimensions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Immune system to brain signaling: neuropsychopharmacological implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Bacille Calmette-Guérin inoculation induces chronic activation of peripheral and brain indoleamine 2,3-dioxygenase in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Inoculation of Bacillus Calmette-Guerin to mice induces an acute episode of sickness behavior followed by chronic depressive-like behavior.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Interferon-gamma and tumor necrosis factor-alpha mediate the upregulation of indoleamine 2,3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus Calmette-Guerin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Induction of IDO by bacille Calmette-Guérin is responsible for development of murine depressive-like behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Biochemical and medical aspects of the indoleamine 2,3-dioxygenase-initiated L-tryptophan metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Induction of pulmonary indoleamine 2,3-dioxygenase by intraperitoneal injection of bacterial lipopolysaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Induction of indoleamine 2,3-dioxygenase in mouse lung during virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Indoleamine 2,3 dioxygenase and metabolic control of immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Aryl hydrocarbon receptor: Linking environment to immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Aryl hydrocarbon receptor control of a disease tolerance defence pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Aryl hydrocarbon receptor in combination with Stat1 regulates LPS-induced inflammatory responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Inhibition of allogeneic T cell proliferation by indoleamine 2,3-dioxygenase-expressing dendritic cells: mediation of suppression by tryptophan metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Amino acid control of neurotransmitter synthesis and release: physiological and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Kynurenines in the mammalian brain: when physiology meets pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Brain serotonin content: physiological dependence on plasma tryptophan levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Dietary Precursors and Brain Neurotransmitter Formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Tryptophan Pyrrolase—A Biochemical Factor in Depressive Illness?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Tryptophan metabolism in depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

The acute effects of oral (-)-tryptophan in human subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

The effect of raising and lowering tryptophan levels on human mood and social behaviour

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Mood is indirectly related to serotonin, norepinephrine and dopamine levels in humans: a meta-analysis of monoamine depletion studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Expression of indoleamine 2,3-dioxygenase and production of quinolinic acid by human microglia, astrocytes, and neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

From inflammation to sickness and depression: when the immune system subjugates the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

NMDA receptor blockade by ketamine abrogates lipopolysaccharide-induced depressive-like behavior in C57BL/6J mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Is there a role for glutamate-mediated excitotoxicity in inflammation-induced depression?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Blood?Brain Barrier Transport of Kynurenines: Implications for Brain Synthesis and Metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Effects of systemic and central nervous system localized inflammation on the contributions of metabolic precursors to the L-kynurenine and quinolinic acid pools in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Amino acids inhibit kynurenic acid formation via suppression of kynurenine uptake or kynurenic acid synthesis in rat brain in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

System xc⁻ cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

System x(c)(-) regulates microglia and macrophage glutamate excitotoxicity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Neuroinflammation and regulation of glial glutamate uptake in neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Intracerebroventricular administration of HIV-1 Tat induces brain cytokine and indoleamine 2,3-dioxygenase expression: a possible mechanism for AIDS comorbid depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

HIV-1 Tat activates indoleamine 2,3 dioxygenase in murine organotypic hippocampal slice cultures in a p38 mitogen-activated protein kinase-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Poly I:C-induced activation of the immune response is accompanied by depression and anxiety-like behaviours, kynurenine pathway activation and reduced BDNF expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

The kynurenine pathway contributes to long-term neuropsychological changes in experimental pneumococcal meningitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Behavioral Deficits Are Accompanied by Immunological and Neurochemical Changes in a Mouse Model for Neuropsychiatric Lupus (NP-SLE).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

CD40-TNF activation in mice induces extended sickness behavior syndrome co-incident with but not dependent on activation of the kynurenine pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Inflamm-aging. An evolutionary perspective on immunosenescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Aging exacerbates depressive-like behavior in mice in response to activation of the peripheral innate immune system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1beta and anti-inflammatory IL-10 cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Aging leads to prolonged duration of inflammation-induced depression-like behavior caused by Bacillus Calmette-Guérin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Peripheral indoleamine 2,3-dioxygenase 1 is required for comorbid depression-like behavior but does not contribute to neuropathic pain in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Peripheral and cerebral metabolic abnormalities of the tryptophan-kynurenine pathway in a murine model of major depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Maternal separation induces neuroinflammation and long-lasting emotional alterations in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Long-lasting effects of inescapable-predator stress on brain tryptophan metabolism and the behavior of juvenile mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Inhibition of stress-induced hepatic tryptophan 2,3-dioxygenase exhibits antidepressant activity in an animal model of depressive behaviour.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

The etiology of poststroke depression: a review of the literature and a new hypothesis involving inflammatory cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Activation of brain indoleamine 2,3-dioxygenase contributes to epilepsy-associated depressive-like behavior in rats with chronic temporal lobe epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Effects of the total flavonoid extract of Xiaobuxin-Tang on depression-like behavior induced by lipopolysaccharide and proinflammatory cytokine levels in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Effects of perillaldehyde on alternations in serum cytokines and depressive-like behavior in mice after lipopolysaccharide administration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Peripheral anti-inflammatory effects explain the ginsenosides paradox between poor brain distribution and anti-depression efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

The effects of apigenin on lipopolysaccharide-induced depressive-like behavior in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Antidepressant-like effect of α-tocopherol in a mouse model of depressive-like behavior induced by TNF-α.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Honokiol abrogates lipopolysaccharide-induced depressive like behavior by impeding neuroinflammation and oxido-nitrosative stress in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

The effects of curcumin on depressive-like behavior in mice after lipopolysaccharide administration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

A critical review of the mechanism of action for the selective serotonin reuptake inhibitors: do these drugs possess anti-inflammatory properties and how relevant is this in the treatment of depression?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Trypanosoma cruzi-induced depressive-like behavior is independent of meningoencephalitis but responsive to parasiticide and TNF-targeted therapeutic interventions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Depressive-like behavior induced by tumor necrosis factor-α in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Fluoxetine prevents the development of depressive-like behavior in a mouse model of cancer related fatigue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Ibuprofen ameliorates fatigue- and depressive-like behavior in tumor-bearing mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Bacillus Calmette-Guérin vaccine induces a selective serotonin reuptake inhibitor (SSRI)-resistant depression like phenotype in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Peripheral and central mechanisms involved in the control of food intake by dietary amino acids and proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Indoleamine 2,3-dioxygenase-dependent neurotoxic kynurenine metabolism mediates inflammation-induced deficit in recognition memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Metabolism and pharmacokinetics of JM6 in mice: JM6 is not a prodrug for Ro-61-8048.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Effects of ketamine on endotoxin and traumatic brain injury induced cytokine production in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Ketamine-mediated alleviation of electroconvulsive shock-induced memory impairment is associated with the regulation of neuroinflammation and soluble amyloid-beta peptide in depressive-like rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_6

Therapeutic use of branched-chain amino acids in burn, trauma, and sepsis

21 January 2018

1 reference

12 December 2020

NF-kappa B activation contributes to indoleamine dioxygenase transcriptional synergy induced by IFN-gamma and tumor necrosis factor-alpha

1 reference

12 December 2020

Relationship between interferon-gamma, indoleamine 2,3-dioxygenase, and tryptophan catabolism

1 reference

12 December 2020

The impact of neuroimmune dysregulation on neuroprotection and neurotoxicity in psychiatric disorders--relation to drug treatment.

1 reference

12 December 2020

Vascular expression, activity and function of indoleamine 2,3-dioxygenase-1 following cerebral ischaemia-reperfusion in mice

1 reference

12 December 2020

High-affinity uptake of L-kynurenine by a Na+-independent transporter of neutral amino acids in astrocytes

1 reference

12 December 2020

Interaction of kynurenine and its metabolites with tryptamine, serotonin and its precursors and oxotremorine

1 reference

12 December 2020

Stimulant and convulsive effects of kynurenines injected into brain ventricles in mice

1 reference

12 December 2020

Antagonism of kynurenine-induced seizures by picolinic, kynurenic and xanthurenic acids

1 reference

12 December 2020

Nitric oxide inhibits indoleamine 2,3-dioxygenase activity in interferon-gamma primed mononuclear phagocytes.

1 reference

12 December 2020

Species heterogeneity between gerbils and rats: quinolinate production by microglia and astrocytes and accumulations in response to ischemic brain injury and systemic immune activation.

1 reference

12 December 2020

Identifiers

DOI

10.1007/7854_2016_6

1 reference

1 July 2019

PMCID

6585430

1 reference

1 July 2019

PubMed ID

27225497

1 reference

1 July 2019