(Q38856195)

27 February 2018

review article

1 reference

title

Structure and mechanism of assembly line polyketide synthases (English)

1 reference

27 February 2018

author

Yu-Chen Liu

2

1 reference

27 February 2018

Chaitan Khosla

4

object named as

Chaitan Khosla

1 reference

27 February 2018

author name string

Thomas Robbins

1

1 reference

27 February 2018

David E Cane

3

1 reference

27 February 2018

language of work or name

1 reference

4 June 2016

1 reference

27 February 2018

Current Opinion in Structural Biology

published in

1 reference

27 February 2018

volume

41

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27 February 2018

page(s)

10-18

1 reference

27 February 2018

Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases

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17 June 2018

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17 June 2018

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17 June 2018

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Structural rearrangements of a polyketide synthase module during its catalytic cycle

17 June 2018

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Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases

17 June 2018

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17 June 2018

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Architectures of whole-module and bimodular proteins from the 6-deoxyerythronolide B synthase

17 June 2018

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Computational identification and analysis of orphan assembly-line polyketide synthases

17 June 2018

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In vitro reconstitution and analysis of the 6-deoxyerythronolide B synthase

17 June 2018

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The Missing Linker: A Dimerization Motif Located within Polyketide Synthase Modules

17 June 2018

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The structures of type I polyketide synthases

17 June 2018

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Divergence of multimodular polyketide synthases revealed by a didomain structure

17 June 2018

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Reprogramming a module of the 6-deoxyerythronolide B synthase for iterative chain elongation

17 June 2018

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Structure and Mechanism of the trans -Acting Acyltransferase from the Disorazole Synthase

17 June 2018

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Structural and functional analysis of C2-type ketoreductases from modular polyketide synthases

17 June 2018

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Molecular recognition between ketosynthase and acyl carrier protein domains of the 6-deoxyerythronolide B synthase

17 June 2018

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Structural and functional analysis of A-type ketoreductases from the amphotericin modular polyketide synthase

17 June 2018

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Biochemical and Structural Characterization of the Tautomycetin Thioesterase: Analysis of a Stereoselective Polyketide Hydrolase

17 June 2018

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

17 June 2018

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Isoprenoid-like alkylations in polyketide biosynthesis

17 June 2018

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The crystal structure of a mammalian fatty acid synthase

17 June 2018

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Solution structure and proposed domain-domain recognition interface of an acyl carrier protein domain from a modular polyketide synthase

17 June 2018

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Structural and Mechanistic Analysis of Protein Interactions in Module 3 of the 6-Deoxyerythronolide B Synthase

17 June 2018

1 reference

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A tylosin ketoreductase reveals how chirality is determined in polyketides

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5136517

Structure and mechanism of the 6-deoxyerythronolide B synthase

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5136517

The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5136517

Extender unit and acyl carrier protein specificity of ketosynthase domains of the 6-deoxyerythronolide B synthase

17 June 2018

1 reference

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17 June 2018

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ClusPro: a fully automated algorithm for protein-protein docking

17 June 2018

1 reference

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Polyketide and nonribosomal peptide antibiotics: modularity and versatility

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5136517

The structure of docking domains in modular polyketide synthases

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5136517

Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5136517

Quantitative analysis of the relative contributions of donor acyl carrier proteins, acceptor ketosynthases, and linker regions to intermodular transfer of intermediates in hybrid polyketide synthases

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5136517

Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: Versatility from a unique substrate channel

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5136517

The Utilization of Binding Energy in Coupled Vectorial Processes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5136517

Identification of DEBS 1, DEBS 2 and DEBS 3, the multienzyme polypeptides of the erythromycin-producing polyketide synthase from Saccharopolyspora erythraea

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5136517

Structure of a modular polyketide synthase

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5136517

Rational design and assembly of synthetic trimodular polyketide synthases.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5136517

The structure of a ketoreductase determines the organization of the beta-carbon processing enzymes of modular polyketide synthases.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5136517

Understanding substrate specificity of polyketide synthase modules by generating hybrid multimodular synthases.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5136517

Selective protein-protein interactions direct channeling of intermediates between polyketide synthase modules

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5136517

Functional orientation of the acyltransferase domain in a module of the erythromycin polyketide synthase

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5136517

Evidence for two catalytically independent clusters of active sites in a functional modular polyketide synthase

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5136517

Dissecting and exploiting intermodular communication in polyketide synthases

22 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27266330

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.SBI.2016.05.009

1 reference

27 February 2018

PMCID

5136517

1 reference

27 February 2018

PubMed ID

27266330

1 reference

27 February 2018