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The APOBEC Protein Family: United by Structure, Divergent in Function
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
4930407
retrieved
7 September 2017
review article
1 reference
stated in
Europe PubMed Central
title
The APOBEC Protein Family: United by Structure, Divergent in Function
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4930407
retrieved
7 September 2017
main subject
protein structure
0 references
protein family
1 reference
based on heuristic
inferred from title
author
Harold Smith
series ordinal
3
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stated in
Europe PubMed Central
PMCID
4930407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27283515%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 June 2020
author name string
Jason D Salter
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4930407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27283515%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 June 2020
Ryan P Bennett
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
4930407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27283515%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 June 2020
publication date
30 May 2016
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Europe PubMed Central
PMCID
4930407
retrieved
7 September 2017
number of pages
17
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inferred from page(s)
published in
Trends in Biochemical Sciences
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Europe PubMed Central
PMCID
4930407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27283515%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 June 2020
volume
41
1 reference
stated in
Europe PubMed Central
PMCID
4930407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27283515%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 June 2020
page(s)
578-594
1 reference
stated in
Europe PubMed Central
PMCID
4930407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27283515%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 June 2020
issue
7
1 reference
stated in
Europe PubMed Central
PMCID
4930407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27283515%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 June 2020
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Transcriptional regulation of APOBEC3 antiviral immunity through the CBF-β/RUNX axis
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Structural Insights into HIV-1 Vif-APOBEC3F Interaction
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APOBEC3G Interacts with ssDNA by Two Modes: AFM Studies
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Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain
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The Role of the Antiviral APOBEC3 Gene Family in Protecting Chimpanzees against Lentiviruses from Monkeys
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An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers
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Structure of the Vif-binding domain of the antiviral enzyme APOBEC3G
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9 September 2017
The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization
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9 September 2017
APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophages
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PubMed Central
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9 September 2017
Consecutive interactions with HSP90 and eEF1A underlie a functional maturation and storage pathway of AID in the cytoplasm.
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PubMed Central
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9 September 2017
APOBEC3 genes: retroviral restriction factors to cancer drivers
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9 September 2017
Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA.
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9 September 2017
Human papillomavirus E6 triggers upregulation of the antiviral and cancer genomic DNA deaminase APOBEC3B
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9 September 2017
Natural polymorphisms in human APOBEC3H and HIV-1 Vif combine in primary T lymphocytes to affect viral G-to-A mutation levels and infectivity
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PubMed Central
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9 September 2017
A prevalent cancer susceptibility APOBEC3A hybrid allele bearing APOBEC3B 3'UTR enhances chromosomal DNA damage
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PubMed Central
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9 September 2017
Structural insights for HIV-1 therapeutic strategies targeting Vif.
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PubMed Central
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9 September 2017
The RNA editing enzyme APOBEC1 induces somatic mutations and a compatible mutational signature is present in esophageal adenocarcinomas.
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PubMed Central
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9 September 2017
C to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47
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PubMed Central
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9 September 2017
A DNA sequence recognition loop on APOBEC3A controls substrate specificity
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PubMed Central
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9 September 2017
The multifaceted roles of RNA binding in APOBEC cytidine deaminase functions
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PubMed Central
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9 September 2017
Structure-guided analysis of the human APOBEC3-HIV restrictome
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PubMed Central
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9 September 2017
APOBEC3 multimerization correlates with HIV-1 packaging and restriction activity in living cells.
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9 September 2017
Multiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them all
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9 September 2017
Structural determinants of HIV-1 Vif susceptibility and DNA binding in APOBEC3F
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9 September 2017
Atomic force microscopy studies of APOBEC3G oligomerization and dynamics
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PubMed Central
reference URL
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9 September 2017
The local dinucleotide preference of APOBEC3G can be altered from 5'-CC to 5'-TC by a single amino acid substitution.
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PubMed Central
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9 September 2017
Footprint of APOBEC3 on the genome of human retroelements
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PubMed Central
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9 September 2017
NMR structure of human restriction factor APOBEC3A reveals substrate binding and enzyme specificity
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PubMed Central
reference URL
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9 September 2017
Crystal Structure of the DNA Cytosine Deaminase APOBEC3F: The Catalytically Active and HIV-1 Vif-Binding Domain
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PubMed Central
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9 September 2017
Endogenous APOBEC3A DNA cytosine deaminase is cytoplasmic and nongenotoxic.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
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9 September 2017
APOBEC3B is an enzymatic source of mutation in breast cancer.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
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9 September 2017
APOBEC3G restricts HIV-1 to a greater extent than APOBEC3F and APOBEC3DE in human primary CD4+ T cells and macrophages
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
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9 September 2017
The APOBEC3C crystal structure and the interface for HIV-1 Vif binding
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
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9 September 2017
Reduced APOBEC3H variant anti-viral activities are associated with altered RNA binding activities
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
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9 September 2017
An ancient history of gene duplications, fusions and losses in the evolution of APOBEC3 mutators in mammals
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PubMed Central
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9 September 2017
APOBEC3B and AID have similar nuclear import mechanisms
1 reference
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PubMed Central
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9 September 2017
APOBEC2 is a monomer in solution: implications for APOBEC3G models
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
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9 September 2017
Functions and regulation of the APOBEC family of proteins
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
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9 September 2017
Direct evidence that RNA inhibits APOBEC3G ssDNA cytidine deaminase activity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
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9 September 2017
Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Deaminase activity on single-stranded DNA (ssDNA) occurs in vitro when APOBEC3G cytidine deaminase forms homotetramers and higher-order complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
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9 September 2017
Transcriptome-wide sequencing reveals numerous APOBEC1 mRNA-editing targets in transcript 3' UTRs
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
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9 September 2017
APOBEC3G: a double agent in defense
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Structure-function analyses point to a polynucleotide-accommodating groove essential for APOBEC3A restriction activities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Atomic force microscopy studies provide direct evidence for dimerization of the HIV restriction factor APOBEC3G
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Innate immune signaling induces high levels of TC-specific deaminase activity in primary monocyte-derived cells through expression of APOBEC3A isoforms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
APOBEC-1 complementation factor (ACF) forms RNA-dependent multimers.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Structural model for deoxycytidine deamination mechanisms of the HIV-1 inactivation enzyme APOBEC3G
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Crystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfaces
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Deficiency in APOBEC2 leads to a shift in muscle fiber type, diminished body mass, and myopathy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
A hydrodynamic analysis of APOBEC3G reveals a monomer-dimer-tetramer self-association that has implications for anti-HIV function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Defining APOBEC3 expression patterns in human tissues and hematopoietic cell subsets
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Intracellular interactions between APOBEC3G, RNA, and HIV-1 Gag: APOBEC3G multimerization is dependent on its association with RNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
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9 September 2017
RNA-dependent oligomerization of APOBEC3G is required for restriction of HIV-1
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
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9 September 2017
Carboxy-terminal domain of AID required for its mRNA complex formation in vivo
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
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9 September 2017
Structure, interaction and real-time monitoring of the enzymatic reaction of wild-type APOBEC3G
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Regulation of APOBEC3 proteins by a novel YXXL motif in human immunodeficiency virus type 1 Vif and simian immunodeficiency virus SIVagm Vif
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
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9 September 2017
Stochastic properties of processive cytidine DNA deaminases AID and APOBEC3G.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Guidelines for naming nonprimate APOBEC3 genes and proteins
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Antiretroelement activity of APOBEC3H was lost twice in recent human evolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Alternative splicing regulates activation-induced cytidine deaminase (AID): implications for suppression of AID mutagenic activity in normal and malignant B cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
The AID/APOBEC family of nucleic acid mutators.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Distinct viral determinants for the packaging of human cytidine deaminases APOBEC3G and APOBEC3C
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Interaction with 7SL RNA but not with HIV-1 genomic RNA or P bodies is required for APOBEC3F virion packaging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Evolution and diversification of lamprey antigen receptors: evidence for involvement of an AID-APOBEC family cytosine deaminase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
All APOBEC3 family proteins differentially inhibit LINE-1 retrotransposition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Myeloid differentiation and susceptibility to HIV-1 are linked to APOBEC3 expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Identification of amino acid residues in APOBEC3G required for regulation by human immunodeficiency virus type 1 Vif and Virion encapsidation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
The APOBEC-2 crystal structure and functional implications for the deaminase AID
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Antiviral protein APOBEC3G localizes to ribonucleoprotein complexes found in P bodies and stress granules
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Selective inhibition of Alu retrotransposition by APOBEC3G.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
APOBEC3 proteins inhibit human LINE-1 retrotransposition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Biochemical activities of highly purified, catalytically active human APOBEC3G: correlation with antiviral effect.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Patterns of evolution of host proteins involved in retroviral pathogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
APOBEC3A and APOBEC3B are potent inhibitors of LTR-retrotransposon function in human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
APOBEC4, a new member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases predicted by computational analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Targeted deletion of the murine apobec-1 complementation factor (acf) gene results in embryonic lethality
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
APOBEC3B and APOBEC3C are potent inhibitors of simian immunodeficiency virus replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Replication protein A interacts with AID to promote deamination of somatic hypermutation targets
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
AID: how does it aid antibody diversity?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
The generation of antibody diversity through somatic hypermutation and class switch recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
DNA deamination mediates innate immunity to retroviral infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
AID mediates hypermutation by deaminating single stranded DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Somatic hypermutation of immunoglobulin genes: merging mechanisms for genetic diversity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
The editosome for cytidine to uridine mRNA editing has a native complexity of 27S: identification of intracellular domains containing active and inactive editing factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
C-->U editing of neurofibromatosis 1 mRNA occurs in tumors that express both the type II transcript and apobec-1, the catalytic subunit of the apolipoprotein B mRNA-editing enzyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
An AU-rich sequence element (UUUN[A/U]U) downstream of the edited C in apolipoprotein B mRNA is a high-affinity binding site for Apobec-1: binding of Apobec-1 to this motif in the 3' untranslated region of c-myc increases mRNA stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Escherichia coli cytidine deaminase provides a molecular model for ApoB RNA editing and a mechanism for RNA substrate recognition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Multiple protein domains determine the cell type-specific nuclear distribution of the catalytic subunit required for apolipoprotein B mRNA editing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
A potential role for NF1 mRNA editing in the pathogenesis of NF1 tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Tissue-specific inhibition of apolipoprotein B mRNA editing in the liver by adenovirus-mediated transfer of a dominant negative mutant APOBEC-1 leads to increased low density lipoprotein in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Cloning of an Apobec-1-binding protein that also interacts with apolipoprotein B mRNA and evidence for its involvement in RNA editing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
The neurofibromatosis type I messenger RNA undergoes base-modification RNA editing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Molecular cloning of an apolipoprotein B messenger RNA editing protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Cytidine deaminase. The 2.3 A crystal structure of an enzyme: transition-state analog complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Dimeric structure of a human apolipoprotein B mRNA editing protein and cloning and chromosomal localization of its gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
9 September 2017
Zinc enhancement of cytidine deaminase activity highlights a potential allosteric role of loop-3 in regulating APOBEC3 enzymes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
14 September 2017
RNA binding to APOBEC3G induces the disassembly of functional deaminase complexes by displacing single-stranded DNA substrates.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
14 September 2017
Nuclear Exclusion of the HIV-1 host defense factor APOBEC3G requires a novel cytoplasmic retention signal and is not dependent on RNA binding.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
14 September 2017
Distinct patterns of cytokine regulation of APOBEC3G expression and activity in primary lymphocytes, macrophages, and dendritic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
14 September 2017
Nanostructures of APOBEC3G support a hierarchical assembly model of high molecular mass ribonucleoprotein particles from dimeric subunits.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
14 September 2017
Interferon-inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
14 September 2017
APOBEC3G cytidine deaminase inhibits retrotransposition of endogenous retroviruses.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
14 September 2017
Transcriptional regulation of APOBEC3G, a cytidine deaminase that hypermutates human immunodeficiency virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
14 September 2017
APOBEC3H polymorphisms and susceptibility to HIV-1 infection in an Indian population
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
25 September 2017
APOBEC3H polymorphisms associated with the susceptibility to HIV-1 infection and AIDS progression in Japanese.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
17 June 2018
Regulatable liver expression of the rabbit apolipoprotein B mRNA-editing enzyme catalytic polypeptide 1 (APOBEC-1) in mice lacking endogenous APOBEC-1 leads to aberrant hyperediting
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
17 June 2018
Apolipoprotein B mRNA editing in 12 different mammalian species: hepatic expression is reflected in low concentrations of apoB-containing plasma lipoproteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
17 June 2018
Excessive activity of apolipoprotein B mRNA editing enzyme catalytic polypeptide 2 (APOBEC2) contributes to liver and lung tumorigenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
22 August 2018
Is AID a monomer in solution?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
22 August 2018
Complementary function of the two catalytic domains of APOBEC3G.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
22 August 2018
Evolution of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
22 August 2018
Human apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G (APOBEC3G) is incorporated into HIV-1 virions through interactions with viral and nonviral RNAs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
22 August 2018
Proposed nomenclature for the catalytic subunit of the mammalian apolipoprotein B mRNA editing enzyme: APOBEC-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
22 August 2018
Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific in-frame stop codon.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4930407
retrieved
22 August 2018
APOBEC3 proteins: major players in intracellular defence against LINE-1-mediated retrotransposition
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27283515
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
STAT1-independent cell type-specific regulation of antiviral APOBEC3G by IFN-alpha
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27283515
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
apobec-1, the catalytic subunit of the mammalian apolipoprotein B mRNA editing enzyme, is a novel RNA-binding protein
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27283515
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.TIBS.2016.05.001
1 reference
stated in
Europe PubMed Central
PMCID
4930407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27283515%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 June 2020
PMCID
4930407
1 reference
stated in
Europe PubMed Central
PMCID
4930407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27283515%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 June 2020
PubMed ID
27283515
1 reference
stated in
Europe PubMed Central
PMCID
4930407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27283515%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 June 2020
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