(Q38939954)

7 September 2017

1 reference

title

The role of Pin1 in the development and treatment of cancer (English)

1 reference

7 September 2017

Sang-Hyun Min

1

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7 September 2017

Xiao Zhen Zhou

series ordinal

2

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7 September 2017

Kun Ping Lu

series ordinal

3

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7 September 2017

language of work or name

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29 August 2016

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Archives of Pharmacal Research

7 September 2017

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7 September 2017

39

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7 September 2017

12

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7 September 2017

1609-1620

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https://scigraph.springernature.com/pub.10.1007/s12272-016-0821-x

7 September 2017

0 references

cites work

Site-specific, intramolecular cross-linking of Pin1 active site residues by the lipid electrophile 4-oxo-2-nonenal

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

The prolyl isomerase Pin1 regulates the NF-kappaB signaling pathway and interleukin-8 expression in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Pin1 promotes neuronal death in stroke by stabilizing Notch intracellular domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Prevalent overexpression of prolyl isomerase Pin1 in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Fbw7α and Fbw7γ collaborate to shuttle cyclin E1 into the nucleolus for multiubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Oncogenic kinase signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

The peptidyl-isomerase Pin1 regulates p27kip1 expression through inhibition of Forkhead box O tumor suppressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

The peptidyl-prolyl isomerase Pin1 regulates phospho-Ser77 retinoic acid receptor alpha stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

SENP1 deSUMOylates and regulates Pin1 protein activity and cellular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

TPA-induced cell transformation provokes a complex formation between Pin1 and 90 kDa ribosomal protein S6 kinase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

PIN1 inhibition suppresses osteoclast differentiation and inflammatory responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Pin1-HBx interaction: a step toward understanding the significance of hepatitis B virus genotypes in hepatocarcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Acute promyelocytic leukaemia: novel insights into the mechanisms of cure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

The cell biology of disease: Acute promyelocytic leukemia, arsenic, and PML bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Regulation of Raf-1 by direct feedback phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

The peptidyl prolyl cis/trans isomerase Pin1 downregulates the Inhibitor of Apoptosis Protein Survivin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Polo-like kinase 1-mediated phosphorylation stabilizes Pin1 by inhibiting its ubiquitination in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Mitotic regulation of SEPT9 protein by cyclin-dependent kinase 1 (Cdk1) and Pin1 protein is important for the completion of cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Peptidyl-prolyl isomerase Pin1 markedly enhances the oncogenic activity of the rel proteins in the nuclear factor-kappaB family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Regulation of peptide bond cis/trans isomerization by enzyme catalysis and its implication in physiological processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Inhibition of the peptidyl-prolyl-isomerase Pin1 enhances the responses of acute myeloid leukemia cells to retinoic acid via stabilization of RARalpha and PML-RARalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

A Pin1/mutant p53 axis promotes aggressiveness in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Peptidyl Prolyl Isomerase PIN1 Directly Binds to and Stabilizes Hypoxia-Inducible Factor-1α.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Selective inactivation of parvulin-like peptidyl-prolyl cis/trans isomerases by juglone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

ATR Plays a Direct Antiapoptotic Role at Mitochondria, which Is Regulated by Prolyl Isomerase Pin1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Destabilization of KLF10, a tumor suppressor, relies on thr93 phosphorylation and isomerase association

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

PML targeting eradicates quiescent leukaemia-initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

The prolyl isomerase Pin1 regulates hypoxia-inducible transcription factor (HIF) activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Novel role of Pin1 induction in type II collagen-mediated rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

p53 negatively regulates Pin1 expression under ER stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Role of autotransplantation in the treatment of acute promyelocytic leukemia patients in remission: Fukuoka BMT Group observations and a literature review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Positive and negative regulation of granulopoiesis by endogenous RARalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Regulation of phosphatidylinositol-5-phosphate signaling by Pin1 determines sensitivity to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Proyl isomerase Pin1 facilitates ubiquitin-mediated degradation of cyclin-dependent kinase 10 to induce tamoxifen resistance in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Prolyl isomerase Pin1 negatively regulates the stability of SUV39H1 to promote tumorigenesis in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Androgen receptor serine 81 mediates Pin1 interaction and activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

The prolyl isomerase Pin1 interacts with a ribosomal protein S6 kinase to enhance insulin-induced AP-1 activity and cellular transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Essential role of Pin1 in the regulation of TRF1 stability and telomere maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Peptidyl-prolyl cis-trans isomerase Pin1 in ageing, cancer and Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Peptidyl-prolyl cis/trans isomerase Pin1 is critical for the regulation of PKB/Akt stability and activation phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Protein Never in Mitosis Gene A Interacting-1 regulates calpain activity and the degradation of cyclooxygenase-2 in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Membrane permeable cyclic peptidyl inhibitors against human Peptidylprolyl Isomerase Pin1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Pin1, a new player in the fate of HIF-1α degradation: an hypothetical mechanism inside vascular damage as Alzheimer's disease risk factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Prolyl isomerase Pin1 as a molecular target for cancer diagnostics and therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Prolyl isomerase Pin1 in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

A human peptidyl-prolyl isomerase essential for regulation of mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Function of WW domains as phosphoserine- or phosphothreonine-binding modules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Pinning down proline-directed phosphorylation signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Critical role of WW domain phosphorylation in regulating phosphoserine binding activity and Pin1 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Pin1 facilitates the phosphorylation-dependent ubiquitination of SF-1 to regulate gonadotropin beta-subunit gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

The Rab2A GTPase promotes breast cancer stem cells and tumorigenesis via Erk signaling activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Essential role of Pin1 via STAT3 signalling and mitochondria-dependent pathways in restenosis in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Effects of the chitin synthetase inhibitor plumbagin and its 2-demethyl derivative juglone on insect ecdysone 20-monooxygenase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Regulation of the transcriptional activity of c-Fos by ERK. A novel role for the prolyl isomerase PIN1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Pin1 inhibitors: Pitfalls, progress and cellular pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Phosphorylation stabilizes Nanog by promoting its interaction with Pin1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Prolyl isomerase Pin1 negatively regulates AMP-activated protein kinase (AMPK) by associating with the CBS domain in the γ subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Impaired degradation of inhibitory subunit of NF-kappa B (I kappa B) and beta-catenin as a result of targeted disruption of the beta-TrCP1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Prolyl isomerase Pin1 downregulates tumor suppressor RUNX3 in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

A distinct role for Pin1 in the induction and maintenance of pluripotency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Induction of cells with cancer stem cell properties from nontumorigenic human mammary epithelial cells by defined reprogramming factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Pin1 interacts with c-Myb in a phosphorylation-dependent manner and regulates its transactivation activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Peptidylproline cis-trans-isomerase Pin1 interacts with human T-cell leukemia virus type 1 tax and modulates its activation of NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

G protein-coupled receptor kinase 2 (GRK2) modulation and cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Mixed-lineage kinase 3 phosphorylates prolyl-isomerase Pin1 to regulate its nuclear translocation and cellular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Degradation of the tumor suppressor PML by Pin1 contributes to the cancer phenotype of breast cancer MDA-MB-231 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

PIN1 is an E2F target gene essential for Neu/Ras-induced transformation of mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

A suppressive role of the prolyl isomerase Pin1 in cellular apoptosis mediated by the death-associated protein Daxx

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Pinning down HER2-ER crosstalk in SMRT regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Pin1 is overexpressed and correlates with poor prognosis in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Prolyl isomerase PIN1 regulates DNA double-strand break repair by counteracting DNA end resection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Pin1 regulates centrosome duplication, and its overexpression induces centrosome amplification, chromosome instability, and oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Prolyl isomerase, Pin1: new findings of post-translational modifications and physiological substrates in cancer, asthma and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Dipentamethylene thiuram monosulfide is a novel inhibitor of Pin1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Pin1 inhibits PP2A-mediated Rb dephosphorylation in regulation of cell cycle and S-phase DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Essential role for the prolyl isomerase Pin1 in Toll-like receptor signaling and type I interferon-mediated immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Pin1 and Par14 peptidyl prolyl isomerase inhibitors block cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Pin1 promotes degradation of Smad proteins and their interaction with phosphorylated tau in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Epigallocatechin-gallate Suppresses Tumorigenesis by Directly Targeting Pin1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Dual function of Pin1 in NR4A nuclear receptor activation: enhanced activity of NR4As and increased Nur77 protein stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Hyperthermia stress activates heat shock protein expression via propyl isomerase 1 regulation with heat shock factor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Pin1 modulates chemo-resistance by up-regulating FoxM1 and the involvements of Wnt/β-catenin signaling pathway in cervical cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Nanomolar inhibitors of the peptidyl prolyl cis/trans isomerase Pin1 from combinatorial peptide libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

An essential role for Pin1 in Xenopus laevis embryonic development revealed by specific inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Modeling breast cancer in vivo and ex vivo reveals an essential role of Pin1 in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Phosphorylation-specific prolyl isomerization: is there an underlying theme?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Pin1 as an anticancer drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

The prolyl isomerase Pin1 functions in mitotic chromosome condensation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Regulation of protein stability by GSK3 mediated phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Regulation of Bruton tyrosine kinase by the peptidylprolyl isomerase Pin1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Structural Basis for High-Affinity Peptide Inhibition of Human Pin1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

FAK phosphorylation by ERK primes ras-induced tyrosine dephosphorylation of FAK mediated by PIN1 and PTP-PEST

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

Ras-induced and extracellular signal-regulated kinase 1 and 2 phosphorylation-dependent isomerization of protein tyrosine phosphatase (PTP)-PEST by PIN1 promotes FAK dephosphorylation by PTP-PEST.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

The isomerase PIN1 controls numerous cancer-driving pathways and is a unique drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-016-0821-X

10.1007/S12272-016-0821-X

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

7 September 2017

0 references

1 reference