(Q38953085)

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Multidrug-resistant cancer cells and cancer stem cells hijack cellular systems to circumvent systemic therapies, can natural products reverse this?

scientific article published on 12 September 2016

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27622244%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

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Europe PubMed Central

Multidrug-resistant cancer cells and cancer stem cells hijack cellular systems to circumvent systemic therapies, can natural products reverse this? (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27622244%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

multiple drug resistance

1 reference

based on heuristic

inferred from title

natural product

1 reference

based on heuristic

inferred from title

neoplastic stem cells

1 reference

based on heuristic

inferred from title

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27622244%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Hendrick Kennedy

3

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Europe PubMed Central

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22 March 2020

author name string

Qian Zhang

1

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Europe PubMed Central

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22 March 2020

publication date

12 September 2016

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22 March 2020

Cellular and Molecular Life Sciences

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22 March 2020

74

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22 March 2020

5

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22 March 2020

777-801

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27622244%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

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1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state

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https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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Colorectal cancer stem cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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Breast cancer stem cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Brain cancer stem cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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Identification of human brain tumour initiating cells

1 reference

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A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

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Direct isolation of human central nervous system stem cells

1 reference

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Isolation of mouse pancreatic ductal progenitor cells expressing CD133 and c-Met by flow cytometric cell sorting

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https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain

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https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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Multidrug resistance genes and p-glycoprotein in the testis of the rat, mouse, Guinea pig, and human

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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Nervous translation, do you get the message? A review of mRNPs, mRNA-protein interactions and translational control within cells of the nervous system

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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Redundancy of biological regulation as the basis of emergence of multidrug resistance.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Multidrug resistance associated proteins in multidrug resistance.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Multidrug resistance related molecules in human and murine lung

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Tissue and cell distribution of the multidrug resistance-associated protein (MRP) in mouse intestine and kidney

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Effects of age on multidrug resistance protein expression and doxorubicin accumulation in cardiac and skeletal muscle.

1 reference

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21 January 2018

Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage

1 reference

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21 January 2018

A multidrug resistance transporter from human MCF-7 breast cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Side population cells and Bcrp1 expression in lung.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

ABCG2: determining its relevance in clinical drug resistance

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

The bioflavonoid kaempferol is an Abcg2 substrate and inhibits Abcg2-mediated quercetin efflux

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https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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Mutations affecting segment number and polarity in Drosophila

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21 January 2018

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

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https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Two patched protein subtypes and a conserved domain of group I proteins that regulates turnover

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Natural paniceins from mediterranean sponge inhibit the multidrug resistance activity of Patched and increase chemotherapy efficiency on melanoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Mechanisms of Hedgehog pathway activation in cancer and implications for therapy.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

The Hedgehog receptor patched functions in multidrug transport and chemotherapy resistance.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

ABCB5 expression and cancer stem cell hypothesis in oral squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Salinomycin overcomes ABC transporter-mediated multidrug and apoptosis resistance in human leukemia stem cell-like KG-1a cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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miR-1915 inhibits Bcl-2 to modulate multidrug resistance by increasing drug-sensitivity in human colorectal carcinoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Targeting apoptosis pathways in cancer stem cells

1 reference

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21 January 2018

Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Nuclear factor-kappaB: the enemy within

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21 January 2018

Targeting inflammatory pathways for prevention and therapy of cancer: short-term friend, long-term foe.

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21 January 2018

Leukemia stem cells and constitutive activation of NF-kappaB.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Leukemic target susceptibility to natural killer cytotoxicity: relationship with BCR-ABL expression

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Constitutive activation of IkappaB kinase alpha and NF-kappaB in prostate cancer cells is inhibited by ibuprofen

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https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth

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21 January 2018

NF-κB in cancer: a matter of life and death

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NF-kappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells

1 reference

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Notch1-induced transformation of RKE-1 cells requires up-regulation of cyclin D1.

1 reference

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21 January 2018

Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling

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Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

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21 January 2018

A role for Wnt signalling in self-renewal of haematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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Wnt signaling in stem and cancer stem cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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A Role for OCT4 in Tumor Initiation of Drug-Resistant Prostate Cancer Cells

1 reference

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Octamer 4 (Oct4) mediates chemotherapeutic drug resistance in liver cancer cells through a potential Oct4-AKT-ATP-binding cassette G2 pathway

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Targeting aldehyde dehydrogenase cancer stem cells in ovarian cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Immunohistochemical staining of cancer stem cell markers in hepatocellular carcinoma

1 reference

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21 January 2018

Single-marker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential Paclitaxel and epirubicin-based chemotherapy for breast cancers.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM, and ALDH1 in colorectal cancer.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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ALDH maintains the stemness of lung adenoma stem cells by suppressing the Notch/CDK2/CCNE pathway

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

High aldehyde dehydrogenase activity enhances stem cell features in breast cancer cells by activating hypoxia-inducible factor-2α.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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Cisplatin-resistant cells in malignant pleural mesothelioma cell lines show ALDH(high)CD44(+) phenotype and sphere-forming capacity.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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DNA damage repair pathways in cancer stem cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

BCR-ABL: a multi-faceted promoter of DNA mutation in chronic myelogeneous leukemia

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https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Prostate cancer stem-like cells proliferate slowly and resist etoposide-induced cytotoxicity via enhancing DNA damage response.

1 reference

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21 January 2018

Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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Quiescence and attenuated DNA damage response promote survival of esophageal cancer stem cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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Inhibition of P-glycoprotein expression and reversal of drug resistance of human hepatoma HepG2 cells by multidrug resistance gene (mdr1) antisense RNA.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

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1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Membrane vesicles from multidrug-resistant human cancer cells contain a specific 150- to 170-kDa protein detected by photoaffinity labeling

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Biochemistry of multidrug resistance mediated by the multidrug transporter

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

New uses for old drugs: pharmacophore-based screening for the discovery of P-glycoprotein inhibitors

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Inhibitory effect of baicalin and baicalein on ovarian cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Anticancer effects of baicalein on hepatocellular carcinoma cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Baicalein reverses hypoxia-induced 5-FU resistance in gastric cancer AGS cells through suppression of glycolysis and the PTEN/Akt/HIF-1α signaling pathway

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Effects of the antioxidant baicalein on the pharmacokinetics of nimodipine in rats: a possible role of P-glycoprotein and CYP3A4 inhibition by baicalein

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Anticancer agent icaritin induces apoptosis through caspase-dependent pathways in human hepatocellular carcinoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Icaritin inhibits JAK/STAT3 signaling and growth of renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Icaritin reverses multidrug resistance of HepG2/ADR human hepatoma cells via downregulation of MDR1 and P‑glycoprotein expression

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Cyclooxygenase-2/prostaglandin E2 pathway mediates icariside II induced apoptosis in human PC-3 prostate cancer cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Herba Epimedii: Anti-Oxidative Properties and Its Medical Implications

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Synthesis and antimultidrug resistance evaluation of icariin and its derivatives

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Changes in the intestinal absorption mechanism of icariin in the nanocavities of cyclodextrins

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Flavonoids: a class of modulators with bifunctional interactions at vicinal ATP- and steroid-binding sites on mouse P-glycoprotein

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Celastraceae sesquiterpenes as a new class of modulators that bind specifically to human P-glycoprotein and reverse cellular multidrug resistance.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Curcumin causes the growth arrest and apoptosis of B cell lymphoma by downregulation of egr-1, c-myc, bcl-XL, NF-kappa B, and p53.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Modulation of human multidrug-resistance MDR-1 gene by natural curcuminoids

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

In vitro antitumor activity of the novel marine agent, ecteinascidin-743 (ET-743, NSC-648766) against human tumors explanted from patients

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

In vitro schedule-dependency of myelotoxicity and cytotoxicity of Ecteinascidin 743 (ET-743).

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Green tea and cancer prevention

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Cancer chemopreventive activity and bioavailability of tea and tea polyphenols

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

The NF-kappaB activation pathways, emerging molecular targets for cancer prevention and therapy

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Inhibition of ultraviolet B-mediated activation of nuclear factor kappaB in normal human epidermal keratinocytes by green tea Constituent (-)-epigallocatechin-3-gallate

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced NF-kappaB activation by tea polyphenols, (-)-epigallocatechin gallate and theaflavins

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Jatrophane diterpenes from Euphorbia mellifera and their activity as P-glycoprotein modulators on multidrug-resistant mouse lymphoma and human colon adenocarcinoma cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Sipholenol A, a marine-derived sipholane triterpene, potently reverses P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Marine sponge-derived sipholane triterpenoids reverse P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Inhibition of leukemic cell growth by a novel anti-cancer drug (GUT-70) from calophyllum brasiliense that acts by induction of apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Polyaromatic alkaloids from marine invertebrates as cytotoxic compounds and inhibitors of multidrug resistance caused by P-glycoprotein

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Drug resistance associates with activation of Nrf2 in MCF-7/DOX cells, and wogonin reverses it by down-regulating Nrf2-mediated cellular defense response

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Wogonin reverses multi-drug resistance of human myelogenous leukemia K562/A02 cells via downregulation of MRP1 expression by inhibiting Nrf2/ARE signaling pathway

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Wogonin potentiates the antitumor action of etoposide and ameliorates its adverse effects

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Reversing effect of agosterol A, a spongean sterol acetate, on multidrug resistance in human carcinoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Reversal of breast cancer resistance protein–mediated drug resistance by tryprostatin A

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Protective effect of genistein isolated from Hydrocotyle sibthorpioides on hepatic injury and fibrosis induced by chronic alcohol in rats

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Three new compounds from Aspergillus terreus PT06-2 grown in a high salt medium

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Asperjinone, a nor-neolignan, and terrein, a suppressor of ABCG2-expressing breast cancer cells, from thermophilic Aspergillus terreus

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

The marine-derived fungal metabolite, terrein, inhibits cell proliferation and induces cell cycle arrest in human ovarian cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Cytotoxic and Insecticidal Activities of Derivatives of Harmine, a Natural Insecticidal Component Isolated from Peganum harmala

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Harmine induces apoptosis and inhibits tumor cell proliferation, migration and invasion through down-regulation of cyclooxygenase-2 expression in gastric cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

The beta-carboline alkaloid harmine inhibits BCRP and can reverse resistance to the anticancer drugs mitoxantrone and camptothecin in breast cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Lamellarin O, a pyrrole alkaloid from an Australian marine sponge, Ianthella sp., reverses BCRP mediated drug resistance in cancer cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Inhibition of P-glycoprotein by orange juice components, polymethoxyflavones in adriamycin-resistant human myelogenous leukemia (K562/ADM) cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Multidrug resistance reversal and apoptosis induction in human colon cancer cells by some flavonoids present in citrus plants.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Ingredients in fruit juices interact with dasatinib through inhibition of BCRP: a new mechanism of beverage-drug interaction

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Secalonic acid D reduced the percentage of side populations by down-regulating the expression of ABCG2.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Hepatobiliary excretion of berberine

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Berberine-antiproliferative activity in vitro and induction of apoptosis/necrosis of the U937 and B16 cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Epithelial-to-mesenchymal transition markers to predict response of Berberine in suppressing lung cancer invasion and metastasis

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Berberine diminishes side population and down-regulates stem cell-associated genes in the pancreatic cancer cell lines PANC-1 and MIA PaCa-2.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Targeting cancer stem cells by curcumin and clinical applications

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Targeting breast stem cells with the cancer preventive compounds curcumin and piperine

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Curcumin targets breast cancer stem-like cells with microtentacles that persist in mammospheres and promote reattachment

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Curcumin inhibits breast cancer stem cell migration by amplifying the E-cadherin/β-catenin negative feedback loop

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Difluorinated-curcumin (CDF): a novel curcumin analog is a potent inhibitor of colon cancer stem-like cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Underlying mechanism of quercetin-induced cell death in human glioma cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Quercetin inhibits human breast cancer cell proliferation and induces apoptosis via Bcl-2 and Bax regulation

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Quercetin in elimination of tumor initiating stem-like and mesenchymal transformation property in head and neck cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Quercetin suppresses drug-resistant spheres via the p38 MAPK-Hsp27 apoptotic pathway in oral cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Resveratrol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Resveratrol Impedes the Stemness, Epithelial-Mesenchymal Transition, and Metabolic Reprogramming of Cancer Stem Cells in Nasopharyngeal Carcinoma through p53 Activation

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Resveratrol inhibits cisplatin-induced epithelial-to-mesenchymal transition in ovarian cancer cell lines

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Resveratrol inhibits breast cancer stem-like cells and induces autophagy via suppressing Wnt/β-catenin signaling pathway

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Identification of selective inhibitors of cancer stem cells by high-throughput screening

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Inhibition of the autophagic flux by salinomycin in breast cancer stem-like/progenitor cells interferes with their maintenance

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Salinomycin inhibits the tumor growth of glioma stem cells by selectively suppressing glioma-initiating cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Roles of Wnt/β-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Salinomycin inhibits osteosarcoma by targeting its tumor stem cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

The Structure of Mithramycin Reinvestigated

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Mithramycin represses basal and cigarette smoke-induced expression of ABCG2 and inhibits stem cell signaling in lung and esophageal cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Regulation of Inflammation by the NF-κB Pathway in Ovarian Cancer Stem Cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Galiellalactone is a direct inhibitor of the transcription factor STAT3 in prostate cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Galiellalactone inhibits stem cell-like ALDH-positive prostate cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Guggulsterone sensitizes glioblastoma cells to Sonic hedgehog inhibitor SANT-1 induced apoptosis in a Ras/NFκB dependent manner

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Telomestatin impairs glioma stem cell survival and growth through the disruption of telomeric G-quadruplex and inhibition of the proto-oncogene, c-Myb.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Specific targeting of neurotoxic side effects and pharmacological profile of the novel cancer stem cell drug salinomycin in mice

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

In vitro effect of quercetin on human gastric carcinoma: targeting cancer cells death and MDR.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Quercetin regulates β-catenin signaling and reduces the migration of triple negative breast cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Antiproliferative and pro-apoptotic effects of quercetin on human pancreatic carcinoma cell lines EPP85-181P and EPP85-181RDB.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Prostate cancer stem cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2362-3

21 January 2018

Characterization of the drug resistance and transport properties of multidrug resistance protein 6 (MRP6, ABCC6).

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional and molecular characterisation of mammary side population cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of members of the multidrug resistance protein family in human term placenta

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quercetin induces cell cycle arrest and apoptosis in CD133(+) cancer stem cells of human colorectal HT29 cancer cell line and enhances anticancer effects of doxorubicin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Colon cancer stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human ATP-binding cassette (ABC) transporter superfamily.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new sesquiterpene ester from Celastrus orbiculatus reversing multidrug resistance in cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural determinants of phenoxazine type compounds required to modulate the accumulation of vinblastine and vincristine in multidrug-resistant cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulators of Multidrug Resistance: Preclinical Studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human ATP-binding cassette (ABC) transporter superfamily

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Salinomycin can effectively kill ALDH(high) stem-like cells on gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sonic Hedgehog promotes multiple drug resistance by regulation of drug transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tangeretin, a citrus flavonoid, inhibits PGDF-BB-induced proliferation and migration of aortic smooth muscle cells by blocking AKT activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary polyphenol quercetin targets pancreatic cancer stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis and update of the human aldehyde dehydrogenase (ALDH) gene family

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ecteinascidin-743, a new marine natural product with potent antitumor activity on human ovarian carcinoma xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overcoming multidrug drug resistance in P-glycoprotein/MDR1-overexpressing cell lines by ecteinascidin 743.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resveratrol inhibits insulin secretion from rat pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lung cancer tumorigenicity and drug resistance are maintained through ALDH(hi)CD44(hi) tumor initiating cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The isolation, structure and absolute configuration of secalonic acid D, the toxic metabolite of Penicillium oxalicum

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Escape from stress granule sequestration: another way to drug resistance?

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin and epigallocatechin gallate inhibit the cancer stem cell phenotype via down-regulation of STAT3-NFκB signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anticancer potential of curcumin: preclinical and clinical studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATP binding cassette multidrug transporters limit the anti-HIV activity of zidovudine and indinavir in infected human macrophages.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Baicalein increases the cytotoxicity of cisplatin by enhancing gap junction intercellular communication

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27622244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00018-016-2362-3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27622244%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27622244%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

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