(Q38956273)

7 September 2017

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title

Pediatric T-cell acute lymphoblastic leukemia (English)

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7 September 2017

Kristina Karrman

1

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7 September 2017

Bertil Johansson

series ordinal

2

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7 September 2017

publication date

16 September 2016

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Genes, Chromosomes and Cancer

7 September 2017

published in

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7 September 2017

volume

56

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7 September 2017

issue

2

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7 September 2017

page(s)

89-116

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An X-linked tumor suppressor in T-ALL.

7 September 2017

cites work

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NOTCH is a key regulator of human T-cell acute leukemia initiating cell activity

21 January 2018

1 reference

Comprehensive analysis of transcriptome variation uncovers known and novel driver events in T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

NOTCH1 activation clinically antagonizes the unfavorable effect of PTEN inactivation in BFM-treated children with precursor T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia.

21 January 2018

1 reference

Symptoms of childhood acute lymphoblastic leukemia: red flags to recognize leukemia in daily practice

21 January 2018

1 reference

Cell of origin strongly influences genetic selection in a mouse model of T-ALL

21 January 2018

1 reference

Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency

21 January 2018

1 reference

Cryptic XPO1-MLLT10 translocation is associated with HOXA locus deregulation in T-ALL.

21 January 2018

1 reference

Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)

21 January 2018

1 reference

Promoter DNA methylation pattern identifies prognostic subgroups in childhood T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

DNA Methylation Adds Prognostic Value to Minimal Residual Disease Status in Pediatric T-Cell Acute Lymphoblastic Leukemia

21 January 2018

1 reference

New MLLT10 gene recombinations in pediatric T-acute lymphoblastic leukemia.

21 January 2018

1 reference

Gene therapy for Wiskott-Aldrich syndrome--long-term efficacy and genotoxicity

21 January 2018

1 reference

Activating NOTCH1 mutations predict favorable early treatment response and long-term outcome in childhood precursor T-cell lymphoblastic leukemia.

21 January 2018

1 reference

Chromothripsis-like patterns are recurring but heterogeneously distributed features in a survey of 22,347 cancer genome screens

21 January 2018

1 reference

Molecular cytogenetic study of 126 unselected T-ALL cases reveals high incidence of TCRbeta locus rearrangements and putative new T-cell oncogenes

21 January 2018

1 reference

Clinical significance of HOX11L2 expression linked to t(5;14)(q35;q32), of HOX11 expression, and of SIL-TAL fusion in childhood T-cell malignancies: results of EORTC studies 58881 and 58951

21 January 2018

1 reference

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

21 January 2018

1 reference

Systematic screen for tyrosine kinase rearrangements identifies a novel C6orf204-PDGFRB fusion in a patient with recurrent T-ALL and an associated myeloproliferative neoplasm

21 January 2018

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The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children.

21 January 2018

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Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse

21 January 2018

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NUP214-ABL1 positive T-cell acute lymphoblastic leukemia patient shows an initial favorable response to imatinib therapy post relapse.

21 January 2018

1 reference

Early T-cell precursor acute lymphoblastic leukaemia in children treated in AIEOP centres with AIEOP-BFM protocols: a retrospective analysis

21 January 2018

1 reference

Acute leukemias of different lineages have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation.

21 January 2018

1 reference

Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia

21 January 2018

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Complete morphologic and molecular remission after introduction of dasatinib in the treatment of a pediatric patient with t-cell acute lymphoblastic leukemia and ABL1 amplification.

21 January 2018

1 reference

Clinical features and outcome of SIL/TAL1-positive T-cell acute lymphoblastic leukemia in children and adolescents: a 10-year experience of the AIEOP group

21 January 2018

1 reference

Fusion of EML1 to ABL1 in T-cell acute lymphoblastic leukemia with cryptic t(9;14)(q34;q32).

21 January 2018

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Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

John Hughes Bennett, Rudolph Virchow... and Alfred Donné: the first description of leukemia

21 January 2018

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The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia

21 January 2018

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Aetiology of childhood leukaemia

21 January 2018

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Kinetics of mature T-cell development in the thymus

21 January 2018

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NOTCH1 mutation can be an early, prenatal genetic event in T-ALL.

21 January 2018

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Tcrδ translocations that delete the Bcl11b haploinsufficient tumor suppressor gene promote atm-deficient T cell acute lymphoblastic leukemia

21 January 2018

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TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

21 January 2018

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Combined translocation with ZNF198-FGFR1 gene fusion and deletion of potential tumor suppressors in a myeloproliferative disorder

21 January 2018

1 reference

The history of cancer epigenetics

21 January 2018

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Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

21 January 2018

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Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma

21 January 2018

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Screening for leukemia- and clone-specific markers at birth in children with T-cell precursor ALL suggests a predominantly postnatal origin.

21 January 2018

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Prognostic implications of mutations in NOTCH1 and FBXW7 in childhood T-ALL treated according to the NOPHO ALL-1992 and ALL-2000 protocols

21 January 2018

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Backtracking leukemia to birth: identification of clonotypic gene fusion sequences in neonatal blood spots

21 January 2018

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Long-term results of the children's cancer group studies for childhood acute lymphoblastic leukemia 1983-2002: a Children's Oncology Group Report

21 January 2018

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Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types

21 January 2018

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Increased expression of miR-221 is associated with shorter overall survival in T-cell acute lymphoid leukemia.

21 January 2018

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Antibiotic use from conception to diagnosis of child leukaemia as compared to the background population: A nested case-control study

21 January 2018

1 reference

Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

Cytogenetics and molecular genetics of T-cell acute lymphoblastic leukemia: from thymocyte to lymphoblast

21 January 2018

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Heterogeneous patterns of amplification of the NUP214-ABL1 fusion gene in T-cell acute lymphoblastic leukemia.

21 January 2018

1 reference

Infection, immune responses and the aetiology of childhood leukaemia

21 January 2018

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Identification of an ETV6-ABL2 fusion transcript in combination with an ETV6 point mutation in a T-cell acute lymphoblastic leukaemia cell line.

21 January 2018

1 reference

High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

Absence of biallelic TCRgamma deletion predicts early treatment failure in pediatric T-cell acute lymphoblastic leukemia

21 January 2018

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Inactivation of LEF1 in T-cell acute lymphoblastic leukemia

21 January 2018

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The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia

21 January 2018

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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

21 January 2018

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Disruption of the RanBP17/Hox11L2 region by recombination with the TCRdelta locus in acute lymphoblastic leukemias with t(5;14)(q34;q11).

21 January 2018

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Increased post-induction intensification improves outcome in children and adolescents with a markedly elevated white blood cell count (≥200 × 10(9) /l) with T cell acute lymphoblastic leukaemia but not B cell disease: a report from the Children's On

21 January 2018

1 reference

Early T-cell precursor acute lymphoblastic leukaemia

21 January 2018

1 reference

Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis

21 January 2018

1 reference

Frequency and clinical significance of cytogenetic abnormalities in pediatric T-lineage acute lymphoblastic leukemia: a report from the Children's Cancer Group

21 January 2018

1 reference

A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia

21 January 2018

1 reference

Age- and sex-specific incidence of childhood leukemia by immunophenotype in the Nordic countries

21 January 2018

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Activation of proto-oncogenes by disruption of chromosome neighborhoods.

21 January 2018

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Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia.

21 January 2018

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The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes.

21 January 2018

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Improved survival for children and adolescents with acute lymphoblastic leukemia between 1990 and 2005: a report from the children's oncology group

21 January 2018

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First description of the t(10;11)(q22;q23)/MLL-TET1 translocation in a T-cell lymphoblastic lymphoma, with subsequent lineage switch to acute myelomonocytic myeloid leukemia

21 January 2018

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Impact of NOTCH1/FBXW7 mutations on outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on the MRC UKALL 2003 trial.

21 January 2018

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Mechanisms of epigenetic deregulation in lymphoid neoplasms

21 January 2018

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Prognostic value of miR-16 expression in childhood acute lymphoblastic leukemia relationships to normal and malignant lymphocyte proliferation

21 January 2018

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Clustering of breakpoints on chromosome 10 in acute T-cell leukemias with the t(10;14) chromosome translocation

21 January 2018

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Clinical and cytogenetic features of a population-based consecutive series of 285 pediatric T-cell acute lymphoblastic leukemias: rare T-cell receptor gene rearrangements are associated with poor outcome.

21 January 2018

1 reference

The t(X;7)(q22;q34) in paediatric T-cell acute lymphoblastic leukaemia results in overexpression of the insulin receptor substrate 4 gene through illegitimate recombination with the T-cell receptor beta locus.

21 January 2018

1 reference

Deep sequencing and SNP array analyses of pediatric T-cell acute lymphoblastic leukemia reveal NOTCH1 mutations in minor subclones and a high incidence of uniparental isodisomies affecting CDKN2A

21 January 2018

1 reference

Molecular involvement of the pvt-1 locus in a gamma/delta T-cell leukemia bearing a variant t(8;14)(q24;q11) translocation

21 January 2018

1 reference

Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray

21 January 2018

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Infections and immune factors in cancer: the role of epidemiology

21 January 2018

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Genomic runs of homozygosity record population history and consanguinity

21 January 2018

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The role of gene dosage and genetic transpositions in carcinogenesis

21 January 2018

1 reference

Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

Notch in T-ALL: new players in a complex disease.

21 January 2018

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The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL-BFM 2000 protocol can be separated from FBXW7 loss of function

21 January 2018

1 reference

Frequency and clinical relevance of DNA microsatellite alterations of the CDKN2A/B, ATM and p53 gene loci: a comparison between pediatric precursor T-cell lymphoblastic lymphoma and T-cell lymphoblastic leukemia

21 January 2018

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Characterization of the MLL partner gene AF15q14 involved in t(11;15)(q23;q14).

21 January 2018

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Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia.

21 January 2018

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Pediatric T-cell lymphoblastic leukemia evolves into relapse by clonal selection, acquisition of mutations and promoter hypomethylation

21 January 2018

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Linking genomic lesions with minimal residual disease improves prognostic stratification in children with T-cell acute lymphoblastic leukaemia.

21 January 2018

1 reference

A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

21 January 2018

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Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia

21 January 2018

1 reference

The consequences of uniparental disomy and copy number neutral loss-of-heterozygosity during human development and cancer

21 January 2018

1 reference

Extensive molecular mapping of TCRα/δ- and TCRβ-involved chromosomal translocations reveals distinct mechanisms of oncogene activation in T-ALL.

21 January 2018

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Translocations among antibody genes in human cancer

21 January 2018

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Childhood near-tetraploid acute lymphoblastic leukemia: an EGIL study on 36 cases.

21 January 2018

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EPHA7, a new target gene for 6q deletion in T-cell lymphoblastic lymphomas

21 January 2018

1 reference

Patterns and frequencies of acquired and constitutional uniparental isodisomies in pediatric and adult B-cell precursor acute lymphoblastic leukemia.

21 January 2018

1 reference

The indicative effect of Notch1 expression for the prognosis of T-cell acute lymphocytic leukemia: a systematic review

21 January 2018

1 reference

Activation of HOX11L2 by juxtaposition with 3'-BCL11B in an acute lymphoblastic leukemia cell line (HPB-ALL) with t(5;14)(q35;q32.2).

21 January 2018

1 reference

Pathogenesis and consequences of uniparental disomy in cancer

21 January 2018

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The TAL1 complex targets the FBXW7 tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia

21 January 2018

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Oncogene regulation. An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element

21 January 2018

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Impact of complex NOTCH1 mutations on survival in paediatric T-cell leukaemia.

21 January 2018

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Distinctive genotypes in infants with T-cell acute lymphoblastic leukaemia.

21 January 2018

1 reference

T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics, and outcome from the large randomized prospective trial (UKALL XII/ECOG 2993)

21 January 2018

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A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL).

21 January 2018

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The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal

21 January 2018

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The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein

21 January 2018

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lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif

21 January 2018

1 reference

The emerging complexity of gene fusions in cancer

21 January 2018

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MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia

21 January 2018

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MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

A novel gene, FGA7, is fused to RUNX1/AML1 in a t(4;21)(q28;q22) in a patient with T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

IMMUNOLOGICAL FUNCTION OF THE THYMUS

21 January 2018

1 reference

The golden anniversary of the thymus

21 January 2018

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Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

21 January 2018

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Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia.

21 January 2018

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Site- and allele-specific polycomb dysregulation in T-cell leukaemia

21 January 2018

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Receptor editing in lymphocyte development and central tolerance.

21 January 2018

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Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia

21 January 2018

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ETV6-ARNT fusion in a patient with childhood T lymphoblastic leukemia

21 January 2018

1 reference

Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia

21 January 2018

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Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

21 January 2018

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Fusion of NUP98 and the SET binding protein 1 (SETBP1) gene in a paediatric acute T cell lymphoblastic leukaemia with t(11;18)(p15;q12).

21 January 2018

1 reference

Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia

21 January 2018

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Chromosome abnormalities in T-cell acute lymphoblastic leukemia in Korea.

21 January 2018

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Aberrant TAL1 activation is mediated by an interchromosomal interaction in human T-cell acute lymphoblastic leukemia

21 January 2018

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High hyperdiploid childhood acute lymphoblastic leukemia

21 January 2018

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Epigenetics in T-cell acute lymphoblastic leukemia

21 January 2018

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Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse

21 January 2018

1 reference

Leukaemia - a brief historical review from ancient times to 1950.

21 January 2018

1 reference

Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL.

21 January 2018

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Treating childhood acute lymphoblastic leukemia without cranial irradiation

21 January 2018

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A 50-year journey to cure childhood acute lymphoblastic leukemia

21 January 2018

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Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration

21 January 2018

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Activity of tyrosine kinase inhibitors against human NUP214-ABL1-positive T cell malignancies

21 January 2018

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In vitro drug resistance and prognostic impact of p16INK4A/P15INK4B deletions in childhood T-cell acute lymphoblastic leukaemia

21 January 2018

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Homozygous deletions of CDKN2A caused by alternative mechanisms in various human cancer cell lines.

21 January 2018

1 reference

High-resolution genomic profiling of childhood T-ALL reveals frequent copy-number alterations affecting the TGF-beta and PI3K-AKT pathways and deletions at 6q15-16.1 as a genomic marker for unfavorable early treatment response

21 January 2018

1 reference

NUP98 rearrangements in hematopoietic malignancies: a study of the Groupe Francophone de Cytogénétique Hématologique.

21 January 2018

1 reference

New Approaches to Target T-ALL.

21 January 2018

1 reference

Characterization of a set of tumor suppressor microRNAs in T cell acute lymphoblastic leukemia

21 January 2018

1 reference

Long-term results of NOPHO ALL-92 and ALL-2000 studies of childhood acute lymphoblastic leukemia

21 January 2018

1 reference

High concordance of subtypes of childhood acute lymphoblastic leukemia within families: lessons from sibships with multiple cases of leukemia.

21 January 2018

1 reference

Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study.

21 January 2018

1 reference

Pediatric leukemia predisposition syndromes: clues to understanding leukemogenesis

21 January 2018

1 reference

An evolutionary perspective on the mechanisms of immunosenescence

21 January 2018

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Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk

21 January 2018

1 reference

Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia

21 January 2018

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21 January 2018

Cancer statistics, 2012

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A fluorescence in situ hybridization map of 6q deletions in acute lymphocytic leukemia: identification and analysis of a candidate tumor suppressor gene

21 January 2018

1 reference

HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL).

21 January 2018

1 reference

Massive genomic rearrangement acquired in a single catastrophic event during cancer development

21 January 2018

1 reference

Various types of rearrangements target TLX3 locus in T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

Late recurrence of childhood T-cell acute lymphoblastic leukemia frequently represents a second leukemia rather than a relapse: first evidence for genetic predisposition.

21 January 2018

1 reference

Molecular cytogenetic analysis of the breakpoint region at 6q21-22 in T-cell lymphoma/leukemia cell lines

21 January 2018

1 reference

Analysis of the t(6;11)(q27;q23) in leukemia shows a consistent breakpoint in AF6 in three patients and in the ML-2 cell line

21 January 2018

1 reference

Predicting relapse risk in childhood acute lymphoblastic leukaemia

21 January 2018

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Risk group assignment differs for children and adults 1-45 yr with acute lymphoblastic leukemia treated by the NOPHO ALL-2008 protocol

21 January 2018

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21 January 2018

WT1 mutations in T-ALL

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The NOTCH signaling pathway: role in the pathogenesis of T-cell acute lymphoblastic leukemia and implication for therapy

21 January 2018

1 reference

The clonal evolution of leukemic stem cells in T-cell acute lymphoblastic leukemia.

21 January 2018

1 reference

Germline genomic variants associated with childhood acute lymphoblastic leukemia

21 January 2018

1 reference

Genome-wide mapping and characterization of Notch-regulated long noncoding RNAs in acute leukemia

21 January 2018

1 reference

Triggering the TCR Developmental Checkpoint Activates a Therapeutically Targetable Tumor Suppressive Pathway in T-cell Leukemia.

21 January 2018

1 reference

Chromosomal translocations joining LCK and TCRB loci in human T cell leukemia

21 January 2018

1 reference

Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL.

21 January 2018

1 reference

A meta-analysis of the association between day-care attendance and childhood acute lymphoblastic leukaemia

21 January 2018

1 reference

High white blood cell count at diagnosis of childhood acute lymphoblastic leukaemia: biological background and prognostic impact. Results from the NOPHO ALL-92 and ALL-2000 studies

21 January 2018

1 reference

The epigenetic landscape of T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

Minimal residual disease diagnostics in acute lymphoblastic leukemia: need for sensitive, fast, and standardized technologies

21 January 2018

1 reference

Prognostic significance of molecular-cytogenetic abnormalities in pediatric T-ALL is not explained by immunophenotypic differences.

21 January 2018

1 reference

Molecular-genetic insights in paediatric T-cell acute lymphoblastic leukaemia

21 January 2018

1 reference

The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

PHF6 mutations in T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

ETV6 mutations in early immature human T cell leukemias

21 January 2018

1 reference

The molecular basis of T cell acute lymphoblastic leukemia

21 January 2018

1 reference

Dexamethasone-based therapy for childhood acute lymphoblastic leukaemia: results of the prospective Dutch Childhood Oncology Group (DCOG) protocol ALL-9 (1997-2004).

21 January 2018

1 reference

Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

21 January 2018

Cancer genome landscapes

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Childhood leukaemia following medical diagnostic exposure to ionizing radiation in utero or after birth.

21 January 2018

1 reference

Long noncoding RNA signatures define oncogenic subtypes in T-cell acute lymphoblastic leukemia.

21 January 2018

1 reference

The t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia activates the BHLHB1 gene

21 January 2018

1 reference

LncRNA NALT interaction with NOTCH1 promoted cell proliferation in pediatric T cell acute lymphoblastic leukemia

21 January 2018

1 reference

The Functions of Histone Modification Enzymes in Cancer

21 January 2018

1 reference

The kinase inhibitor TKI258 is active against the novel CUX1-FGFR1 fusion detected in a patient with T-lymphoblastic leukemia/lymphoma and t(7;8)(q22;p11).

21 January 2018

1 reference

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

21 January 2018

1 reference

Detection of minimal residual disease identifies differences in treatment response between T-ALL and precursor B-ALL.

21 January 2018

1 reference

Micro-RNA-16 expression in paraffin-embedded specimen correlates with overall survival of T-lymphoblastic lymphoma/leukemia

21 January 2018

1 reference

TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia

21 January 2018

1 reference

Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations

21 January 2018

1 reference

Absence of biallelic TCRγ deletion predicts induction failure and poorer outcomes in childhood T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

BCR-PDGFRA fusion in a T lymphoblastic leukemia/lymphoma.

21 January 2018

1 reference

Genetic mutational profiling analysis of T cell acute lymphoblastic leukemia reveal mutant FBXW7 as a prognostic indicator for inferior survival

21 January 2018

1 reference

The frequency and prognostic impact of dic(9;20)(p13.2;q11.2) in childhood B-cell precursor acute lymphoblastic leukemia: results from the NOPHO ALL-2000 trial.

21 January 2018

1 reference

Characterization of leukemias with ETV6-ABL1 fusion

21 January 2018

1 reference

Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

21 January 2018

1 reference

NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols

21 January 2018

1 reference

Cancer in siblings of children with cancer in the Nordic countries: a population-based cohort study

21 January 2018

1 reference

8p11 myeloproliferative syndrome with BCR-FGFR1 rearrangement presenting with T-lymphoblastic lymphoma and bone marrow stromal cell proliferation: A case report and review of the literature

21 January 2018

1 reference

Genetic profile of T-cell acute lymphoblastic leukemias with MYC translocations

21 January 2018

1 reference

Interphase fluorescent in situ hybridization deletion analysis of the 9p21 region and prognosis in childhood acute lymphoblastic leukaemia (ALL): results from a prospective analysis of 519 Nordic patients treated according to the NOPHO-ALL 2000 proto

21 January 2018

1 reference

Occurrence of identical NOTCH1 mutation in non-twinned sisters with T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

Leukemia-associated NF1 inactivation in patients with pediatric T-ALL and AML lacking evidence for neurofibromatosis

21 January 2018

1 reference

7 January 2021

Impact of genotype on survival of children with T-cell acute lymphoblastic leukemia treated according to the French protocol FRALLE-93: the effect of TLX3/HOX11L2 gene expression on outcome

1 reference

7 January 2021

T-cell lymphoblastic lymphoma shows differences and similarities with T-cell acute lymphoblastic leukemia by genomic and gene expression analyses

1 reference

7 January 2021

Novel non-TCR chromosome translocations t(3;11)(q25;p13) and t(X;11)(q25;p13) activating LMO2 by juxtaposition with MBNL1 and STAG2

1 reference

7 January 2021

Identification of the novel AML1 fusion partner gene, LAF4, a fusion partner of MLL, in childhood T-cell acute lymphoblastic leukemia with t(2;21)(q11;q22) by bubble PCR method for cDNA

1 reference

7 January 2021

Cyclin D2 dysregulation by chromosomal translocations to TCR loci in T-cell acute lymphoblastic leukemias

1 reference

7 January 2021

Different chromosomal breakpoints impact the level of LMO2 expression in T-ALL

1 reference

7 January 2021

A new genetic concept: uniparental disomy and its potential effect, isodisomy

1 reference

7 January 2021

Deregulation of c-myc by translocation of the alpha-locus of the T-cell receptor in T-cell leukemias

1 reference

7 January 2021

NOTCH1 mutations are associated with favourable long-term prognosis in paediatric T-cell acute lymphoblastic leukaemia: a retrospective study of patients treated on BCH-2003 and CCLG-2008 protocol in China

1 reference

7 January 2021

T-cell acute lymphoblastic leukemias with a t(8;14) possibly involving a c-myc locus and T-cell-receptor alpha-chain genes

1 reference

7 January 2021

Impact of PTEN abnormalities on outcome in pediatric patients with T-cell acute lymphoblastic leukemia treated on the MRC UKALL2003 trial

1 reference

7 January 2021

Primary vs. secondary neoplasia-associated chromosomal abnormalities--balanced rearrangements vs. genomic imbalances?

1 reference

7 January 2021

Immunoglobulin/T-cell receptor gene rearrangements in the diagnostic paradigm of pediatric patients with T-cell acute lymphoblastic leukemia

1 reference

7 January 2021

Notch-1 mutations are secondary events in some patients with T-cell acute lymphoblastic leukemia

1 reference

7 January 2021

PTEN microdeletions in T-cell acute lymphoblastic leukemia are caused by illegitimate RAG-mediated recombination events

1 reference

7 January 2021

Outcome for children and young people with Early T-cell precursor acute lymphoblastic leukaemia treated on a contemporary protocol, UKALL 2003

1 reference

7 January 2021

Clinical importance of lymphoblasts with T markers in childhood acute leukemia

1 reference

7 January 2021

A second NOTCH1 chromosome rearrangement: t(9;14)(q34.3;q11.2) in T-cell neoplasia

1 reference

7 January 2021

T cell receptor gamma (TCRG) gene rearrangements in T cell acute lymphoblastic leukemia refelct 'end-stage' recombinations: implications for minimal residual disease monitoring

1 reference

7 January 2021

The cryptic chromosomal deletion del(11)(p12p13) as a new activation mechanism of LMO2 in pediatric T-cell acute lymphoblastic leukemia

1 reference

7 January 2021

Monoallelic or biallelic LMO2 expression in relation to the LMO2 rearrangement status in pediatric T-cell acute lymphoblastic leukemia

1 reference

7 January 2021

Adult T-cell acute lymphoblastic leukemia: biologic profile at presentation and correlation with response to induction treatment in patients enrolled in the GIMEMA LAL 0496 protocol

1 reference

7 January 2021

Microarray detection of multiple recurring submicroscopic chromosomal aberrations in pediatric T-cell acute lymphoblastic leukemia

1 reference

7 January 2021

Detection of ETV6 gene rearrangements in adult acute lymphoblastic leukemia

1 reference

7 January 2021

Identifiers

DOI

10.1002/GCC.22416

1 reference

7 September 2017

1 reference