(Q39024897)

8 September 2017

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title

Autophagy in chronic liver diseases: the two faces of Janus (English)

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8 September 2017

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chronic liver disease

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3

Sophie Lotersztajn

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Philippe Gual

object named as

Philippe Gual

series ordinal

1

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author name string

Hélène Gilgenkrantz

series ordinal

2

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8 September 2017

publication date

30 November 2016

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American Journal of Physiology - Cell Physiology

8 September 2017

published in

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8 September 2017

volume

312

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8 September 2017

issue

3

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8 September 2017

page(s)

C263-C273

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Chaperone-mediated autophagy in protein quality control

8 September 2017

cites work

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Progenitor cell expansion and impaired hepatocyte regeneration in explanted livers from alcoholic hepatitis

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Autophagy in malignant transformation and cancer progression

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Alcoholic liver disease: pathogenesis and new therapeutic targets

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Autophagy is a regulator of TGF-β1-induced fibrogenesis in primary human atrial myofibroblasts

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New insights into liver regeneration.

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Targeting autophagy potentiates chemotherapy-induced apoptosis and proliferation inhibition in hepatocarcinoma cells

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Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues.

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Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression.

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Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells

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TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis

21 January 2018

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Autophagy is required for CSF-1-induced macrophagic differentiation and acquisition of phagocytic functions.

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Altered lipid content inhibits autophagic vesicular fusion

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Chaperone-mediated autophagy is required for tumor growth

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Autophagy and non-alcoholic fatty liver disease.

21 January 2018

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Punctate LC3B expression is a common feature of solid tumors and associated with proliferation, metastasis, and poor outcome

21 January 2018

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Autophagy inhibition improves chemosensitivity in BRAF(V600E) brain tumors

21 January 2018

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Atg5-mediated autophagy deficiency in proximal tubules promotes cell cycle G2/M arrest and renal fibrosis

21 January 2018

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Autophagy promotes hepatocellular carcinoma cell invasion through activation of epithelial-mesenchymal transition

21 January 2018

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Macrophage autophagy plays a protective role in advanced atherosclerosis

21 January 2018

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Amiodarone as an autophagy promoter reduces liver injury and enhances liver regeneration and survival in mice after partial hepatectomy

21 January 2018

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Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice

21 January 2018

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Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization

21 January 2018

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Macrophage autophagy protects against liver fibrosis in mice

21 January 2018

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21 January 2018

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21 January 2018

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Cellular mechanisms of tissue fibrosis. 5. Novel insights into liver fibrosis

21 January 2018

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Pathophysiology of NASH: perspectives for a targeted treatment

21 January 2018

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Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.

21 January 2018

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Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: The central role of nontriglyceride fatty acid metabolites

21 January 2018

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Nrf2 promotes the development of fibrosis and tumorigenesis in mice with defective hepatic autophagy

21 January 2018

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Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells

21 January 2018

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Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice

21 January 2018

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Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

21 January 2018

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New concepts in liver regeneration

21 January 2018

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Nonalcoholic fatty liver disease: a systematic review

21 January 2018

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p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming

21 January 2018

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Deficient chaperone-mediated autophagy in liver leads to metabolic dysregulation

21 January 2018

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Loss of hepatic chaperone-mediated autophagy accelerates proteostasis failure in aging

21 January 2018

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TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop

21 January 2018

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The MAP1-LC3 conjugation system is involved in lipid droplet formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

Autophagy regulates lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

Characterisation of the liver progenitor cell niche in liver diseases: potential involvement of Wnt and Notch signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

Autophagy-deficient mice develop multiple liver tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

Clonal tracing of Sox9+ liver progenitors in mouse oval cell injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

Acute and Chronic Ethanol Administration Differentially Modulate Hepatic Autophagy and Transcription Factor EB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

Suppression of autophagy during liver regeneration impairs energy charge and hepatocyte senescence in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

Sirolimus-based immunosuppression is associated with increased survival after liver transplantation for hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

Non-alcoholic steatohepatitis in morbidly obese patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

Overactivation of S6 kinase 1 as a cause of human insulin resistance during increased amino acid availability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

Links between hepatic fibrosis, ductular reaction, and progenitor cell expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

Autophagy-deficiency in hepatic progenitor cells leads to the defects of stemness and enhances susceptibility to neoplastic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

Adult hepatocytes are generated by self-duplication rather than stem cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

Epithelial cell adhesion molecule (EpCAM) marks hepatocytes newly derived from stem/progenitor cells in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

A role for mitochondria in NLRP3 inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00295.2016

10.1152/AJPCELL.00295.2016

21 January 2018

Identifiers

DOI

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8 September 2017

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