(Q39175672)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27861808%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

title

Peptidomic analysis of type 1 diabetes associated HLA-DQ molecules and the impact of HLA-DM on peptide repertoire editing (English)

1 reference

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27 March 2020

0 references

2

1 reference

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27 March 2020

Kuan Y Chang

4

1 reference

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27 March 2020

author name string

Zemin Zhou

1

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27 March 2020

Hernando Escobar

3

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27 March 2020

Adam P Barker

5

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27 March 2020

Alan L Rockwood

6

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27 March 2020

Julio C Delgado

7

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27 March 2020

Xiao He

8

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27 March 2020

Peter E Jensen

9

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27 March 2020

language of work or name

English

0 references

publication date

13 December 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27861808%20AND%20SRC:MED&resulttype=core&format=json

European Journal of Immunology

27 March 2020

published in

1 reference

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27 March 2020

volume

47

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27 March 2020

issue

2

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27 March 2020

page(s)

314-326

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Recent advances in antigen processing and presentation

27 March 2020

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HLA-DM induces clip dissociation from MHC class II αβ dimers and facilitates peptide loading

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The impact of DM on MHC class II-restricted antigen presentation can be altered by manipulation of MHC-peptide kinetic stability

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HLA-DM targets the hydrogen bond between the histidine at position beta81 and peptide to dissociate HLA-DR-peptide complexes.

21 January 2018

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Enhanced catalytic action of HLA-DM on the exchange of peptides lacking backbone hydrogen bonds between their N-terminal region and the MHC class II alpha-chain.

21 January 2018

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21 January 2018

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Cutting edge: HLA-DM-mediated peptide exchange functions normally on MHC class II-peptide complexes that have been weakened by elimination of a conserved hydrogen bond

21 January 2018

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HLA-DM recognizes the flexible conformation of major histocompatibility complex class II.

21 January 2018

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HLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptide

21 January 2018

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Conformational lability in the class II MHC 310 helix and adjacent extended strand dictate HLA-DM susceptibility and peptide exchange

21 January 2018

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Crystal Structure of the HLA-DM–HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection

21 January 2018

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The Thermodynamic Mechanism of Peptide-MHC Class II Complex Formation Is a Determinant of Susceptibility to HLA-DM.

21 January 2018

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Susceptibility to HLA-DM Protein Is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with Peptide

21 January 2018

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HLA and autoimmune diseases: Type 1 diabetes (T1D) as an example

21 January 2018

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Human leukocyte antigen class II and type 1 diabetes in Latin America: a combined meta-analysis of association and family-based studies

21 January 2018

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HLA-Class II in Latin American patients with type 1 diabetes

21 January 2018

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The rare HLA-DQA1*03-DQB1*02 haplotype confers susceptibility to type 1 diabetes in whites and is preferentially associated with early clinical disease onset in male subjects

21 January 2018

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21 January 2018

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HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: analysis of the type 1 diabetes genetics consortium families

21 January 2018

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Genetics of type 1 diabetes mellitus

21 January 2018

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Type 1 diabetes-associated HLA-DQ8 transdimer accommodates a unique peptide repertoire

21 January 2018

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Structural and Functional Studies of trans -Encoded HLA-DQ2.3 (DQA1*03:01/DQB1*02:01) Protein Molecule

21 January 2018

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Type 1 diabetes associated HLA-DQ2 and DQ8 molecules are relatively resistant to HLA-DM mediated release of invariant chain-derived CLIP peptides

21 January 2018

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An insertion mutant in DQA1*0501 restores susceptibility to HLA-DM: implications for disease associations.

21 January 2018

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Complexes of two cohorts of CLIP peptides and HLA-DQ2 of the autoimmune DR3-DQ2 haplotype are poor substrates for HLA-DM

21 January 2018

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Large scale mass spectrometric profiling of peptides eluted from HLA molecules reveals N-terminal-extended peptide motifs

21 January 2018

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Utility of characteristic QTOF MS/MS fragmentation for MHC class I peptides.

21 January 2018

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Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Natural peptides selected by diabetogenic DQ8 and murine I-A(g7) molecules show common sequence specificity

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Allelic variation in key peptide-binding pockets discriminates between closely related diabetes-protective and diabetes-susceptible HLA-DQB1*06 alleles

21 January 2018

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21 January 2018

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Cutting edge: H-2DM is responsible for the large differences in presentation among peptides selected by I-Ak during antigen processing

21 January 2018

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7 January 2021

The kinetic stability of MHC class II:peptide complexes is a key parameter that dictates immunodominance

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7 January 2021

Transmembrane domain-mediated colocalization of HLA-DM and HLA-DR is required for optimal HLA-DM catalytic activity

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7 January 2021

Measurement of Peptide Binding to MHC Class II Molecules by Fluorescence Polarization

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7 January 2021

Identifiers

DOI

10.1002/EJI.201646656

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27861808%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

1 reference