(Q39226296)

English

Selective tyrosine kinase inhibition of insulin-like growth factor-1 receptor inhibits human and mouse breast cancer-induced bone cell activity, bone remodeling, and osteolysis

scientific article published on May 2013

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

Selective tyrosine kinase inhibition of insulin-like growth factor-1 receptor inhibits human and mouse breast cancer-induced bone cell activity, bone remodeling, and osteolysis (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

1 reference

ChEBI release 2020-05-28

1 reference

based on heuristic

inferred from title

Antonia Sophocleous

object named as

Antonia Sophocleous

2

0 references

object named as

John G Logan

1

0 references

object named as

Aymen I Idris

6

0 references

Valerie G Brunton

5

object named as

Valerie G Brunton

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

Morwenna T Muir

4

object named as

Morwenna Muir

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

author name string

Silvia Marino

3

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

publication date

1 May 2013

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

Journal of Bone and Mineral Research

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

28

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

1229-1242

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

Metastasis to bone: causes, consequences and therapeutic opportunities

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Pathogenesis of bone metastasis: a review

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Molecular mechanisms of osteolytic bone metastases

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Skeletal complications of breast cancer therapies

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Identification of common ligand binding determinants of the insulin and insulin-like growth factor 1 receptors. Insights into mechanisms of ligand binding

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

New concepts in regulation and function of the insulin-like growth factors: implications for understanding normal growth and neoplasia

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Growth hormone, insulin-like growth factors, and the skeleton

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

The insulin-like growth factor-I gene and osteoporosis: a critical appraisal

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

The role of the IGF system in cancer growth and metastasis: overview and recent insights

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

PI3K/Akt and MAPK/ERK1/2 signaling pathways are involved in IGF-1-induced VEGF-C upregulation in breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Elevated insulin-like growth factor 1 receptor signaling induces antiestrogen resistance through the MAPK/ERK and PI3K/Akt signaling routes

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Regulation of IGF-I receptor signaling in tumor cells.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

IGF-I secreted by osteoblasts acts as a potent chemotactic factor for osteoblasts.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Crosstalk between cancer cells and bone microenvironment in bone metastasis

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Genetic strategies for elucidating insulin-like growth factor action in bone

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Liver-derived IGF-I is permissive for ovariectomy-induced trabecular bone loss.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Role of IGF-I signaling in regulating osteoclastogenesis

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

The skeletal structure of insulin-like growth factor I-deficient mice

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Insulin-like growth factor-I and bone: lessons from mice and men.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

The insulin-like growth factor-I receptor as an oncogene

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Defining the pathway to insulin-like growth factor system targeting in cancer

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Insulin-like growth factor receptor (IGF-1R) in breast cancer subtypes.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

The GH1/IGF-1 axis polymorphisms and their impact on breast cancer development

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Resveratrol inhibits migration and invasion of human breast-cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Paracrine overexpression of insulin-like growth factor-1 enhances mammary tumorigenesis in vivo

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Inhibition of in vivo breast cancer growth by antisense oligodeoxynucleotides to type I insulin-like growth factor receptor mRNA involves inactivation of ErbBs, PI-3K/Akt and p42/p44 MAPK signaling pathways but not modulation of progesterone recepto

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Small interfering RNA targeted to IGF-IR delays tumor growth and induces proinflammatory cytokines in a mouse breast cancer model

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Treatment of murine breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor decreases the level of plasminogen activator transcripts, inhibits cell growth in vitro, and reduces tumorigenesis in vivo

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Disrupting insulin-like growth factor signaling as a potential cancer therapy

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

A novel, potent, and selective insulin-like growth factor-I receptor kinase inhibitor blocks insulin-like growth factor-I receptor signaling in vitro and inhibits insulin-like growth factor-I receptor dependent tumor growth in vivo

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Small-molecule inhibition and activation-loop trans-phosphorylation of the IGF1 receptor

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Assessment of the Alamar Blue assay for cellular growth and viability in vitro

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Dynamic monitoring of cell adhesion and spreading on microelectronic sensor arrays

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Discovery of OSI-906: a selective and orally efficacious dual inhibitor of the IGF-1 receptor and insulin receptor

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Osteoblasts are a major source of inflammatory cytokines in the tumor microenvironment of bone metastatic breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

RANKing intracellular signaling in osteoclasts

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Breast cancer cell line MDA-MB 231 exerts a potent and direct anti-apoptotic effect on mature osteoclasts

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1847

21 January 2018

Identifiers

10.1002/JBMR.1847

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

ResearchGate publication ID

0 references

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