(Q39226379)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23238993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

Autophagy induced by p53-reactivating molecules protects pancreatic cancer cells from apoptosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23238993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

0 references

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23238993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Massimo Donadelli

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23238993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

author name string

Claudia Fiorini

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23238993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Marta Menegazzi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23238993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Chiara Padroni

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23238993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Ilaria Dando

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23238993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Alex Gregorelli

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23238993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Chiara Costanzo

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23238993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Marta Palmieri

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23238993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

publication date

1 March 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23238993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23238993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23238993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

page(s)

337-346

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23238993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23238993%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s10495-012-0790-6

20 February 2020

exact match

0 references

cites work

Regulating the p53 pathway: in vitro hypotheses, in vivo veritas

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Live or let die: the cell's response to p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Genetic abnormalities in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Biogenesis of p53 involves cotranslational dimerization of monomers and posttranslational dimerization of dimers. Implications on the dominant negative effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Rescuing the function of mutant p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

21 January 2018

Drug discovery and p53.

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Modeling the therapeutic efficacy of p53 restoration in tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Restoration of p53 function leads to tumour regression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Pharmacological reactivation of mutant p53: from protein structure to the cancer patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

p53-Reactivating small molecules induce apoptosis and enhance chemotherapeutic cytotoxicity in head and neck squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Targeting wild-type and mutant p53 with small molecule CP-31398 blocks the growth of rhabdomyosarcoma by inducing reactive oxygen species-dependent apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Physiological functions of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Cell death pathology: cross-talk with autophagy and its clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

A ubiquitin-like system mediates protein lipidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

p53 regulation of the IGF-1/AKT/mTOR pathways and the endosomal compartment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Sestrin2 modulates AMPK subunit expression and its response to ionizing radiation in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

The genetics of the p53 pathway, apoptosis and cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Manipulation of the tumor suppressor p53 for potentiating cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Reactivation of mutant p53: molecular mechanisms and therapeutic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Restoration of p53 to limit tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Small molecules that reactivate mutant p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Rescue of the apoptotic-inducing function of mutant p53 by small molecule RITA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Reactivation of p53 by novel MDM2 inhibitors: implications for pancreatic cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

A dual role of p53 in the control of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Regulation of autophagy by cytoplasmic p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

p53 inhibits autophagy by interacting with the human ortholog of yeast Atg17, RB1CC1/FIP200.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Pancreatic cancers require autophagy for tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6

Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0790-6