(Q39298748)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22887478%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Embelin inhibits growth and induces apoptosis through the suppression of Akt/mTOR/S6K1 signaling cascades (English)

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11 February 2020

4

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11 February 2020

Gautam Sethi

11

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11 February 2020

author name string

Seong Won Kim

1

1 reference

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11 February 2020

Sung-Moo Kim

2

1 reference

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11 February 2020

Hang Bae

3

1 reference

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11 February 2020

Jun-Hee Lee

5

1 reference

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11 February 2020

Seok-Geun Lee

6

1 reference

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11 February 2020

Bum Sang Shim

7

1 reference

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11 February 2020

Sung-Hoon Kim

8

1 reference

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11 February 2020

Kyoo Seok Ahn

9

1 reference

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11 February 2020

Seung-Hoon Choi

10

1 reference

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11 February 2020

Kwang Seok Ahn

12

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11 February 2020

publication date

9 August 2012

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11 February 2020

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11 February 2020

volume

73

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11 February 2020

issue

3

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11 February 2020

page(s)

296-305

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[3H]-thymidine uptake and lipid peroxidation by tumor cells on embelin treatment: an in vitro study

11 February 2020

cites work

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Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database

21 January 2018

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Embelin, an inhibitor of X chromosome-linked inhibitor-of-apoptosis protein, blocks nuclear factor-kappaB (NF-kappaB) signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products

21 January 2018

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Cell-penetrating peptide-conjugated XIAP-inhibitory cyclic hexapeptides enter into Jurkat cells and inhibit cell proliferation

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Effect of the XIAP inhibitor Embelin on TRAIL-induced apoptosis of pancreatic cancer cells.

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Cell death in pancreatitis: caspases protect from necrotizing pancreatitis

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Trastuzumab signaling in ErbB2-overexpressing inflammatory breast cancer correlates with X-linked inhibitor of apoptosis protein expression

21 January 2018

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Peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of Embelin on colon carcinogenesis.

21 January 2018

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Embelin suppresses STAT3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase PTEN.

21 January 2018

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Embelin derivatives and their anticancer activity through microtubule disassembly

21 January 2018

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Role of PI3K/AKT/mTOR signaling in the cell cycle progression of human prostate cancer

21 January 2018

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The Akt-mTOR tango and its relevance to cancer

21 January 2018

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Biomarkers and patient selection for PI3K/Akt/mTOR targeted therapies: current status and future directions

21 January 2018

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Deciphering the role of PI3K/Akt/mTOR pathway in breast cancer biology and pathogenesis

21 January 2018

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

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Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Detecting activation of ribosomal protein S6 kinase by complementary DNA and tissue microarray analysis

21 January 2018

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Overexpression of P70 S6 kinase protein is associated with increased risk of locoregional recurrence in node-negative premenopausal early breast cancer patients

21 January 2018

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β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activation

21 January 2018

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Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteins

21 January 2018

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21 January 2018

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21 January 2018

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Risk factors for prostate cancer: An hospital-based case-control study from Mumbai, India

21 January 2018

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Position of the American Dietetic Association and Dietitians of Canada: Vegetarian diets

21 January 2018

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21 January 2018

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Micellar delivery of bicalutamide and embelin for treating prostate cancer

21 January 2018

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Prognostic significance of XIAP expression in DLBCL and effect of its inhibition on AKT signalling.

21 January 2018

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Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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