(Q39331696)

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Increased acetylation of lysine 317/320 of p53 caused by BCR-ABL protects from cytoplasmic translocation of p53 and mitochondria-dependent apoptosis in response to DNA damage

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Europe PubMed Central

11 September 2017

Increased acetylation of lysine 317/320 of p53 caused by BCR-ABL protects from cytoplasmic translocation of p53 and mitochondria-dependent apoptosis in response to DNA damage (English)

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Europe PubMed Central

11 September 2017

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Paulina Podszywalow-Bartnicka

3

object named as

Paulina Podszywalow-Bartnicka

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Monika Kusio-Kobialka

1

object named as

Monika Kusio-Kobialka

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Europe PubMed Central

11 September 2017

Krzysztof Skowronek

object named as

Krzysztof Skowronek

5

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Sharon L McKenna

object named as

Sharon L McKenna

6

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Katarzyna Piwocka

object named as

Katarzyna Piwocka

9

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object named as

Frank J Dekker

8

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object named as

Ewa Sikora

4

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author name string

Kamila Wolanin

2

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Europe PubMed Central

11 September 2017

Massimo Ghizzoni

7

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Europe PubMed Central

11 September 2017

publication date

1 September 2012

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Europe PubMed Central

11 September 2017

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Europe PubMed Central

11 September 2017

17

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Europe PubMed Central

11 September 2017

9

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Europe PubMed Central

11 September 2017

950-963

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Europe PubMed Central

11 September 2017

https://scigraph.springernature.com/pub.10.1007/s10495-012-0739-9

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An oncogene-induced DNA damage model for cancer development

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Genome maintenance mechanisms are critical for preventing cancer as well as other aging-associated diseases

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Genomic instability in cancer development

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Chronic myeloid leukaemia as a model of disease evolution in human cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Molecular abnormalities in chronic myeloid leukemia: deregulation of cell growth and apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Control of apoptosis by p53.

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Targeting p53 to mitochondria for cancer therapy

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

p53-dependent repression of the human MCL-1 gene encoding an anti-apoptotic member of the BCL-2 family: the role of Sp1 and of basic transcription factor binding sites in the MCL-1 promoter

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Transcription-independent p53 apoptosis: an alternative route to death

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Regulating the p53 pathway: in vitro hypotheses, in vivo veritas

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Tickets for p53 journey among organelles.

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

p53 acetylation is crucial for its transcription-independent proapoptotic functions

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

The transcriptional coactivators p300 and CBP are histone acetyltransferases

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

DNA damage activates p53 through a phosphorylation-acetylation cascade

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

BCR/ABL, DNA damage and DNA repair: implications for new treatment concepts

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

BCR/ABL inhibits mismatch repair to protect from apoptosis and induce point mutations

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

High Bcr-Abl expression prevents the translocation of Bax and Bad to the mitochondrion

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Improved inhibition of the histone acetyltransferase PCAF by an anacardic acid derivative

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Transcription-independent pro-apoptotic functions of p53.

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

BclxL changes conformation upon binding to wild-type but not mutant p53 DNA binding domain

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Regulation of p53 localization

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Inhibition of the PCAF histone acetyl transferase and cell proliferation by isothiazolones.

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Cytoplasmic functions of the tumour suppressor p53.

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Transcription, apoptosis and p53: catch-22.

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Dissection of transcriptional and non-transcriptional p53 activities in the response to genotoxic stress

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

BH3-triggered structural reorganization drives the activation of proapoptotic BAX.

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Two genetic hits (more or less) to cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Triggering of apoptosis by Puma is determined by the threshold set by prosurvival Bcl-2 family proteins

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

BAX and BAK mediate p53-independent suppression of tumorigenesis

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Acetylation of mouse p53 at lysine 317 negatively regulates p53 apoptotic activities after DNA damage

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate.

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

p53 has a direct apoptogenic role at the mitochondria

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Acetylation of p53 inhibits its ubiquitination by Mdm2.

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation.

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Monoubiquitylation promotes mitochondrial p53 translocation

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Mitochondrially targeted wild-type p53 suppresses growth of mutant p53 lymphomas in vivo.

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

PUMA couples the nuclear and cytoplasmic proapoptotic function of p53

1 reference

https://api.crossref.org/works/10.1007%2FS10495-012-0739-9

21 January 2018

Identifiers

10.1007/S10495-012-0739-9

1 reference

Europe PubMed Central

11 September 2017

1 reference

Europe PubMed Central

11 September 2017

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