(Q39398074)

11 September 2017

title

Metabolic signatures of GS-CHO cell clones associated with butyrate treatment and culture phase transition (English)

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11 September 2017

4

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11 September 2017

Laura C Barreiro

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Nuno Carinhas

object named as

Nuno Carinhas

1

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Ana P. Teixeira

object named as

Ana P Teixeira

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Paula Marques Alves

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Paula M Alves

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author name string

Tiago M Duarte

2

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11 September 2017

publication date

7 July 2013

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Biotechnology and Bioengineering

11 September 2017

published in

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11 September 2017

volume

110

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11 September 2017

issue

12

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11 September 2017

page(s)

3244-3257

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Metabolic flux analysis of CHO cells at growth and non-growth phases using isotopic tracers and mass spectrometry

11 September 2017

cites work

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Parallel labeling experiments with [1,2-(13)C]glucose and [U-(13)C]glutamine provide new insights into CHO cell metabolism

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Sodium butyrate stimulates monoclonal antibody over-expression in CHO cells by improving gene accessibility

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A single nutrient feed supports both chemically defined NS0 and CHO fed-batch processes: Improved productivity and lactate metabolism

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Flux balance analysis of CHO cells before and after a metabolic switch from lactate production to consumption

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Na-butyrate sustains energetic states of metabolism and t-PA productivity of CHO cells.

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On metabolic shift to lactate consumption in fed-batch culture of mammalian cells

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Evidence for intracellular partitioning of serine and glycine metabolism in Chinese hamster ovary cells

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21 January 2018

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Modeling hybridoma cell metabolism using a generic genome-scale metabolic model of Mus musculus

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Peak antibody production is associated with increased oxidative metabolism in an industrially relevant fed-batch CHO cell culture.

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Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux

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Decreasing lactate level and increasing antibody production in Chinese Hamster Ovary cells (CHO) by reducing the expression of lactate dehydrogenase and pyruvate dehydrogenase kinases

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/BIT.24983

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11 September 2017

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