(Q39464436)

12 September 2017

title

Survival of pancreatic beta cells is partly controlled by a TCF7L2-p53-p53INP1-dependent pathway (English)

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12 September 2017

11

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12 September 2017

Enming Zhang

2

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Leif Groop

9

object named as

Leif Groop

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12 September 2017

Yuedan Zhou

1

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12 September 2017

Christine Berggreen

3

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12 September 2017

Xingjun Jing

4

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12 September 2017

Peter Osmark

5

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12 September 2017

Stefan Lang

6

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12 September 2017

Corrado M Cilio

7

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12 September 2017

Olga Göransson

8

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12 September 2017

Erik Renström

10

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12 September 2017

publication date

30 September 2011

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12 September 2017

published in

Human Molecular Genetics

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12 September 2017

volume

21

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12 September 2017

issue

1

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12 September 2017

page(s)

196-207

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Clinical risk factors, DNA variants, and the development of type 2 diabetes

12 September 2017

cites work

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Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

21 January 2018

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The new type 2 diabetes gene TCF7L2

21 January 2018

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Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

21 January 2018

1 reference

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RETRACTED: Transcription factor 7-like 2 regulates beta-cell survival and function in human pancreatic islets

21 January 2018

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Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas

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Identification of c-MYC as a target of the APC pathway

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

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Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells

21 January 2018

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Disease-associated loci are significantly over-represented among genes bound by transcription factor 7-like 2 (TCF7L2) in vivo

21 January 2018

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Unique splicing pattern of the TCF7L2 gene in human pancreatic islets.

21 January 2018

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Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/beta-catenin targets

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Tissue-specific alternative splicing of TCF7L2.

21 January 2018

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TileMap: create chromosomal map of tiling array hybridizations

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Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

21 January 2018

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Akt and PTEN: beta-cell mass and pancreas plasticity.

21 January 2018

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p53DINP1, a p53-inducible gene, regulates p53-dependent apoptosis

21 January 2018

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p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

21 January 2018

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Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis

21 January 2018

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The ADAM metalloproteinases

21 January 2018

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TP53INP1s and homeodomain-interacting protein kinase-2 (HIPK2) are partners in regulating p53 activity.

21 January 2018

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Molecular and functional characterization of the stress-induced protein (SIP) gene and its two transcripts generated by alternative splicing. SIP induced by stress and promotes cell death

21 January 2018

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Molecular function of TCF7L2: Consequences of TCF7L2 splicing for molecular function and risk for type 2 diabetes

21 January 2018

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TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action.

21 January 2018

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TCF7L2 controls insulin gene expression and insulin secretion in mature pancreatic beta-cells

21 January 2018

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TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells

21 January 2018

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TCF7L2 splice variants have distinct effects on beta-cell turnover and function

21 January 2018

1 reference

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The WNT signalling pathway and diabetes mellitus

21 January 2018

1 reference

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The Wnt signaling pathway effector TCF7L2 and type 2 diabetes mellitus

21 January 2018

1 reference

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Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation

21 January 2018

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Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors

21 January 2018

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Apoptotic, regenerative, and immune-related signaling in human islets from type 2 diabetes individuals.

21 January 2018

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p53 and E2f: partners in life and death

21 January 2018

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Phosphorylation of TCF proteins by homeodomain-interacting protein kinase 2.

21 January 2018

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Identification of Tcf-4 as a transcriptional target of p53 signalling

21 January 2018

1 reference

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Activation of p53-dependent apoptosis by acute ablation of glycogen synthase kinase-3beta in colorectal cancer cells

21 January 2018

1 reference

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A map of open chromatin in human pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR454

Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR454

Identification of T-cell factor-4 isoforms that contribute to the malignant phenotype of hepatocellular carcinoma cells

21 January 2018

1 reference

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An algorithm for finding protein-DNA binding sites with applications to chromatin-immunoprecipitation microarray experiments

21 January 2018

1 reference

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Wnt breakers in colon cancer

21 January 2018

1 reference

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HNF1B and JAZF1 genes, diabetes, and prostate cancer risk

21 January 2018

1 reference

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Two variants on chromosome 17 confer prostate cancer risk and the one in TCF2 protects against type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR454

Transcription factor 7-like 2 polymorphism and colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR454

Diabetes genes and prostate cancer in the Atherosclerosis Risk in Communities study

21 January 2018

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1093/HMG/DDR454

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12 September 2017

1 reference