(Q39509450)

12 September 2017

The proto-oncogene Pim-1 is a target of miR-33a (English)

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12 September 2017

7

R K Hartmann

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12 September 2017

M Thomas

1

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12 September 2017

K Lange-Grünweller

2

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12 September 2017

U Weirauch

3

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12 September 2017

D Gutsch

4

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12 September 2017

A Aigner

5

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12 September 2017

A Grünweller

6

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12 September 2017

language of work or name

English

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publication date

11 July 2011

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12 September 2017

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12 September 2017

31

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12 September 2017

7

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12 September 2017

918-928

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https://scigraph.springernature.com/pub.10.1038/onc.2011.278

12 September 2017

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cites work

Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

The survival kinases Akt and Pim as potential pharmacological targets

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

miR-15a and miR-16-1 in cancer: discovery, function and future perspectives

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

The oncogenic serine/threonine kinase Pim-1 phosphorylates and inhibits the activity of Cdc25C-associated kinase 1 (C-TAK1): a novel role for Pim-1 at the G2/M cell cycle checkpoint

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

The serine/threonine kinase Pim-1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

MicroRNAs: genomics, biogenesis, mechanism, and function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

MicroRNAs: target recognition and regulatory functions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Principles of microRNA-target recognition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Real-time quantification of microRNAs by stem-loop RT-PCR

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Pim family kinases enhance tumor growth of prostate cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

miR-15 and miR-16 induce apoptosis by targeting BCL2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Causes and consequences of microRNA dysregulation in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Targeting the AKT protein kinase for cancer chemoprevention

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Oncomirs - microRNAs with a role in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

MicroRNAs: key regulators of stem cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

MicroRNA targeting specificity in mammals: determinants beyond seed pairing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Comparison of different antisense strategies in mammalian cells using locked nucleic acids, 2'-O-methyl RNA, phosphorothioates and small interfering RNA.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

A complex interplay between Akt, TSC2 and the two mTOR complexes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

MicroRNA replacement therapy for miR-145 and miR-33a is efficacious in a model of colon carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

MicroRNA gene expression deregulation in human breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

RAS is regulated by the let-7 microRNA family

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin module for acute myelogenous leukemia therapy: from bench to bedside

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Identification of G1 kinase activity for cdk6, a novel cyclin D partner

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Physical and functional interactions between Pim-1 kinase and Cdc25A phosphatase. Implications for the Pim-1-mediated activation of the c-Myc signaling pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Pim-1 regulates cardiomyocyte survival downstream of Akt.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

For better or for worse: the role of Pim oncogenes in tumorigenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

c-Myc-regulated microRNAs modulate E2F1 expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Structural basis of constitutive activity and a unique nucleotide binding mode of human Pim-1 kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

MiR-33 contributes to the regulation of cholesterol homeostasis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Widespread changes in protein synthesis induced by microRNAs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Regression of murine lung tumors by the let-7 microRNA

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Predisposition to lymphomagenesis in pim-1 transgenic mice: cooperation with c-myc and N-myc in murine leukemia virus-induced tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Expression of the miR-17-92 polycistron in chronic myeloid leukemia (CML) CD34+ cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Mice bearing the E mu-myc and E mu-pim-1 transgenes develop pre-B-cell leukemia prenatally

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Structural insights into RNA processing by the human RISC-loading complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

The 44 kDa Pim-1 kinase directly interacts with tyrosine kinase Etk/BMX and protects human prostate cancer cells from apoptosis induced by chemotherapeutic drugs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Physiological functions of protein kinase B/Akt

31 March 2020

2 references

https://api.crossref.org/works/10.1038%2FONC.2011.278

31 March 2020

https://api.crossref.org/works/10.1038%2FONC.2011.278

inferred from DOI database lookup

7 January 2021

based on heuristic

Impact of hepatitis B virus infection on outcome following resection for intrahepatic cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Pim kinase-dependent inhibition of c-Myc degradation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

Pim-1 kinase-dependent phosphorylation of p21Cip1/WAF1 regulates its stability and cellular localization in H1299 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

PIM1-dependent phosphorylation of histone H3 at serine 10 is required for MYC-dependent transcriptional activation and oncogenic transformation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.278

31 March 2020

Identifiers

DOI

10.1038/ONC.2011.278

1 reference

12 September 2017

1 reference