(Q39588237)

13 September 2017

Inhibition of TGF-β signaling, vasculogenic mimicry and proinflammatory gene expression by isoxanthohumol (English)

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13 September 2017

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3

Timm Anke

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13 September 2017

Annegret Serwe

1

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13 September 2017

Kristina Rudolph

series ordinal

2

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13 September 2017

Gerhard Erkel

series ordinal

4

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13 September 2017

language of work or name

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22 February 2011

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Investigational New Drugs

13 September 2017

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13 September 2017

30

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13 September 2017

3

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13 September 2017

898-915

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https://scigraph.springernature.com/pub.10.1007/s10637-011-9643-3

13 September 2017

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cites work

Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Transforming growth factor-beta regulation of immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Smad transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Role of transforming growth factor-beta superfamily signaling pathways in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Specificity and versatility in tgf-beta signaling through Smads

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Non-Smad TGF-beta signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Transforming growth factor-beta signaling in cancer invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Transforming growth factor-beta signal transduction in angiogenesis and vascular disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

TGF-beta: a mobile purveyor of immune privilege

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Development of TGF-beta signalling inhibitors for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Targeting TGFbeta signaling for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Antiangiogenic effects of flavonoids and chalcones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Beer constituents as potential cancer chemopreventive agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Quantitative analysis of xanthohumol and related prenylflavonoids in hops and beer by liquid chromatography-tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Oxacyclododecindione, a novel inhibitor of IL-4 signaling from Exserohilum rostratum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Requirements for interleukin-4-induced gene expression and functional characterization of Stat6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Human airway epithelial cells produce IP-10 (CXCL10) in vitro and in vivo upon rhinovirus infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Angiotensinogen gene expression is dependent on signal transducer and activator of transcription 3-mediated p300/cAMP response element binding protein-binding protein coactivator recruitment and histone acetyltransferase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

A new mathematical model for relative quantification in real-time RT-PCR

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Hypoxia: a key regulator of angiogenesis in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Targeting hypoxia cell signaling for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Small molecule inhibitors of Stat3 signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Signal transducers and activators of transcription (STATs): Novel targets of chemopreventive and chemotherapeutic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

The DNA binding activities of Smad2 and Smad3 are regulated by coactivator-mediated acetylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Signaling mechanisms, interaction partners, and target genes of STAT6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Cancer-related inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Targeting innate immunity protein kinase signalling in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Transforming growth factor-beta and the immune response: implications for anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Smad3 and Smad4 mediate transcriptional activation of the human Smad7 promoter by transforming growth factor beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-beta: implications for carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Vasculogenic mimicry: current status and future prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Tracking STAT nuclear traffic

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Serine phosphorylation of STATs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Acetylation by histone acetyltransferase CREB-binding protein/p300 of STAT6 is required for transcriptional activation of the 15-lipoxygenase-1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

The STATs of cancer--new molecular targets come of age

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

STAT3 as a central regulator of tumor metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

STAT3: a critical transcription activator in angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Signal transducers and activators of transcription as targets for small organic molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

A cytokine-mediated link between innate immunity, inflammation, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Inflammation and cancer: how hot is the link?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB (p65) by xanthohumol leads to suppression of NF-kappaB-regulated gene products and potentiation of apoptosis in leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Antiinvasive effect of xanthohumol, a prenylated chalcone present in hops (Humulus lupulus L.) and beer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Xanthohumol inhibits inflammatory factor production and angiogenesis in breast cancer xenografts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Differential anti-inflammatory pathway by xanthohumol in IFN-gamma and LPS-activated macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Inhibition of endothelial cell functions by novel potential cancer chemopreventive agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

AMPLIFICATION AND DIRECT SEQUENCING OF FUNGAL RIBOSOMAL RNA GENES FOR PHYLOGENETICS

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9643-3

Genomics reveals traces of fungal phenylpropanoid-flavonoid metabolic pathway in the f ilamentous fungus Aspergillus oryzae

21 January 2018

1 reference

12 December 2020

TGF-beta in cancer and as a therapeutic target

1 reference

12 December 2020

Mechanisms of the antiangiogenic activity by the hop flavonoid xanthohumol: NF-kappaB and Akt as targets

1 reference

12 December 2020

Actions of TGF-beta as tumor suppressor and pro-metastatic factor in human cancer.

1 reference

12 December 2020

Cancer chemopreventive activity of Xanthohumol, a natural product derived from hop.

1 reference

12 December 2020

Inhibition of inducible TNF-alpha expression by oxaspirodion, a novel spiro-compound from the ascomycete Chaetomium subspirale

1 reference

12 December 2020

Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors.

1 reference

12 December 2020

Signalling pathways in vasculogenic mimicry

1 reference

12 December 2020

Inhibition of interleukin-6 signaling by galiellalactone

1 reference

12 December 2020

A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-kappa B.

1 reference

12 December 2020

Smad3 is acetylated by p300/CBP to regulate its transactivation activity

1 reference

12 December 2020

10.1007/S10637-011-9643-3

Identifiers

DOI

1 reference

13 September 2017

1 reference