(Q39639296)

English

Hydrophile scanning as a complement to alanine scanning for exploring and manipulating protein-protein recognition: application to the Bim BH3 domain

scientific article published on 8 May 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Hydrophile scanning as a complement to alanine scanning for exploring and manipulating protein-protein recognition: application to the Bim BH3 domain (English)

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

1 reference

based on heuristic

inferred from title

author name string

Melissa D Boersma

1

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Jack D Sadowsky

2

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

York A Tomita

3

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Samuel H Gellman

4

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

publication date

8 May 2008

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Protein Science

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

17

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

7

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

1232-1240

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Crystal structure of ABT-737 complexed with Bcl-xL: implications for selectivity of antagonists of the Bcl-2 family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442000

14 September 2017

Structural insights into the degradation of Mcl-1 induced by BH3 domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442000

14 September 2017

Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein

1 reference

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The Bcl-2 apoptotic switch in cancer development and therapy

1 reference

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14 September 2017

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

1 reference

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14 September 2017

Studies leading to potent, dual inhibitors of Bcl-2 and Bcl-xL

1 reference

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Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

1 reference

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Mutagenesis-based definitions and probes of residue burial in proteins.

1 reference

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14 September 2017

Enhanced metabolic stability and protein-binding properties of artificial alpha helices derived from a hydrogen-bond surrogate: application to Bcl-xL.

1 reference

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14 September 2017

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

1 reference

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A general framework for development and data analysis of competitive high-throughput screens for small-molecule inhibitors of protein-protein interactions by fluorescence polarization

1 reference

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14 September 2017

Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442000

14 September 2017

Structural biology of the Bcl-2 family of proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442000

14 September 2017

The structure of a Bcl-xL/Bim fragment complex: implications for Bim function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442000

14 September 2017

The role of the Bcl-2 protein family in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442000

14 September 2017

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442000

14 September 2017

Combinatorial alanine-scanning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442000

14 September 2017

Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442000

14 September 2017

BH3-Only proteins-essential initiators of apoptotic cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442000

14 September 2017

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442000

14 September 2017

A hot spot of binding energy in a hormone-receptor interface

1 reference

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Ionization behavior of the cleft carboxyls in lysozyme-substrate complexes

1 reference

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14 September 2017

Calculation of protein extinction coefficients from amino acid sequence data

1 reference

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14 September 2017

Protein engineering and the study of structure--function relationships in receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442000

14 September 2017

New apoptosis drugs face critical test

1 reference

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14 September 2017

Sequence and helicity requirements for the proapoptotic activity of Bax BH3 peptides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442000

14 September 2017

Modeling backbone flexibility to achieve sequence diversity: the design of novel alpha-helical ligands for Bcl-xL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442000

25 September 2017

High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis

1 reference

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15 June 2018

Inverse electrostatic effect: electrostatic repulsion in the unfolded state stabilizes a leucine zipper

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442000

21 August 2018

Inter-helical interactions in the leucine zipper coiled coil dimer: pH and salt dependence of coupling energy between charged amino acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442000

21 August 2018

Upgrading the BCL-2 network

1 reference

https://pubmed.ncbi.nlm.nih.gov/18467496

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(alpha/beta+alpha)-peptide antagonists of BH3 domain/Bcl-x(L) recognition: toward general strategies for foldamer-based inhibition of protein-protein interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/18467496

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of interhelical electrostatic interactions in the GCN4 leucine zipper

1 reference

https://pubmed.ncbi.nlm.nih.gov/18467496

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1110/PS.032896.107

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

ResearchGate publication ID

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