(Q39851605)

15 September 2017

title

Biochemical properties of mammalian TREX1 and its association with DNA replication and inherited inflammatory disease (English)

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15 September 2017

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1

Tomas Lindahl

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15 September 2017

Deborah E Barnes

2

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15 September 2017

Yun-Gui Yang

series ordinal

3

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15 September 2017

Peter Robins

series ordinal

4

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15 September 2017

publication date

1 June 2009

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Biochemical Society Transactions

15 September 2017

published in

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15 September 2017

volume

37

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15 September 2017

issue

Pt 3

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15 September 2017

page(s)

535-538

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A human DNA editing enzyme homologous to the Escherichia coli DnaQ/MutD protein

15 September 2017

cites work

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/citations/10.1093/EMBOJ/18.13.3868

Excision of 3' termini by the Trex1 and TREX2 3'-->5' exonucleases. Characterization of the recombinant proteins

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

Stabilization of perfect and imperfect tandem repeats by single-strand DNA exonucleases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

Exonuclease X of Escherichia coli. A novel 3'-5' DNase and Dnaq superfamily member involved in DNA repair.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

New roles for the major human 3'-5' exonuclease TREX1 in human disease

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

Structure of the dimeric exonuclease TREX1 in complex with DNA displays a proline-rich binding site for WW Domains

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

C-terminal truncations in human 3'-5' DNA exonuclease TREX1 cause autosomal dominant retinal vasculopathy with cerebral leukodystrophy

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

Gene-targeted mice lacking the Trex1 (DNase III) 3'-->5' DNA exonuclease develop inflammatory myocarditis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

TREX1 DNA exonuclease deficiency, accumulation of single stranded DNA and complex human genetic disorders

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

The TREX1 double-stranded DNA degradation activity is defective in dominant mutations associated with autoimmune disease.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

The crystal structure of TREX1 explains the 3' nucleotide specificity and reveals a polyproline II helix for protein partnering

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

Nucleic acid-mediated inflammatory diseases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

Trex1 prevents cell-intrinsic initiation of autoimmunity

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

Reaction mechanism of the epsilon subunit of E. coli DNA polymerase III: insights into active site metal coordination and catalytically significant residues.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

Structure and expression of the TREX1 and TREX2 3' --> 5' exonuclease genes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

Clinical and molecular phenotype of Aicardi-Goutieres syndrome

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BST0370535

Identifiers

DOI

10.1042/BST0370535

1 reference

15 September 2017

1 reference