(Q40074467)

17 September 2017

title

Novel (n)PKC kinases phosphorylate Nef for increased HIV transcription, replication and perinuclear targeting (English)

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17 September 2017

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Oliver T Fackler

9

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Andreas S Baur

10

object named as

Andreas S Baur

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17 September 2017

Dietlinde Wolf

1

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17 September 2017

Simone I Giese

2

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17 September 2017

Vanessa Witte

3

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17 September 2017

Ellen Krautkrämer

4

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17 September 2017

Susanna Trapp

5

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17 September 2017

Gabriele Sass

6

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17 September 2017

Claudia Haller

7

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17 September 2017

Katja Blume

8

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17 September 2017

language of work or name

English

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publication date

29 September 2007

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17 September 2017

number of pages

10

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based on heuristic

inferred from page(s)

published in

Virology

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17 September 2017

volume

370

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17 September 2017

issue

1

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17 September 2017

page(s)

45-54

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Dynamic Nef and Nef dynamics: how structure could explain the complex activities of this small HIV protein

17 September 2017

cites work

1 reference

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The N-Terminus of Nef from HIV-1/SIV Associates with a Protein Complex Containing Lck and a Serine Kinase

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A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor

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Protein Kinase C-mediated Phosphorylation of HIV-I Nef in Human Cell Lines

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Downregulation of protein kinase C-gamma is independent of a functional kinase domain

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Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machinery

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The HIV-1 pathogenicity factor Nef interferes with maturation of stimulatory T-lymphocyte contacts by modulation of N-Wasp activity

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HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis

7 January 2021

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Human immunodeficiency virus type 1 Nef activates p21-activated kinase via recruitment into lipid rafts

7 January 2021

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Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules

7 January 2021

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7 January 2021

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Protein kinase C group B members PKC-delta, -epsilon, -zeta and PKC-L(eta). Comparison of properties of recombinant proteins in vitro and in vivo

7 January 2021

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7 January 2021

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7 January 2021

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Negative factor from SIV binds to the catalytic subunit of the V-ATPase to internalize CD4 and to increase viral infectivity

7 January 2021

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7 January 2021

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The Nef protein of human immunodeficiency virus establishes superinfection immunity by a dual strategy to downregulate cell-surface CCR5 and CD4.

7 January 2021

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The Nef protein of human immunodeficiency virus is a broad-spectrum modulator of chemokine receptor cell surface levels that acts independently of classical motifs for receptor endocytosis and Galphai signaling

7 January 2021

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The HIV-1 nef gene acts as a positive viral infectivity factor

7 January 2021

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pEF-BOS, a powerful mammalian expression vector

7 January 2021

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Nef associates with p21-activated kinase 2 in a p21-GTPase-dependent dynamic activation complex within lipid rafts.

7 January 2021

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7 January 2021

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Cdc42/Rac1-mediated activation primes PAK2 for superactivation by tyrosine phosphorylation

7 January 2021

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7 January 2021

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Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4

7 January 2021

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Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

7 January 2021

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Photolabeling of Prostaglandin Endoperoxide H Synthase-1 with 3-Trifluoro-3-(m-Iiodophenyl)diazirine as a Probe of Membrane Association and the Cyclooxygenase Active Site

7 January 2021

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The effects of HIV-1 Nef on CD4 surface expression and viral infectivity in lymphoid cells are independent of rafts

7 January 2021

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7 January 2021

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Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinase

7 January 2021

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Human immunodeficiency virus type-1 infection impairs the formation of the immunological synapse

7 January 2021

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The Nef protein of HIV-1 associates with rafts and primes T cells for activation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.015

HIV-1 Nef association with cellular serine kinase correlates with enhanced virion infectivity and efficient proviral DNA synthesis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.015

HIV-1 Nef mimics an integrin receptor signal that recruits the polycomb group protein Eed to the plasma membrane

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.015

HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.015

Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.015

Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.015

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.VIROL.2007.08.015

1 reference

17 September 2017

1 reference