(Q40134426)

English

The farnesyltransferase inhibitor lonafarnib induces CCAAT/enhancer-binding protein homologous protein-dependent expression of death receptor 5, leading to induction of apoptosis in human cancer cells.

scientific article published on 9 May 2007

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17493934%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

The farnesyltransferase inhibitor lonafarnib induces CCAAT/enhancer-binding protein homologous protein-dependent expression of death receptor 5, leading to induction of apoptosis in human cancer cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17493934%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17493934%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

6

object named as

Fadlo R Khuri

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17493934%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

author name string

Shi-Yong Sun

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17493934%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Wei Zou

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17493934%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Ping Yue

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17493934%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Adam I Marcus

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17493934%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

language of work or name

0 references

publication date

9 May 2007

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17493934%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17493934%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

282

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17493934%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

26

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17493934%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

18800-18809

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17493934%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Protein farnesylation: implications for normal physiology, malignant transformation, and cancer therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Farnesyl transferase inhibitor SCH66336 is cytostatic, pro-apoptotic and enhances chemosensitivity to cisplatin in melanoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Overcoming STI571 resistance with the farnesyl transferase inhibitor SCH66336.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Treatment of Bcr/Abl-positive acute lymphoblastic leukemia in P190 transgenic mice with the farnesyl transferase inhibitor SCH66336.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Phase I study of the farnesyltransferase inhibitor lonafarnib with paclitaxel in solid tumors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Phase II study of the farnesyltransferase inhibitor lonafarnib with paclitaxel in patients with taxane-refractory/resistant nonsmall cell lung carcinoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Farnesyltransferase inhibitors reverse taxane resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Apoptotic pathways: paper wraps stone blunts scissors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Death receptors: signaling and modulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

TRAIL and apoptosis induction by TNF-family death receptors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Death receptors in chemotherapy and cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Roles of CHOP/GADD153 in endoplasmic reticulum stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Proteasome inhibitor MG132 induces death receptor 5 through CCAAT/enhancer-binding protein homologous protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

3,3'-diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Non-Ras targets of farnesyltransferase inhibitors: focus on Rho.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Cdk inhibitors, roscovitine and olomoucine, synergize with farnesyltransferase inhibitor (FTI) to induce efficient apoptosis of human cancer cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Farnesyltransferase inhibitor BMS-214662 induces apoptosis in B-cell chronic lymphocytic leukemia cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

The farnesyltransferase inhibitor Lonafarnib induces growth arrest or apoptosis of human lung cancer cells without downregulation of Akt.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Mechanisms of apoptosis induced by the synthetic retinoid CD437 in human non-small cell lung carcinoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Nuclear retinoic acid receptors: cloning, analysis, and function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Proteolytic cleavage of ras GTPase-activating protein during apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Phase I and pharmacological study of the oral farnesyltransferase inhibitor SCH 66336 given once daily to patients with advanced solid tumours

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

A phase II trial of farnesyl protein transferase inhibitor SCH 66336, given by twice-daily oral administration, in patients with metastatic colorectal cancer refractory to 5-fluorouracil and irinotecan

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Role of p53 mutations, protein function and DNA damage for the radiosensitivity of human tumour cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

p53-independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-gamma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Farnesyl transferase inhibitors enhance death receptor signals and induce apoptosis in multiple myeloma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611438200

21 January 2018

Identifiers

10.1074/JBC.M611438200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17493934%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17493934%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q40134426&oldid=1533766938"