(Q40149893)

17 September 2017

title

Novel targets for antibiotics in Staphylococcus aureus (English)

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17 September 2017

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Staphylococcus aureus

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Knut Ohlsen

1

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17 September 2017

Udo Lorenz

series ordinal

2

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17 September 2017

publication date

1 December 2007

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17 September 2017

number of pages

12

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based on heuristic

inferred from page(s)

published in

Future Microbiology

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17 September 2017

volume

2

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17 September 2017

issue

6

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17 September 2017

page(s)

655-666

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National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004.

17 September 2017

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Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA.

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The essential Staphylococcus aureus gene fmhB is involved in the first step of peptidoglycan pentaglycine interpeptide formation

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Robust Salmonella metabolism limits possibilities for new antimicrobials.

21 January 2018

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Discovery of a small molecule that inhibits cell division by blocking FtsZ, a novel therapeutic target of antibiotics

21 January 2018

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Targeting cell division: small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality

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The evolution of peptide deformylase as a target: contribution of biochemistry, genetics and genomics

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Therapeutic potential of peptide deformylase inhibitors

21 January 2018

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Crystal structure of peptide deformylase from Staphylococcus aureus in complex with actinonin, a naturally occurring antibacterial agent

21 January 2018

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N-alkyl urea hydroxamic acids as a new class of peptide deformylase inhibitors with antibacterial activity

21 January 2018

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Peptide deformylase inhibitors as antibacterial agents: identification of VRC3375, a proline-3-alkylsuccinyl hydroxamate derivative, by using an integrated combinatorial and medicinal chemistry approach

21 January 2018

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Pharmacokinetics in animals and humans of a first-in-class peptide deformylase inhibitor

21 January 2018

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Identification of an essential gene of Listeria monocytogenes involved in teichoic acid biogenesis

21 January 2018

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Teichoic acid is an essential polymer in Bacillus subtilis that is functionally distinct from teichuronic acid

21 January 2018

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Wall teichoic acid polymers are dispensable for cell viability in Bacillus subtilis

21 January 2018

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Lesions in teichoic acid biosynthesis in Staphylococcus aureus lead to a lethal gain of function in the otherwise dispensable pathway

21 January 2018

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DltABCD- and MprF-mediated cell envelope modifications of Staphylococcus aureus confer resistance to platelet microbicidal proteins and contribute to virulence in a rabbit endocarditis model.

21 January 2018

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Drugs for bad bugs: confronting the challenges of antibacterial discovery

21 January 2018

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Transcriptional regulation of the Staphylococcus aureus thioredoxin and thioredoxin reductase genes in response to oxygen and disulfide stress.

21 January 2018

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Molecular cloning and expression of the spsB gene encoding an essential type I signal peptidase from Staphylococcus aureus

21 January 2018

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ATP-binding cassette transporters are targets for the development of antibacterial vaccines and therapies

21 January 2018

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Cloning and functional characterization of an NAD(+)-dependent DNA ligase from Staphylococcus aureus

21 January 2018

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Identification of a novel essential two-component signal transduction system, YhcSR, in Staphylococcus aureus

21 January 2018

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Identification of an essential glycoprotease in Staphylococcus aureus.

21 January 2018

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Identification of genes controlled by the essential YycG/YycF two-component system of Staphylococcus aureus

21 January 2018

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Lipopeptide substrates for SpsB, the Staphylococcus aureus type I signal peptidase: design, conformation and conversion to α-ketoamide inhibitors

21 January 2018

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Discovery of a novel and potent class of FabI-directed antibacterial agents

21 January 2018

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Platensimycin is a selective FabF inhibitor with potent antibiotic properties

21 January 2018

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Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties

21 January 2018

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Identification of inhibitors of bacterial enoyl-acyl carrier protein reductase

21 January 2018

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Anchor structure of staphylococcal surface proteins. III. Role of the FemA, FemB, and FemX factors in anchoring surface proteins to the bacterial cell wall.

21 January 2018

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Structural insight into the transglycosylation step of bacterial cell-wall biosynthesis

21 January 2018

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Crystallization and preliminary X-ray analysis of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Staphylococcus aureus

21 January 2018

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21 January 2018

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Lipid II as a target for antibiotics

21 January 2018

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New class of bacterial phenylalanyl-tRNA synthetase inhibitors with high potency and broad-spectrum activity

21 January 2018

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21 January 2018

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Aminoacyl-tRNA synthetases: essential and still promising targets for new anti-infective agents

21 January 2018

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Emergence of resistance during mupirocin treatment: is it a problem in clinical practice?

21 January 2018

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Dual targeting of GyrB and ParE by a novel aminobenzimidazole class of antibacterial compounds

21 January 2018

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In vitro characterization of the antibacterial spectrum of novel bacterial type II topoisomerase inhibitors of the aminobenzimidazole class

21 January 2018

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Staphylococcal vaccines and immunotherapy: to dream the impossible dream?

21 January 2018

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Staphylococci in colonization and disease: prospective targets for drugs and vaccines

21 January 2018

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Surface protein adhesins of Staphylococcus aureus

21 January 2018

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Human immunoglobulin G recognizing fibrinogen-binding surface proteins is protective against both Staphylococcus aureus and Staphylococcus epidermidis infections in vivo

21 January 2018

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INH-A21: a donor-selected Staphylococcal human immune globulin for the prevention of late-onset neonatal Staphylococcal infection

21 January 2018

1 reference

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Development of StaphVAX, a polysaccharide conjugate vaccine against S. aureus infection: from the lab bench to phase III clinical trials

21 January 2018

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Identification of the capsular polysaccharides in Staphylococcus aureus clinical isolates by PCR and agglutination tests.

21 January 2018

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https://api.crossref.org/works/10.2217%2F17460913.2.6.655

Phase II, randomized, double-blind, multicenter study comparing the safety and pharmacokinetics of tefibazumab to placebo for treatment of Staphylococcus aureus bacteremia

21 January 2018

1 reference

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Open-label, dose escalation study of the safety and pharmacokinetic profile of tefibazumab in healthy volunteers

21 January 2018

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A humanized monoclonal antibody targeting Staphylococcus aureus

21 January 2018

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Identification of an immunodominant ABC transporter in methicillin-resistant Staphylococcus aureus infections

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.6.655

An immunogenicity study of a newly fusion protein Cna-FnBP vaccinated against Staphylococcus aureus infections in a mice model

21 January 2018

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https://api.crossref.org/works/10.2217%2F17460913.2.6.655

Immunization with Staphylococcus aureus clumping factor B, a major determinant in nasal carriage, reduces nasal colonization in a murine model

21 January 2018

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A novel Staphylococcus aureus vaccine: iron surface determinant B induces rapid antibody responses in rhesus macaques and specific increased survival in a murine S. aureus sepsis model

21 January 2018

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Vaccine assembly from surface proteins of Staphylococcus aureus.

21 January 2018

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Comparative opsonic and protective activities of Staphylococcus aureus conjugate vaccines containing native or deacetylated Staphylococcal Poly-N-acetyl-beta-(1-6)-glucosamine.

21 January 2018

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Trends in antimicrobial drug development: implications for the future

21 January 2018

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Why is big Pharma getting out of antibacterial drug discovery?

21 January 2018

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https://api.crossref.org/works/10.2217%2F17460913.2.6.655

Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.6.655

Conditional mutation of an essential putative glycoprotease eliminates autolysis in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.6.655

Dysregulation of bacterial proteolytic machinery by a new class of antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.6.655

Specific and potent inhibition of NAD+-dependent DNA ligase by pyridochromanones

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.6.655

Staphylococcus aureus capsular polysaccharides

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.6.655

Characterization of the opsonic and protective activity against Staphylococcus aureus of fully human monoclonal antibodies specific for the bacterial surface polysaccharide poly-N-acetylglucosamine

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.6.655

The role of fibronectin binding proteins in the pathogenesis of Staphylococcus aureus infections

21 January 2018

1 reference

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Understanding the mechanism of action of the exfoliative toxins of Staphylococcus aureus

21 January 2018

1 reference

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Toxic shock syndrome and bacterial superantigens: an update

21 January 2018

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Virulence determinants in Staphylococcus aureus and their involvement in clinical syndromes.

21 January 2018

1 reference

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Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.6.655

The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.6.655

Distribution of capsular and surface polysaccharide serotypes of Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.6.655

21 January 2018

Identifiers

DOI

10.2217/17460913.2.6.655

1 reference

17 September 2017

1 reference