(Q40170753)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17302910%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

p45, an ATPase subunit of the 19S proteasome, targets the polyglutamine disease protein ataxin-3 to the proteasome (English)

1 reference

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25 December 2019

8

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25 December 2019

author name string

Hongfeng Wang

1

1 reference

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25 December 2019

Nali Jia

2

1 reference

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25 December 2019

Erkang Fei

3

1 reference

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25 December 2019

Zhiming Wang

4

1 reference

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25 December 2019

Chao Liu

5

1 reference

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25 December 2019

Tao Zhang

6

1 reference

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25 December 2019

Jun Fan

7

1 reference

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25 December 2019

Lin Chen

9

1 reference

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25 December 2019

Nobuyuki Nukina

10

1 reference

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25 December 2019

Jiangning Zhou

11

1 reference

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25 December 2019

Guanghui Wang

12

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25 December 2019

language of work or name

English

0 references

publication date

14 February 2007

1 reference

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Journal of Neurochemistry

25 December 2019

published in

1 reference

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25 December 2019

volume

101

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25 December 2019

page(s)

1651-1661

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25 December 2019

issue

6

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Protein aggregation and the ubiquitin proteasome pathway: gaining the UPPer hand on neurodegeneration

25 December 2019

cites work

1 reference

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Defining the role of ubiquitin-interacting motifs in the polyglutamine disease protein, ataxin-3.

21 January 2018

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The polyglutamine neurodegenerative protein ataxin 3 regulates aggresome formation

21 January 2018

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The polyglutamine neurodegenerative protein ataxin-3 binds polyubiquitylated proteins and has ubiquitin protease activity

21 January 2018

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Evidence for proteasome involvement in polyglutamine disease: localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro

21 January 2018

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The association of epsin with ubiquitinated cargo along the endocytic pathway is negatively regulated by its interaction with clathrin

21 January 2018

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Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

21 January 2018

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Ataxin-3 interactions with rad23 and valosin-containing protein and its associations with ubiquitin chains and the proteasome are consistent with a role in ubiquitin-mediated proteolysis

21 January 2018

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Structure and Ubiquitin Binding of the Ubiquitin-interacting Motif

21 January 2018

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Multiubiquitin chain binding and protein degradation are mediated by distinct domains within the 26 S proteasome subunit Mcb1.

21 January 2018

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Functional analysis of the proteasome regulatory particle

21 January 2018

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A mutant ataxin-3 putative-cleavage fragment in brains of Machado-Joseph disease patients and transgenic mice is cytotoxic above a critical concentration.

21 January 2018

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Regulation of Membrane Protein Transport by Ubiquitin and Ubiquitin-Binding Proteins

21 January 2018

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Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

21 January 2018

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alpha-Synuclein affects the MAPK pathway and accelerates cell death

21 January 2018

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Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity

21 January 2018

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CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1

21 January 2018

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Polyglutamine diseases and molecular chaperones

21 January 2018

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Antigen processing by the proteasome

21 January 2018

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Ataxin-3 is a histone-binding protein with two independent transcriptional corepressor activities

21 January 2018

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Deubiquitinating function of ataxin-3: insights from the solution structure of the Josephin domain

21 January 2018

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Molecular clearance of ataxin-3 is regulated by a mammalian E4

21 January 2018

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CREB-binding protein sequestration by expanded polyglutamine

21 January 2018

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Analysis of the role of ubiquitin-interacting motifs in ubiquitin binding and ubiquitylation

21 January 2018

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Modulation of neurodegeneration by molecular chaperones

21 January 2018

1 reference

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The solution structure of the Josephin domain of ataxin-3: structural determinants for molecular recognition

21 January 2018

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Regional and cellular expression of the Machado-Joseph disease gene in brains of normal and affected individuals.

21 January 2018

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The multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover.

21 January 2018

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Machado-Joseph disease gene product is a cytoplasmic protein widely expressed in brain

21 January 2018

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Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3.

21 January 2018

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Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome

21 January 2018

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Elucidation of ataxin-3 and ataxin-7 function by integrative bioinformatics

21 January 2018

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Protein surveillance machinery in brains with spinocerebellar ataxia type 3: redistribution and differential recruitment of 26S proteasome subunits and chaperones to neuronal intranuclear inclusions

21 January 2018

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Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosis

21 January 2018

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Human Sug1/p45 is involved in the proteasome-dependent degradation of Sp1

21 January 2018

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Retro-translocation of proteins from the endoplasmic reticulum into the cytosol

21 January 2018

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The UIM domain of Hrs couples receptor sorting to vesicle formation

21 January 2018

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Multiubiquitin chain receptors define a layer of substrate selectivity in the ubiquitin-proteasome system

21 January 2018

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Machado-Joseph disease gene product identified in lymphocytes and brain.

21 January 2018

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Ataxin-3, the MJD1 gene product, interacts with the two human homologs of yeast DNA repair protein RAD23, HHR23A and HHR23B

21 January 2018

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Ataxin-3 suppresses polyglutamine neurodegeneration in Drosophila by a ubiquitin-associated mechanism.

21 January 2018

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Themes and variations on ubiquitylation

21 January 2018

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Characterization of two polyubiquitin binding sites in the 26 S protease subunit 5a

21 January 2018

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Structural and functional analysis of the Josephin domain of the polyglutamine protein ataxin-3

21 January 2018

1 reference

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