(Q40183754)

English

Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis

scientific article published on September 2007

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scholarly article

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Europe PubMed Central

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18 September 2017

Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis (English)

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Europe PubMed Central

PubMed publication ID

18 September 2017

primary biliary cholangitis

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detoxification enzyme

1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

6

object named as

Kurt Zatloukal

1 reference

Europe PubMed Central

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18 September 2017

Michael Trauner

8

object named as

Michael Trauner

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Europe PubMed Central

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18 September 2017

7

object named as

Helmut Denk

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Europe PubMed Central

PubMed publication ID

18 September 2017

author name string

Martin Wagner

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Europe PubMed Central

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18 September 2017

Peter Fickert

3

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Europe PubMed Central

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18 September 2017

Dagmar Silbert

4

1 reference

Europe PubMed Central

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18 September 2017

Judith Gumhold

5

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Europe PubMed Central

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18 September 2017

language of work or name

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based on heuristic

inferred from title

publication date

1 September 2007

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Europe PubMed Central

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18 September 2017

Liver International

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Europe PubMed Central

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18 September 2017

27

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Europe PubMed Central

PubMed publication ID

18 September 2017

7

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Europe PubMed Central

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18 September 2017

920-929

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Europe PubMed Central

PubMed publication ID

18 September 2017

Molecular pathogenesis of cholestasis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Role of nuclear receptors in the adaptive response to bile acids and cholestasis: pathogenetic and therapeutic considerations.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Molecular aspects of bile formation and cholestasis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Enterohepatic bile salt transporters in normal physiology and liver disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Hepatobiliary transporter expression in percutaneous liver biopsies of patients with cholestatic liver diseases.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Expression of hepatic transporters OATP-C and MRP2 in primary sclerosing cholangitis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Expression and localization of hepatobiliary transport proteins in progressive familial intrahepatic cholestasis

1 reference

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21 January 2018

Nuclear receptor regulation of hepatic function

1 reference

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21 January 2018

Induction of drug metabolism: the role of nuclear receptors.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Cellular regulation of hepatic bile acid transport in health and cholestasis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Combined loss of orphan receptors PXR and CAR heightens sensitivity to toxic bile acids in mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Chronic cholestatic diseases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Staging of chronic nonsuppurative destructive cholangitis (syndrome of primary biliary cirrhosis)

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

The simultaneous extraction of high-molecular-weight DNA and of RNA from solid tumors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Effects of ursodeoxycholic and cholic acid feeding on hepatocellular transporter expression in mouse liver

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

A domain-specific marker for the hepatocyte plasma membrane: localization of leucine aminopeptidase to the bile canalicular domain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Suppression of bile acid synthesis, but not of hepatic cholesterol 7alpha-hydroxylase expression, by obstructive cholestasis in humans

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Fxr(-/-) mice adapt to biliary obstruction by enhanced phase I detoxification and renal elimination of bile acids

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Molecular regulation of hepatobiliary transport systems: clinical implications for understanding and treating cholestasis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

The enzymes, regulation, and genetics of bile acid synthesis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Redundant pathways for negative feedback regulation of bile acid production

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Coordinated control of cholesterol catabolism to bile acids and of gluconeogenesis via a novel mechanism of transcription regulation linked to the fasted-to-fed cycle

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Cytokine patterns and cytotoxic mediators in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Regulation of cholesterol and bile acid homoeostasis in bile-obstructed rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Bile acid synthesis and biliary hydrophobicity during obstructive jaundice in rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Differences in the regulation of the classical and the alternative pathway for bile acid synthesis in human liver. No coordinate regulation of CYP7A1 and CYP27A1

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Transcriptional regulation of the human sterol 12alpha-hydroxylase gene (CYP8B1): roles of heaptocyte nuclear factor 4alpha in mediating bile acid repression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Alpha 1-fetoprotein transcription factor is required for the expression of sterol 12alpha -hydroxylase, the specific enzyme for cholic acid synthesis. Potential role in the bile acid-mediated regulation of gene transcription

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

UDP-Glucuronosyltransferases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Feed-forward regulation of bile acid detoxification by CYP3A4: studies in humanized transgenic mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Vitamin D receptor as an intestinal bile acid sensor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Regulation of CYP3A4 by the bile acid receptor FXR: evidence for functional binding sites in the CYP3A4 gene

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Protective role of hydroxysteroid sulfotransferase in lithocholic acid-induced liver toxicity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Dehydroepiandrosterone sulfotransferase gene induction by bile acid activated farnesoid X receptor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

FXR induces the UGT2B4 enzyme in hepatocytes: a potential mechanism of negative feedback control of FXR activity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Lithocholic acid decreases expression of UGT2B7 in Caco-2 cells: a potential role for a negative farnesoid X receptor response element

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Differential gene expression profiles in stage I primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4).

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Substrate specificity of human ABCC4 (MRP4)-mediated cotransport of bile acids and reduced glutathione

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

No relevant effect of ursodeoxycholic acid on cytochrome P450 3A metabolism in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Ursodeoxycholic acid-induced changes of plasma and urinary bile acids in patients with primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1478-3231.2007.01506.X

21 January 2018

Identifiers

10.1111/J.1478-3231.2007.01506.X

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

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