(Q40195901)

18 September 2017

High-resolution mapping identifies a commonly amplified 11q13.3 region containing multiple genes flanked by segmental duplications (English)

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18 September 2017

Johan H Gibcus

1

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18 September 2017

Klaas Kok

2

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18 September 2017

Lorian Menkema

3

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18 September 2017

Mario A Hermsen

4

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18 September 2017

Mirjam Mastik

5

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18 September 2017

Philip M Kluin

6

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18 September 2017

Jacqueline E van der Wal

7

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18 September 2017

Ed Schuuring

8

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18 September 2017

15 December 2006

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18 September 2017

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18 September 2017

121

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18 September 2017

187-201

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18 September 2017

2

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https://scigraph.springernature.com/pub.10.1007/s00439-006-0299-6

18 September 2017

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cites work

Short term cyclin D1 overexpression induces centrosome amplification, mitotic spindle abnormalities, and aneuploidy.

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00439-006-0299-6

Short inverted repeats initiate gene amplification through the formation of a large DNA palindrome in mammalian cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00439-006-0299-6

Molecular structure of double-minute chromosomes bearing amplified copies of the epidermal growth factor receptor gene in gliomas

21 January 2018

1 reference

12 December 2020

Concurrent activation of a novel putative transforming gene, myeov, and cyclin D1 in a subset of multiple myeloma cell lines with t(11;14)(q13;q32).

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12 December 2020

High-throughput analysis of subtelomeric chromosome rearrangements by use of array-based comparative genomic hybridization

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12 December 2020

Induction of multiple double-strand breaks within an hsr by meganucleaseI-SceI expression or fragile site activation leads to formation of double minutes and other chromosomal rearrangements

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12 December 2020

Amplification of oncogenes revisited: from expression profiling to clinical application

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12 December 2020

Translocations involving 6p22 in acute myeloid leukaemia at relapse: breakpoint characterization using microarray-based comparative genomic hybridization

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12 December 2020

Model for the formation of double minutes from prematurely condensed chromosomes of replicating micronuclei in drug-treated Chinese hamster ovary cells undergoing DNA amplification.

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12 December 2020

Genomic disorders: structural features of the genome can lead to DNA rearrangements and human disease traits

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12 December 2020

Comprehensive genome and transcriptome analysis of the 11q13 amplicon in human oral cancer and synteny to the 7F5 amplicon in murine oral carcinoma

1 reference

12 December 2020

The breakpoint region of the most common isochromosome, i(17q), in human neoplasia is characterized by a complex genomic architecture with large, palindromic, low-copy repeats

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12 December 2020

Mapping FRA11A, a folate-sensitive fragile site in human chromosome band 11q13.3.

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12 December 2020

Breakpoint identification and smoothing of array comparative genomic hybridization data

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12 December 2020

Gene amplification in cultured cells

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12 December 2020

Chromosome-wide assessment of replication timing for human chromosomes 11q and 21q: disease-related genes in timing-switch regions

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12 December 2020

Early dihydrofolate reductase gene amplification events in CHO cells usually occur on the same chromosome arm as the original locus

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12 December 2020

Replication timing of the human genome

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12 December 2020

The human genome browser at UCSC

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12 December 2020

Recurrent coamplification of cytoskeleton-associated genesEMS1 andSHANK2 withCCND1 in oral squamous cell carcinoma

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12 December 2020

Chromosomal instability and cytoskeletal defects in oral cancer cells

1 reference

12 December 2020

In vivo amplification of the PAX3-FKHR and PAX7-FKHR fusion genes in alveolar rhabdomyosarcoma

1 reference

12 December 2020

Array-based comparative genomic hybridization analysis identified cyclin D1 as a target oncogene at 11q13.3 in nasopharyngeal carcinoma

1 reference

12 December 2020

Fragile and unstable chromosomes in cancer: causes and consequences

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12 December 2020

Molecular-evolutionary mechanisms for genomic disorders

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12 December 2020

A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration

1 reference

12 December 2020

The involvement of the chromosome 11q13 region in human malignancies: cyclin D1 and EMS1 are two new candidate oncogenes--a review

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12 December 2020

Characterization of the EMS1 gene and its product, human Cortactin

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12 December 2020

Localization of the HST/FGFK gene with regard to 11q13 chromosomal breakpoint and fragile site

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12 December 2020

BAC microarray analysis of 15q11-q13 rearrangements and the impact of segmental duplications

1 reference

12 December 2020

Chromosomal fragile sites and DNA amplification in drug-resistant cells

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12 December 2020

Dysregulated cyclin D1 expression early in head and neck tumorigenesis: in vivo evidence for an association with subsequent gene amplification

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12 December 2020

Hotspots of mammalian chromosomal evolution

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12 December 2020

Initiation of the breakage-fusion-bridge mechanism through common fragile site activation in human breast cancer cells: the model of PIP gene duplication from a break at FRA7I

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12 December 2020

Variation in the expression of aphidicolin-induced fragile sites in human lymphocyte cultures

1 reference

12 December 2020

Amplification of the cyclin D1 gene is associated with tumour subsite, DNA non-diploidy and high S-phase fraction in squamous cell carcinoma of the head and neck

1 reference

12 December 2020

Direct duplication 12p11.21-p13.31 mediated by segmental duplications: a new recurrent rearrangement?

1 reference

12 December 2020

Co-amplified markers alternate in megabase long chromosomal inverted repeats and cluster independently in interphase nuclei at early steps of mammalian gene amplification

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12 December 2020

A region within murine chromosome 7F4, syntenic to the human 11q13 amplicon, is frequently amplified in 4NQO-induced oral cavity tumors.

1 reference

12 December 2020

Markers for assessment of nodal metastasis in laryngeal carcinoma

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12 December 2020

Centromeric breakage as a major cause of cytogenetic abnormalities in oral squamous cell carcinoma

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12 December 2020

High-resolution mapping of the 11q13 amplicon and identification of a gene, TAOS1, that is amplified and overexpressed in oral cancer cells.

1 reference

12 December 2020

Heterozygous submicroscopic inversions involving olfactory receptor-gene clusters mediate the recurrent t(4;8)(p16;p23) translocation

1 reference

12 December 2020

Assembly of microarrays for genome-wide measurement of DNA copy number

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12 December 2020

FISH characterization of head and neck carcinomas reveals that amplification of band 11q13 is associated with deletion of distal 11q

1 reference

12 December 2020

Application of a comprehensive subtelomere array in clinical diagnosis of mental retardation.

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12 December 2020

Translocation-excision-deletion-amplification mechanism leading to nonsyntenic coamplification of MYC and ATBF1.

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12 December 2020

A consistent pattern of RIN1 rearrangements in oral squamous cell carcinoma cell lines supports a breakage-fusion-bridge cycle model for 11q13 amplification

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12 December 2020

Serial segmental duplications during primate evolution result in complex human genome architecture

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12 December 2020

Delineation of the critical deletion region for congenital heart defects, on chromosome 8p23.1.

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12 December 2020

Complex Evolution of 7E Olfactory Receptor Genes in Segmental Duplications

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12 December 2020

The olfactory receptor universe--from whole genome analysis to structure and evolution.

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12 December 2020

The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements

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12 December 2020

Cyclin D1 amplification in chromosomal band 11q13 is associated with overrepresentation of 3q21-q29 in head and neck carcinomas

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12 December 2020

Replication of a common fragile site, FRA3B, occurs late in S phase and is delayed further upon induction: implications for the mechanism of fragile site induction

1 reference

12 December 2020

Enhanced flexibility and aphidicolin-induced DNA breaks near mammalian replication origins: implications for replicon mapping and chromosome fragility

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12 December 2020

Recent progress in understanding mechanisms of mammalian DNA amplification

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12 December 2020

Implications of human genome architecture for rearrangement-based disorders: the genomic basis of disease

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12 December 2020

Primate segmental duplications: crucibles of evolution, diversity and disease

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12 December 2020

Telomeres and the DNA damage response: why the fox is guarding the henhouse

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12 December 2020

Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification

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12 December 2020

The role of late/slow replication of the FRA16D in common fragile site induction

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12 December 2020

Chromosomal instability in oral cancer cells.

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12 December 2020

BCL6 alternative breakpoint region break and homozygous deletion of 17q24 in the nodular lymphocyte predominance type of Hodgkin's lymphoma-derived cell line DEV.

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12 December 2020

The role of DNA breaks in genomic instability and tumorigenesis

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12 December 2020

Gene amplification in cancer

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12 December 2020

Interstitial deletions and intrachromosomal amplification initiated from a double-strand break targeted to a mammalian chromosome

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12 December 2020

7E olfactory receptor gene clusters and evolutionary chromosome rearrangements

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12 December 2020

Amplification and overexpression of genes in 17p11.2 ~ p12 in osteosarcoma

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12 December 2020

Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons

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12 December 2020

Amplicons on human chromosome 11q are located in the early/late-switch regions of replication timing

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12 December 2020

New chromosomal regions with high-level amplifications in squamous cell carcinomas of the larynx and pharynx, identified by comparative genomic hybridization

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12 December 2020

EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer

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12 December 2020

Enrichment of segmental duplications in regions of breaks of synteny between the human and mouse genomes suggest their involvement in evolutionary rearrangements.

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12 December 2020

Oncogene amplification in solid tumors

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12 December 2020

Connecting chromosomes, crisis, and cancer

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12 December 2020

Direct visualization of dispersed 11q13 chromosomal translocations in mantle cell lymphoma by multicolor DNA fiber fluorescence in situ hybridization

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12 December 2020

DNA copy number gains in head and neck squamous cell carcinoma.

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12 December 2020

DNA microarrays for comparative genomic hybridization based on DOP-PCR amplification of BAC and PAC clones

1 reference

12 December 2020

The pattern of gene amplification is determined by the chromosomal location of hairpin-capped breaks

1 reference

12 December 2020

Assessment of chromosomal gains and losses in oral squamous cell carcinoma by comparative genomic hybridisation

1 reference

12 December 2020

Structure of a palindromic amplicon junction implicates microhomology-mediated end joining as a mechanism of sister chromatid fusion during gene amplification

1 reference

12 December 2020

10.1007/S00439-006-0299-6

Identifiers

DOI

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Dimensions Publication ID

18 September 2017

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