(Q40224466)

English

Analysis of Circulating Cell-Free DNA Identifies Multiclonal Heterogeneity of BRCA2 Reversion Mutations Associated with Resistance to PARP Inhibitors

scientific article published on 27 April 2017

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scholarly article

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Europe PubMed Central

PMC publication ID

4 March 2018

http://europepmc.org/abstract/PMC/5581695

Analysis of Circulating Cell-Free DNA Identifies Multiclonal Heterogeneity of BRCA2 Reversion Mutations Associated with Resistance to PARP Inhibitors (English)

1 reference

Europe PubMed Central

PMC publication ID

4 March 2018

http://europepmc.org/abstract/PMC/5581695

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Paul Lloyd

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Jacob Schwartzman

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Jacob Schwartzman

10

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Karen E Knudsen

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Karen Knudsen

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Christopher J Lord

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Christopher J Lord

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Alan Ashworth

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Europe PubMed Central

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4 March 2018

22

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Tomasz M Beer

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

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object named as

Eric J Small

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

author name string

David Quigley

1

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

Joshi J Alumkal

2

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Europe PubMed Central

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

Alexander W Wyatt

3

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Europe PubMed Central

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

Vishal Kothari

4

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Europe PubMed Central

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

Adam Foye

5

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Europe PubMed Central

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

Rahul Aggarwal

7

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Europe PubMed Central

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

Won Kim

8

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

Eric Lu

9

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Europe PubMed Central

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

Kevin Beja

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

Matti Annala

12

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

Rajdeep Das

13

1 reference

Europe PubMed Central

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

Morgan Diolaiti

14

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

Colin Pritchard

15

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Europe PubMed Central

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

George Thomas

16

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Europe PubMed Central

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

Scott Tomlins

17

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Europe PubMed Central

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

Charles Ryan

20

1 reference

Europe PubMed Central

PMC publication ID

4 March 2018

http://europepmc.org/abstract/PMC/5581695

Jack Youngren

21

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Europe PubMed Central

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

Felix Y Feng

25

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

publication date

27 April 2017

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Europe PubMed Central

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

Cancer Discovery

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Europe PubMed Central

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4 March 2018

http://europepmc.org/abstract/PMC/5581695

7

1 reference

Europe PubMed Central

PMC publication ID

4 March 2018

http://europepmc.org/abstract/PMC/5581695

9

1 reference

Europe PubMed Central

PMC publication ID

4 March 2018

http://europepmc.org/abstract/PMC/5581695

999-1005

1 reference

Europe PubMed Central

PMC publication ID

4 March 2018

http://europepmc.org/abstract/PMC/5581695

Laying a trap to kill cancer cells: PARP inhibitors and their mechanisms of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

15 June 2018

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

15 June 2018

DeconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

15 June 2018

BRCAness revisited

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

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Integrative clinical genomics of advanced prostate cancer

1 reference

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15 June 2018

Prediction and prioritization of rare oncogenic mutations in the cancer Kinome using novel features and multiple classifiers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

15 June 2018

Mechanisms of resistance to therapies targeting BRCA-mutant cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

15 June 2018

Signatures of mutational processes in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

15 June 2018

Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

15 June 2018

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

15 June 2018

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

15 June 2018

BEDTools: a flexible suite of utilities for comparing genomic features

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

15 June 2018

Pindel: a pattern growth approach to detect break points of large deletions and medium sized insertions from paired-end short reads

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

15 June 2018

The Sequence Alignment/Map format and SAMtools

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

15 June 2018

Fast and accurate short read alignment with Burrows-Wheeler transform

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

15 June 2018

Resistance to therapy caused by intragenic deletion in BRCA2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

15 June 2018

Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

15 June 2018

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

15 June 2018

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

15 June 2018

Cancer risks in BRCA2 mutation carriers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

15 June 2018

Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

17 June 2018

Reversion of BRCA1/2 Germline Mutations Detected in Circulating Tumor DNA From Patients With High-Grade Serous Ovarian Cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

20 August 2018

Prostate Cancer Progression and Survival in BRCA2 Mutation Carriers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5581695

2 December 2018

Identifiers

10.1158/2159-8290.CD-17-0146

1 reference

Europe PubMed Central

PMC publication ID

4 March 2018

http://europepmc.org/abstract/PMC/5581695

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 March 2018

http://europepmc.org/abstract/PMC/5581695

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 March 2018

http://europepmc.org/abstract/PMC/5581695

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