(Q40278164)

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Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells.

scientific article published on 22 March 2017

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scholarly article

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14 March 2020

Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells (English)

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14 March 2020

blood–brain barrier

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inferred from title

Katharina Günther

3

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14 March 2020

Frank Edenhofer

4

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14 March 2020

Winfried Neuhaus

9

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14 March 2020

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Heike Walles

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14 March 2020

author name string

Antje Appelt-Menzel

1

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14 March 2020

Alevtina Cubukova

2

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14 March 2020

Jörg Piontek

5

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14 March 2020

Gerd Krause

6

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14 March 2020

Tanja Stüber

7

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14 March 2020

Marco Metzger

10

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14 March 2020

publication date

23 March 2017

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14 March 2020

Stem Cell Reports

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14 March 2020

8

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14 March 2020

4

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14 March 2020

894-906

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14 March 2020

Generation of induced pluripotent stem cells from renal tubular cells of a patient with Alport syndrome

1 reference

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22 September 2017

Directed structural modification of Clostridium perfringens enterotoxin to enhance binding to claudin-5.

1 reference

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22 September 2017

In vitro porcine blood-brain barrier model for permeability studies: pCEL-X software pKa(FLUX) method for aqueous boundary layer correction and detailed data analysis.

1 reference

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22 September 2017

A stable and reproducible human blood-brain barrier model derived from hematopoietic stem cells

1 reference

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22 September 2017

Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Excision of viral reprogramming cassettes by Cre protein transduction enables rapid, robust and efficient derivation of transgene-free human induced pluripotent stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

iPS cell technologies: significance and applications to CNS regeneration and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Transport rankings of non-steroidal antiinflammatory drugs across blood-brain barrier in vitro models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Instruction of circulating endothelial progenitors in vitro towards specialized blood-brain barrier and arterial phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Comparative study of four immortalized human brain capillary endothelial cell lines, hCMEC/D3, hBMEC, TY10, and BB19, and optimization of culture conditions, for an in vitro blood-brain barrier model for drug permeability studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Efficient and rapid derivation of primitive neural stem cells and generation of brain subtype neurons from human pluripotent stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Modeling the blood-brain barrier using stem cell sources

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Complexity and developmental changes in the expression pattern of claudins at the blood-CSF barrier.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Blood-brain barrier in vitro models as tools in drug discovery: assessment of the transport ranking of antihistaminic drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Induced pluripotent stem cells--opportunities for disease modelling and drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Elucidating the principles of the molecular organization of heteropolymeric tight junction strands.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Neural stem cell systems: physiological players or in vitro entities?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Current in vitro and in silico models of blood-brain barrier penetration: a practical view.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Differential effects of hydrocortisone and TNFalpha on tight junction proteins in an in vitro model of the human blood-brain barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Induced pluripotent stem cell lines derived from human somatic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Modelling of the blood-brain barrier in drug discovery and development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Immortalized human brain endothelial cells and flow-based vascular modeling: a marriage of convenience for rational neurovascular studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Assessment of the first and second generation antihistamines brain penetration and role of P-glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Blood-brain barrier-specific properties of a human adult brain endothelial cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Permeability studies on in vitro blood-brain barrier models: physiology, pathology, and pharmacology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

The blood-brain barrier/neurovascular unit in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Manner of interaction of heterogeneous claudin species within and between tight junction strands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Modulation of tight junction structure in blood-brain barrier endothelial cells. Effects of tissue culture, second messengers and cocultured astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Electrical resistance across the blood-brain barrier in anaesthetized rats: a developmental study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5390136

22 September 2017

Oral bioavailability of P-glycoprotein substrate drugs do not differ between ABCB1-1Δ and ABCB1 wild type dogs

1 reference

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17 June 2018

Astrocytes and pericytes differentially modulate blood-brain barrier characteristics during development and hypoxic insult

1 reference

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17 June 2018

Relationship between permeability status of the blood-brain barrier and in vitro permeability coefficient of a drug

1 reference

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17 June 2018

Development of blood-brain barrier tight junctions in the rat cortex.

1 reference

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17 June 2018

Electrical resistance of brain microvascular endothelium.

1 reference

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1 reference

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1 reference

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20 August 2018

Closing the gap between the in-vivo and in-vitro blood-brain barrier tightness.

1 reference

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1 reference

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Neural precursor cell influences on blood-brain barrier characteristics in rat brain endothelial cells.

1 reference

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1 reference

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1 reference

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Correlation of tight junction morphology with the expression of tight junction proteins in blood-brain barrier endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/28344002

12 December 2020

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Identifiers

10.1016/J.STEMCR.2017.02.021

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28344002%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28344002%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28344002%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

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