(Q40284714)

19 September 2017

title

Re-expression of the tumor suppressor NF2/merlin inhibits invasiveness in mesothelioma cells and negatively regulates FAK. (English)

1 reference

19 September 2017

main subject

neoplastic invasiveness

1 reference

Poulikakos PI

1

1 reference

19 September 2017

Xiao GH

2

1 reference

19 September 2017

Gallagher R

3

1 reference

19 September 2017

Jablonski S

4

1 reference

19 September 2017

Jhanwar SC

5

1 reference

19 September 2017

Testa JR

6

1 reference

19 September 2017

language of work or name

English

0 references

publication date

1 May 2006

1 reference

19 September 2017

1 reference

19 September 2017

volume

25

1 reference

19 September 2017

issue

44

1 reference

19 September 2017

page(s)

5960-5968

1 reference

A mouse model recapitulating molecular features of human mesothelioma

19 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

High frequency of inactivating mutations in the neurofibromatosis type 2 gene (NF2) in primary malignant mesotheliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

ERM-Merlin and EBP50 protein families in plasma membrane organization and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

ERM proteins and merlin: integrators at the cell cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

The pathogenesis of mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Identification of Tyr-397 as the primary site of tyrosine phosphorylation and pp60src association in the focal adhesion kinase, pp125FAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Hemizygosity of Nf2 is associated with increased susceptibility to asbestos-induced peritoneal tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Tumour-cell invasion and migration: diversity and escape mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

FAK regulates biological processes important for the pathogenesis of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Differential regulation of cell motility and invasion by FAK

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

A NHERF binding site links the betaPDGFR to the cytoskeleton and regulates cell spreading and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Merlin phosphorylation by p21-activated kinase 2 and effects of phosphorylation on merlin localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Merlin, the Product of the Nf2 Tumor Suppressor Gene, Is an Inhibitor of the p21-Activated Kinase, Pak1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

NF2deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

The NF2 tumor suppressor Merlin and the ERM proteins interact with N-WASP and regulate its actin polymerization function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Clinical, cellular, and molecular aspects of cancer invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

The role of the CD44/ezrin complex in cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Membrane organization and tumorigenesis--the NF2 tumor suppressor, Merlin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

The role of focal-adhesion kinase in cancer - a new therapeutic opportunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Focal adhesion kinase: in command and control of cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Cell cycle-dependent nucleocytoplasmic shuttling of the neurofibromatosis 2 tumour suppressor merlin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Merlin/NF-2 mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Focal adhesion kinase: the first ten years

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Ezrin interacts with focal adhesion kinase and induces its activation independently of cell-matrix adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Analysis of current trends in United States mesothelioma incidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Mesothelioma trends in the United States: an update based on Surveillance, Epidemiology, and End Results Program data for 1973 through 2003.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Advances in malignant mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Serine 518 phosphorylation modulates merlin intramolecular association and binding to critical effectors important for NF2 growth suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Bombesin and platelet-derived growth factor induce association of endogenous focal adhesion kinase with Src in intact Swiss 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Multiple connections link FAK to cell motility and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Control of motile and invasive cell phenotypes by focal adhesion kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Src-dependent ezrin phosphorylation in adhesion-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Effect of merlin phosphorylation on neurofibromatosis 2 (NF2) gene function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Specific induction of pp125 focal adhesion kinase in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

p21-activated kinase links Rac/Cdc42 signaling to merlin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

Merlin: the neurofibromatosis 2 tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

inferred from DOI database lookup

7 January 2021

based on heuristic

A clue to the therapy of neurofibromatosis type 2: NF2/merlin is a PAK1 inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

inferred from DOI database lookup

7 January 2021

based on heuristic

Dysphagia research society 1998

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209587

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1209587

1 reference

Dimensions Publication ID

19 September 2017

1003751633

0 references

1 reference