(Q40400934)

20 September 2017

title

Quantitative single cell determination of ERK phosphorylation and regulation in relapsed and refractory primary acute myeloid leukemia (English)

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20 September 2017

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Ricciardi MR

1

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20 September 2017

McQueen T

2

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20 September 2017

Chism D

3

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20 September 2017

Milella M

4

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20 September 2017

Estey E

5

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20 September 2017

Kaldjian E

6

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20 September 2017

Sebolt-Leopold J

7

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20 September 2017

Konopleva M

8

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20 September 2017

Andreeff M

9

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20 September 2017

publication date

1 September 2005

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20 September 2017

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20 September 2017

volume

19

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20 September 2017

issue

9

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20 September 2017

page(s)

1543-1549

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Mechanisms of resistance to apoptosis in human AML blasts: the role of differentiation-induced perturbations of cell-cycle checkpoints.

20 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Amount of spontaneous apoptosis detected by Bax/Bcl-2 ratio predicts outcome in acute myeloid leukemia (AML).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Map kinase signaling pathways and hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Issues and progress with protein kinase inhibitors for cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Development of anticancer drugs targeting the MAP kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

CI-1040 (PD184352), a targeted signal transduction inhibitor of MEK (MAPKK)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Measurement of MAP kinase activation by flow cytometry using phospho-specific antibodies to MEK and ERK: potential for pharmacodynamic monitoring of signal transduction inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Intracellular phospho-protein staining techniques for flow cytometry: monitoring single cell signaling events

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Magnetic relaxation switches capable of sensing molecular interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Flow cytometric detection of total and serine 473 phosphorylated Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Single-cell analysis of signal transduction in CD4 T cells stimulated by antigen in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Kinetics of engraftment of CD34− and CD34+ cells from mobilized blood differs from that of CD34− and CD34+ cells from bone marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Gene expression profiling identifies significant differences between the molecular phenotypes of bone marrow-derived and circulating human CD34+ hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Sustained MAP kinase activation is required for the expression of cyclin D1, p21Cip1 and a subset of AP-1 proteins in CCL39 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Cell-cycle arrest by PD184352 requires inhibition of extracellular signal-regulated kinases (ERK) 1/2 but not ERK5/BMK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Survival of acute myeloid leukemia cells requires PI3 kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Inhibition of phosphatidylinositol 3-kinase dephosphorylates BAD and promotes apoptosis in myeloid leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Surprise phase III failure for ZD1839.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Requirement for the PI3K/Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Effects of the RAF/MEK/ERK and PI3K/AKT signal transduction pathways on the abrogation of cytokine-dependence and prevention of apoptosis in hematopoietic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Beyond single pathway inhibition: MEK inhibitors as a platform for the development of pharmacological combinations with synergistic anti-leukemic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

7 January 2021

Detection of intracellular phosphorylated STAT-1 by flow cytometry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

7 January 2021

An inhibitor of PI3-K differentially affects proliferation and IL-6 protein secretion in normal and leukemic myeloid cells depending on the stage of differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

7 January 2021

Functional and kinetic characterization of granulocyte colony-stimulating factor-primed CD34- human stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

7 January 2021

Constitutive activation of mitogen-activated protein kinase pathway in acute leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

7 January 2021

Downmodulation of ERK activity inhibits the proliferation and induces the apoptosis of primary acute myelogenous leukemia blasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

7 January 2021

Blockade of the extracellular signal-regulated kinase pathway induces marked G1 cell cycle arrest and apoptosis in tumor cells in which the pathway is constitutively activated: up-regulation of p27(Kip1)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403859

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2403859

1 reference

Dimensions Publication ID

20 September 2017

1037939927

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1 reference