(Q40416354)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15920462%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

title

Functional interactions of antiapoptotic proteins and tumor necrosis factor in the context of a replication-competent adenovirus (English)

1 reference

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12 January 2020

1 reference

1

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12 January 2020

author name string

Wang Y

2

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12 January 2020

Hallden G

3

1 reference

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12 January 2020

Brooks G

4

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12 January 2020

Francis J

5

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12 January 2020

Lemoine NR

6

1 reference

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12 January 2020

Kirn D

7

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12 January 2020

publication date

1 September 2005

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12 January 2020

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12 January 2020

volume

12

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12 January 2020

page(s)

1333-1346

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12 January 2020

issue

17

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3302555

12 January 2020

exact match

0 references

cites work

Replication-selective virotherapy for cancer: Biological principles, risk management and future directions

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Oncolytic biotherapy: a novel therapeutic plafform

21 January 2018

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Armed therapeutic viruses: strategies and challenges to arming oncolytic viruses with therapeutic genes

21 January 2018

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ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

21 January 2018

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Immunity to adenovirus and adeno-associated viral vectors: implications for gene therapy

21 January 2018

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Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015).

21 January 2018

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Immune responses to adenoviruses: viral evasion mechanisms and their implications for the clinic.

21 January 2018

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The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein

21 January 2018

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Interaction of E1B 19K with Bax is required to block Bax-induced loss of mitochondrial membrane potential and apoptosis

21 January 2018

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Epidermal growth factor receptor is down-regulated by a 10,400 MW protein encoded by the E3 region of adenovirus

21 January 2018

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Defective death receptor signaling as a cause of tumor immune escape

21 January 2018

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Apoptosis in cancer--implications for therapy

21 January 2018

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Multiple cell death pathways as regulators of tumour initiation and progression.

21 January 2018

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Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: what have we learned?

21 January 2018

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Evaluation of E1B gene-attenuated replicating adenoviruses for cancer gene therapy.

21 January 2018

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An E1B-19 kDa gene deletion mutant adenovirus demonstrates tumor necrosis factor-enhanced cancer selectivity and enhanced oncolytic potency

21 January 2018

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An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

21 January 2018

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A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.

21 January 2018

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Deletion of the adenoviral E1b-19kD gene enhances tumor cell killing of a replicating adenoviral vector

21 January 2018

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Novel immunocompetent murine tumor models for the assessment of replication-competent oncolytic adenovirus efficacy.

21 January 2018

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Infection of Mouse Liver by Human Adenovirus Type 5

21 January 2018

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Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity

21 January 2018

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Tumor necrosis factor alpha plays a central role in immune-mediated clearance of adenoviral vectors

21 January 2018

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E3 gene manipulations affect oncolytic adenovirus activity in immunocompetent tumor models

21 January 2018

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The dual effect of adenovirus type 5 E1A 13S protein on NF-kappaB activation is antagonized by E1B 19K.

21 January 2018

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Redundancy in tumor necrosis factor (TNF) and lymphotoxin (LT) signaling in vivo: mice with inactivation of the entire TNF/LT locus versus single-knockout mice

21 January 2018

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Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells

21 January 2018

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Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection

21 January 2018

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TNFalpha and IFNgamma induced by innate anti-adenoviral immune responses inhibit adenovirus-mediated transgene expression

21 January 2018

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7 January 2021

The adenovirus E3 10.4K and 14.5K proteins, which function to prevent cytolysis by tumor necrosis factor and to down-regulate the epidermal growth factor receptor, are localized in the plasma membrane

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7 January 2021

An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy

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7 January 2021

Wild-type adenovirus decreases tumor xenograft growth, but despite viral persistence complete tumor responses are rarely achieved--deletion of the viral E1b-19-kD gene increases the viral oncolytic effect

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302555

7 January 2021

Deletion of the gene encoding the adenovirus 5 early region 1b 21,000-molecular-weight polypeptide leads to degradation of viral and host cell DNA

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7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302555

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15920462%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 January 2020

0 references

1 reference