(Q40449526)

22 February 2018

title

Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth. (English)

1 reference

22 February 2018

33

John R Mascola

1 reference

22 February 2018

Elise Ishida

3

0 references

Mangaiarkarasi Asokan

Mangaiarkarasi Asokan

18

0 references

Garnett Kelsoe

26

Garnett Kelsoe

1 reference

22 February 2018

28

Barton F Haynes

1 reference

22 February 2018

34

Peter D Kwong

1 reference

22 February 2018

Tongqing Zhou

4

Tongqing Zhou

1 reference

22 February 2018

Nicole Doria-Rose

8

Nicole A Doria-Rose

1 reference

22 February 2018

M Gordon Joyce

17

M Gordon Joyce

1 reference

22 February 2018

Ivelin S. Georgiev

14

Ivelin S Georgiev

1 reference

22 February 2018

Mark K. Louder

23

Mark K Louder

1 reference

22 February 2018

Michael S Seaman

31

Michael S Seaman

1 reference

22 February 2018

Sijy O'Dell

11

Sijy O'Dell

1 reference

22 February 2018

Daniel C Douek

29

Daniel C Douek

1 reference

22 February 2018

Chaim A. Schramm

15

Chaim A Schramm

1 reference

22 February 2018

Amy Ransier

19

Amy Ransier

1 reference

22 February 2018

Aliaksandr Druz

13

Aliaksandr Druz

1 reference

22 February 2018

Sam Darko

20

Sam Darko

1 reference

22 February 2018

Zizhang Sheng

6

Zizhang Sheng

1 reference

22 February 2018

Krisha McKee

10

Krisha McKee

1 reference

22 February 2018

Jinghe Huang

1

Jinghe Huang

1 reference

22 February 2018

Stephen A Migueles

21

Stephen A Migueles

1 reference

22 February 2018

Munir Alam

24

S Munir Alam

1 reference

22 February 2018

Byong H Kang

2

Byong H Kang

1 reference

22 February 2018

Tarra Von Holle

27

Tarra Von Holle

1 reference

22 February 2018

author name string

Trevor Griesman

5

1 reference

22 February 2018

Fan Wu

7

1 reference

22 February 2018

Baoshan Zhang

9

1 reference

22 February 2018

Gwo-Yu Chuang

12

1 reference

22 February 2018

Anqi Zheng

16

1 reference

22 February 2018

Robert T Bailer

22

1 reference

22 February 2018

Robert Parks

25

1 reference

22 February 2018

Vanessa Hirsch

30

1 reference

22 February 2018

Lawrence Shapiro

32

1 reference

22 February 2018

Mark Connors

35

1 reference

22 February 2018

language of work or name

English

0 references

publication date

1 November 2016

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22 February 2018

published in

Immunity

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22 February 2018

volume

45

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22 February 2018

issue

5

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22 February 2018

page(s)

1108-1121

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22 February 2018

Determinants of HIV-1 broadly neutralizing antibody induction.

cites work

1 reference

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Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch

15 June 2018

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Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

15 June 2018

1 reference

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Broadly Neutralizing Antibodies for HIV Eradication

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

New approaches to HIV vaccine development

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site

15 June 2018

1 reference

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Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Antibody responses to envelope glycoproteins in HIV-1 infection

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Antibody engineering for increased potency, breadth and half-life

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

HIV-1 fitness cost associated with escape from the VRC01 class of CD4 binding site neutralizing antibodies

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Polyreactivity and autoreactivity among HIV-1 antibodies

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Rapid development of broadly influenza neutralizing antibodies through redundant mutations

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Isolation of human monoclonal antibodies from peripheral blood B cells

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Selection pressure on HIV-1 envelope by broadly neutralizing antibodies to the conserved CD4-binding site

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Increasing the potency and breadth of an HIV antibody by using structure-based rational design

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Mechanism of neutralization by the broadly neutralizing HIV-1 monoclonal antibody VRC01.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Glycosylation focuses sequence variation in the influenza A virus H1 hemagglutinin globular domain.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Role of N-linked glycans in the functions of hepatitis C virus envelope proteins incorporated into infectious virions

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Breadth of human immunodeficiency virus-specific neutralizing activity in sera: clustering analysis and association with clinical variables

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infection

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Structure of the Epstein-Barr virus major envelope glycoprotein

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Molecular evolution and circulation patterns of human respiratory syncytial virus subgroup a: positively selected sites in the attachment g glycoprotein

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Antibody neutralization and escape by HIV-1

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Rapid evolution of the neutralizing antibody response to HIV type 1 infection

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770152

10.1016/J.IMMUNI.2016.10.027

17 June 2018

Identifiers

DOI

1 reference

22 February 2018

PMCID

5770152

1 reference

22 February 2018

PubMed ID

27851912

1 reference

22 February 2018