(Q40484608)

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Induction of reactive oxygen species renders mutant and wild-type K-ras pancreatic carcinoma cells susceptible to Ad.mda-7-induced apoptosis

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Europe PubMed Central

PubMed publication ID

20 September 2017

Induction of reactive oxygen species renders mutant and wild-type K-ras pancreatic carcinoma cells susceptible to Ad.mda-7-induced apoptosis (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

apoptotic process

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reactive oxygen species

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pancreatic carcinoma

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5

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Samuel Waxman

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20 September 2017

7

object named as

Paul Dent

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20 September 2017

author name string

Irina V Lebedeva

1

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20 September 2017

Zao-Zhong Su

2

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20 September 2017

Devanand Sarkar

3

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20 September 2017

Rahul V Gopalkrishnan

4

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20 September 2017

Adly Yacoub

6

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20 September 2017

Paul B Fisher

8

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20 September 2017

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publication date

1 January 2005

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20 September 2017

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20 September 2017

24

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20 September 2017

4

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20 September 2017

585-596

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20 September 2017

Pancreatic cancer biology and genetics

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The roles of signaling by the p42/p44 mitogen-activated protein (MAP) kinase pathway; a potential route to radio- and chemo-sensitization of tumor cells resulting in the induction of apoptosis and loss of clonogenicity

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Stress and radiation-induced activation of multiple intracellular signaling pathways

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MAPK pathways in radiation responses

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Differentiation induction subtraction hybridization (DISH): a strategy for cloning genes displaying differential expression during growth arrest and terminal differentiation

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Identification and temporal expression pattern of genes modulated during irreversible growth arrest and terminal differentiation in human melanoma cells

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Focus on pancreas cancer

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RaSH, a rapid subtraction hybridization approach for identifying and cloning differentially expressed genes

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The melanoma differentiation associated gene mda-7 suppresses cancer cell growth

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An introduction to pancreatic adenocarcinoma genetics, pathology and therapy.

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Metastatic pancreatic cancer

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Bcl-2 and Bcl-x(L) differentially protect human prostate cancer cells from induction of apoptosis by melanoma differentiation associated gene-7, mda-7/IL-24.

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The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells

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Arsenic trioxide induces apoptosis in pancreatic cancer cells via changes in cell cycle, caspase activation, and GADD expression

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Mda-7, a novel melanoma differentiation associated gene with promise for cancer gene therapy

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The Medical Management of Pancreatic Cancer: A Review

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MDA-7 negatively regulates the beta-catenin and PI3K signaling pathways in breast and lung tumor cells

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Oncogenic Ras and Akt Signaling Contribute to Glioblastoma Formation by Differential Recruitment of Existing mRNAs to Polysomes

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Tumor-suppressive effects by adenovirus-mediated mda-7 gene transfer in non-small cell lung cancer cell in vitro

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mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK.

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Mechanistic aspects of mda-7/IL-24 cancer cell selectivity analysed via a bacterial fusion protein

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MDA-7/IL-24: novel cancer growth suppressing and apoptosis inducing cytokine

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PEG-3, a nontransforming cancer progression gene, is a positive regulator of cancer aggressiveness and angiogenesis

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Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner

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The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice

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Subtraction hybridization identifies a transformation progression-associated gene PEG-3 with sequence homology to a growth arrest and DNA damage-inducible gene

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Phase II trial of arsenic trioxide in patients with metastatic renal cell carcinoma

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Upregulation of GADD153 expression in the apoptotic signaling of N-(4-hydroxyphenyl)retinamide (4HPR).

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MDA-7 regulates cell growth and radiosensitivity in vitro of primary (non-established) human glioma cells

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mda-7(IL-24) Inhibits Growth and Enhances Radiosensitivity of Glioma Cells In Vitro via JNK Signaling

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N-(4-hydroxyphenyl)retinamide (4-HPR) modulates GADD45 expression in radiosensitive bladder cancer cell lines

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A combinatorial approach for selectively inducing programmed cell death in human pancreatic cancer cells

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7 January 2021

based on heuristic

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Mechanism of fenretinide (4-HPR)-induced cell death

1 reference

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based on heuristic

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10.1038/SJ.ONC.1208183

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

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