(Q40492449)

21 September 2017

title

The dileucine motif at the COOH terminus of human multidrug resistance P-glycoprotein is important for folding but not activity (English)

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21 September 2017

main subject

multiple drug resistance

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Tip W Loo

1

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21 September 2017

M Claire Bartlett

series ordinal

2

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21 September 2017

David M Clarke

series ordinal

3

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21 September 2017

language of work or name

English

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publication date

12 November 2004

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Journal of Biological Chemistry

21 September 2017

published in

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21 September 2017

volume

280

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21 September 2017

issue

4

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21 September 2017

page(s)

2522-2528

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Multidrug resistance in cancer: role of ATP-dependent transporters

21 September 2017

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Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

21 January 2018

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Familial persistent hyperinsulinemic hypoglycemia of infancy and mutations in the sulfonylurea receptor

21 January 2018

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Defective trafficking and function of KATP channels caused by a sulfonylurea receptor 1 mutation associated with persistent hyperinsulinemic hypoglycemia of infancy

21 January 2018

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21 January 2018

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Membrane topology of a cysteine-less mutant of human P-glycoprotein

21 January 2018

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Transmembrane organization of mouse P-glycoprotein determined by epitope insertion and immunofluorescence

21 January 2018

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The minimum functional unit of human P-glycoprotein appears to be a monomer.

21 January 2018

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The transmembrane domains of the human multidrug resistance P-glycoprotein are sufficient to mediate drug binding and trafficking to the cell surface.

21 January 2018

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Defining the drug-binding site in the human multidrug resistance P-glycoprotein using a methanethiosulfonate analog of verapamil, MTS-verapamil

21 January 2018

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Location of the rhodamine-binding site in the human multidrug resistance P-glycoprotein.

21 January 2018

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ATP hydrolysis cycles and mechanism in P-glycoprotein and CFTR.

21 January 2018

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Cystic fibrosis transmembrane conductance regulator has an altered structure when its maturation is inhibited

21 January 2018

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P-glycoprotein. Associations between domains and between domains and molecular chaperones

21 January 2018

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Introduction of the most common cystic fibrosis mutation (Delta F508) into human P-glycoprotein disrupts packing of the transmembrane segments.

21 January 2018

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Processing mutations located throughout the human multidrug resistance P-glycoprotein disrupt interactions between the nucleotide binding domains.

21 January 2018

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A PDZ-interacting domain in CFTR is an apical membrane polarization signal

21 January 2018

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The C terminus of SUR1 is required for trafficking of KATP channels

21 January 2018

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Rapid purification of human P-glycoprotein mutants expressed transiently in HEK 293 cells by nickel-chelate chromatography and characterization of their drug-stimulated ATPase activities.

21 January 2018

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21 January 2018

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The drug-binding pocket of the human multidrug resistance P-glycoprotein is accessible to the aqueous medium.

21 January 2018

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Superfolding of the partially unfolded core-glycosylated intermediate of human P-glycoprotein into the mature enzyme is promoted by substrate-induced transmembrane domain interactions.

21 January 2018

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Determining the dimensions of the drug-binding domain of human P-glycoprotein using thiol cross-linking compounds as molecular rulers

21 January 2018

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Site-specific recombination: developments and applications

21 January 2018

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Structure of MsbA from Vibrio cholera: a multidrug resistance ABC transporter homolog in a closed conformation

21 January 2018

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The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism

21 January 2018

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ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer

21 January 2018

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Cooperative, ATP-dependent association of the nucleotide binding cassettes during the catalytic cycle of ATP-binding cassette transporters

21 January 2018

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Identification and characterization of functionally important elements in the multidrug resistance protein 1 COOH-terminal region

21 January 2018

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Localization of sequences within the C-terminal domain of the cystic fibrosis transmembrane conductance regulator which impact maturation and stability

21 January 2018

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A C-terminal motif found in the beta2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteins

21 January 2018

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Accessory protein facilitated CFTR-CFTR interaction, a molecular mechanism to potentiate the chloride channel activity

21 January 2018

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A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression

21 January 2018

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PDZ domain interaction controls the endocytic recycling of the cystic fibrosis transmembrane conductance regulator

21 January 2018

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Increased diffusional mobility of CFTR at the plasma membrane after deletion of its C-terminal PDZ binding motif

21 January 2018

1 reference

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Identification and pharmacological correction of a membrane trafficking defect associated with a mutation in the sulfonylurea receptor causing familial hyperinsulinism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411483200

Sulfonylureas correct trafficking defects of ATP-sensitive potassium channels caused by mutations in the sulfonylurea receptor

21 January 2018

1 reference

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Identification of Residues within the Drug-binding Domain of the Human Multidrug Resistance P-glycoprotein by Cysteine-scanning Mutagenesis and Reaction with Dibromobimane

21 January 2018

1 reference

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Correction of Defective Protein Kinesis of Human P-glycoprotein Mutants by Substrates and Modulators

21 January 2018

1 reference

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Identification of Residues in the Drug-binding Domain of Human P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411483200

21 January 2018

Identifiers

DOI

10.1074/JBC.M411483200

1 reference

21 September 2017

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