(Q40724271)

English

Introduction of the most common cystic fibrosis mutation (Delta F508) into human P-glycoprotein disrupts packing of the transmembrane segments.

scientific article published on 17 June 2002

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12070134%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Introduction of the most common cystic fibrosis mutation (Delta F508) into human P-glycoprotein disrupts packing of the transmembrane segments (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12070134%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

cystic fibrosis

0 references

transmembrane protein

0 references

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12070134%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

author name string

M Claire Bartlett

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12070134%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

David M Clarke

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12070134%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

language of work or name

0 references

publication date

17 June 2002

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12070134%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12070134%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

277

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12070134%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

31

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12070134%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

27585-27588

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12070134%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Structure and function of the CFTR chloride channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Cystic fibrosis transmembrane conductance regulator. Structure and function of an epithelial chloride channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Cystic fibrosis transmembrane conductance regulator has an altered structure when its maturation is inhibited

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

ABC Transporters: From Microorganisms to Man

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Membrane topology of a cysteine-less mutant of human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Transmembrane organization of mouse P-glycoprotein determined by epitope insertion and immunofluorescence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

The transmembrane domains of the human multidrug resistance P-glycoprotein are sufficient to mediate drug binding and trafficking to the cell surface.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

The packing of the transmembrane segments of human multidrug resistance P-glycoprotein is revealed by disulfide cross-linking analysis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Rapid and efficient site-specific mutagenesis without phenotypic selection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

DNA sequencing with chain-terminating inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Crystal structure of the ATP-binding subunit of an ABC transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon Thermococcus litoralis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Crystal structures of the MJ1267 ATP binding cassette reveal an induced-fit effect at the ATPase active site of an ABC transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

The crystal structure of the MJ0796 ATP-binding cassette. Implications for the structural consequences of ATP hydrolysis in the active site of an ABC transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Frontiers in research on cystic fibrosis: understanding its molecular and chemical basis and relationship to the pathogenesis of the disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Relation between the turnover number for vinblastine transport and for vinblastine-stimulated ATP hydrolysis by human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Defining the drug-binding site in the human multidrug resistance P-glycoprotein using a methanethiosulfonate analog of verapamil, MTS-verapamil

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Cysteines 431 and 1074 are responsible for inhibitory disulfide cross-linking between the two nucleotide-binding sites in human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

P-glycoprotein. Associations between domains and between domains and molecular chaperones

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Vanadate trapping of nucleotide at the ATP-binding sites of human multidrug resistance P-glycoprotein exposes different residues to the drug-binding site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Glycerol reverses the misfolding phenotype of the most common cystic fibrosis mutation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Modeling of nucleotide binding domains of ABC transporter proteins based on a F1-ATPase/recA topology: structural model of the nucleotide binding domains of the cystic fibrosis transmembrane conductance regulator (CFTR)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Cystic fibrosis transmembrane conductance regulator: solution structures of peptides based on the Phe508 region, the most common site of disease-causing DeltaF508 mutation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Improvements in protein secondary structure prediction by an enhanced neural network

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Helix propensities of the amino acids measured in alanine-based peptides without helix-stabilizing side-chain interactions.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Determining the dimensions of the drug-binding domain of human P-glycoprotein using thiol cross-linking compounds as molecular rulers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Correction of Defective Protein Kinesis of Human P-glycoprotein Mutants by Substrates and Modulators

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Identification of Residues in the Drug-binding Domain of Human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Identification of Residues within the Drug-binding Domain of the Human Multidrug Resistance P-glycoprotein by Cysteine-scanning Mutagenesis and Reaction with Dibromobimane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Inhibition of Oxidative Cross-linking between Engineered Cysteine Residues at Positions 332 in Predicted Transmembrane Segments (TM) 6 and 975 in Predicted TM12 of Human P-glycoprotein by Drug Substrates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Identification of Residues in the Drug-binding Site of Human P-glycoprotein Using a Thiol-reactive Substrate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200330200

21 January 2018

Identifiers

10.1074/JBC.C200330200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12070134%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12070134%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q40724271&oldid=1505930188"