(Q40494075)

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DNA adduct formation by 7H-dibenzo[c,g]carbazole and its tissue- and organ-specific derivatives in Chinese hamster V79 cell lines stably expressing cytochrome P450 enzymes

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Europe PubMed Central

PubMed publication ID

21 September 2017

DNA adduct formation by 7H-dibenzo[c,g]carbazole and its tissue- and organ-specific derivatives in Chinese hamster V79 cell lines stably expressing cytochrome P450 enzymes (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

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Radim J Srám

2 references

ORCID Public Data File 2021

Europe PubMed Central

PubMed publication ID

21 September 2017

author name string

Alena Gábelová

1

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Blanka Binková

2

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Zuzana Valovicová

3

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

publication date

1 January 2004

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Environmental and Molecular Mutagenesis

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Europe PubMed Central

PubMed publication ID

21 September 2017

44

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

448-458

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Cancer risk from occupational and environmental exposure to polycyclic aromatic hydrocarbons

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Synthesis of depurinating DNA adducts formed by one-electron oxidation of 7H-dibenzo[c,g]carbazole and identification of these adducts after activation with rat liver microsomes

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One-electron oxidation is not a major route of metabolic activation and DNA binding for the carcinogen 7H-dibenzo[c,g]carbazole in vitro and in mouse liver and lung.

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N-hydroxyarylamines

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Cytochrome P450 oxidations in the generation of reactive electrophiles: epoxidation and related reactions

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V79 Chinese hamster cells express cytochrome P-450 activity after simultaneous exposure to polycyclic aromatic hydrocarbons and aminophylline

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Heterocyclic polycyclic aromatic hydrocarbon carcinogenesis: 7H-dibenzo[c,g]carbazole metabolism by microsomal enzymes from mouse and rat liver

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Ionization potentials and metabolic activations of carbazole and acridine derivatives.

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A metabolic activation mechanism of 7H-dibenzo[c,g]carbazole via o-quinone. Part 2: covalent adducts of 7H-dibenzo[c,g]carbazole-3,4-dione with nucleic acid bases and nucleosides

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Induction of micronuclei by 7H-dibenzo[c,g]carbazole and its tissue specific derivatives in Chinese hamster V79MZh1A1 cells

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Role of cytochrome P4501A1 in biotransformation of a tissue specific sarcomagen N-methyldibenzo[c,g]carbazole.

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Mutagenicity of 7H-dibenzo[c,g]carbazole and its tissue specific derivatives in genetically engineered Chinese hamster V79 cell lines stably expressing cytochrome P450.

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Organ-specific, carcinogenic dibenzo[c,g]carbazole derivatives: discriminative response in S. typhimurium TA100 mutagenesis modulated by subcellular fractions of mouse liver

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Tissue-specific differences in adduct formation by hepatocarcinogenic and sarcomatogenic derivatives of 7H-dibenzo[c,g]carbazole in mouse parenchymal and nonparenchymal liver cells

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Comparative mutagenicity of 7H-dibenzo[c,g]carbazole and two derivatives in MutaMouse liver and skin

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10.1002/EM.20073

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

ResearchGate publication ID

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