(Q40607843)

English

Stable gene silencing in human monocytic cell lines using lentiviral-delivered small interference RNA. Silencing of the p110alpha isoform of phosphoinositide 3-kinase reveals differential regulation of adherence induced by 1alpha,25-dihydroxycholeca

scientific article published on 12 December 2003

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scholarly article

1 reference

Europe PubMed Central

22 September 2017

Stable gene silencing in human monocytic cell lines using lentiviral-delivered small interference RNA. Silencing of the p110alpha isoform of phosphoinositide 3-kinase reveals differential regulation of adherence induced by 1alpha,25-dihydroxycholeca (English)

1 reference

Europe PubMed Central

22 September 2017

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author name string

Jimmy S Lee

1

1 reference

Europe PubMed Central

22 September 2017

Zakaria Hmama

2

1 reference

Europe PubMed Central

22 September 2017

Alice Mui

3

1 reference

Europe PubMed Central

22 September 2017

Neil E Reiner

4

1 reference

Europe PubMed Central

22 September 2017

language of work or name

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publication date

12 December 2003

1 reference

Europe PubMed Central

22 September 2017

number of pages

10

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

22 September 2017

279

1 reference

Europe PubMed Central

22 September 2017

10

1 reference

Europe PubMed Central

22 September 2017

9379-9388

1 reference

Europe PubMed Central

22 September 2017

Rapid retroviral infection of human haemopoietic cells of different lineages: efficient transfer in fresh T cells.

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Mammalian RNAi for the masses

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

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A system for stable expression of short interfering RNAs in mammalian cells

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A DNA vector-based RNAi technology to suppress gene expression in mammalian cells

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RNA interference

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siRNA-mediated gene silencing in vitro and in vivo.

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21 January 2018

RNA interference: the new somatic cell genetics?

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21 January 2018

A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA.

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Synthesis and function of 3-phosphorylated inositol lipids

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21 January 2018

Phosphatidylinositol 3-kinase-dependent activation of protein kinase C-zeta in bacterial lipopolysaccharide-treated human monocytes

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1alpha,25-dihydroxyvitamin D(3)-induced myeloid cell differentiation is regulated by a vitamin D receptor-phosphatidylinositol 3-kinase signaling complex

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Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells

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Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages

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Distinct roles for the p110alpha and hVPS34 phosphatidylinositol 3'-kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesis

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Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation

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Differential regulation of phosphoinositide 3-kinase adapter subunit variants by insulin in human skeletal muscle

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An oncogenic fusion product of the phosphatidylinositol 3-kinase p85beta subunit and HUMORF8, a putative deubiquitinating enzyme

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Cloning of human p55 gamma, a regulatory subunit of phosphatidylinositol 3-kinase, by a yeast two-hybrid library screen with the insulin-like growth factor-I receptor

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Vitamin D receptor as a drug discovery target

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Membrane receptors for vitamin D steroid hormones: potential new drug targets.

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Vitamin D as a cytokine and hematopoetic factor

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21 January 2018

All-trans and 9-cis retinoic acid enhance 1,25-dihydroxyvitamin D3-induced monocytic differentiation of U937 cells

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21 January 2018

Lipopolysaccharide (LPS) partial structures inhibit responses to LPS in a human macrophage cell line without inhibiting LPS uptake by a CD14-mediated pathway

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21 January 2018

1,25-Dihydroxyvitamin D3 maintains adherence of human monocytes and protects them from thermal injury

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21 January 2018

Neutrophil-mediated injury to endothelial cells. Enhancement by endotoxin and essential role of neutrophil elastase

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Protein kinase C zeta plays a central role in activation of the p42/44 mitogen-activated protein kinase by endotoxin in alveolar macrophages

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21 January 2018

Monocyte adherence induced by lipopolysaccharide involves CD14, LFA-1, and cytohesin-1. Regulation by Rho and phosphatidylinositol 3-kinase

1 reference

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21 January 2018

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

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Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector

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Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors

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Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector

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Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences

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21 January 2018

Gene therapy: the first decade

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21 January 2018

Adeno-associated virus type 2-mediated transduction of human monocyte-derived dendritic cells: implications for ex vivo immunotherapy

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Transduction and utility of the granulocyte-macrophage colony-stimulating factor gene into monocytes and dendritic cells by adeno-associated virus.

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Recombinant adeno-associated virus-mediated gene transfer into human leukemia cell lines

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Cloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmannin

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Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest

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Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase

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21 January 2018

Early embryonic lethality in mice deficient in the p110beta catalytic subunit of PI 3-kinase

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Essential, nonredundant role for the phosphoinositide 3-kinase p110delta in signaling by the B-cell receptor complex.

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21 January 2018

A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation

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Gene-targeting reveals physiological roles and complex regulation of the phosphoinositide 3-kinases

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Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival.

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The p85 regulatory subunit controls sequential activation of phosphoinositide 3-kinase by Tyr kinases and Ras.

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Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase.

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Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

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Impaired kit- but not FcepsilonRI-initiated mast cell activation in the absence of phosphoinositide 3-kinase p85alpha gene products.

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Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice

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RNA interference (RNA(i)) induction with various types of synthetic oligonucleotide duplexes in cultured human cells.

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The activity of siRNA in mammalian cells is related to structural target accessibility: a comparison with antisense oligonucleotides

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Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

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Comparison of the kinetic properties of the lipid- and protein-kinase activities of the p110alpha and p110beta catalytic subunits of class-Ia phosphoinositide 3-kinases

1 reference

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21 January 2018

p85/p110-type phosphatidylinositol kinase phosphorylates not only the D-3, but also the D-4 position of the inositol ring

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Update on biological actions of 1alpha,25(OH)2-vitamin D3 (rapid effects) and 24R,25(OH)2-vitamin D3.

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21 January 2018

Molecular tools for study of genomic and rapid signal transduction responses initiated by 1 alpha,25(OH)(2)-vitamin D(3).

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CR3: a general purpose adhesion-recognition receptor essential for innate immunity

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MAP-kinase dependent induction of monocytic procoagulant activity by beta2-integrins

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21 January 2018

Identifiers

10.1074/JBC.M310638200

1 reference

Europe PubMed Central

22 September 2017

1 reference

Europe PubMed Central

22 September 2017

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