(Q40625071)

22 September 2017

title

SH2-B is a positive regulator of nerve growth factor-mediated activation of the Akt/Forkhead pathway in PC12 cells (English)

1 reference

22 September 2017

SH2-B Is a Positive Regulator of Nerve Growth Factor-mediated Activation of the Akt/Forkhead Pathway in PC12 Cells (English)

1 reference

https://api.crossref.org/works/10.1074/JBC.M310040200

22 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M310040200

22 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M310040200

22 March 2024

author name string

Xiaohong Wang

1

1 reference

22 September 2017

Linyi Chen

2

1 reference

22 September 2017

James Herrington

4

1 reference

22 September 2017

Christin Carter-Su

5

1 reference

22 September 2017

Travis J. Maures

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14565960

22 March 2024

language of work or name

English

0 references

publication date

16 October 2003

1 reference

full work available at URL

22 September 2017

http://www.jbc.org/content/279/1/133.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14565960

https://api.elsevier.com/content/article/PII:S0021925818527976?httpAccept=text/xml

22 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M310040200

https://api.elsevier.com/content/article/PII:S0021925818527976?httpAccept=text/plain

22 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M310040200

https://syndication.highwire.org/content/doi/10.1074/jbc.M310040200

22 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M310040200

Journal of Biological Chemistry

22 March 2024

published in

1 reference

22 September 2017

volume

279

1 reference

22 September 2017

issue

1

1 reference

22 September 2017

page(s)

133-141

1 reference

Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor

22 September 2017

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Nerve growth factor and epidermal growth factor rescue PC12 cells from programmed cell death induced by etoposide: distinct modes of protection against cell death by growth factors and a protein-synthesis inhibitor

21 January 2018

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21 January 2018

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Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses

21 January 2018

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Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

21 January 2018

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The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: a potential role for cellular raf kinases in neuronal growth factor signal transduction

21 January 2018

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Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells.

21 January 2018

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Mapping of atypical protein kinase C within the nerve growth factor signaling cascade: relationship to differentiation and survival of PC12 cells

21 January 2018

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ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK

21 January 2018

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Raf and akt mediate distinct aspects of sensory axon growth

21 January 2018

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Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

21 January 2018

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

21 January 2018

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Inhibition of phosphatidylinositol 3-kinase activity blocks depolarization- and insulin-like growth factor I-mediated survival of cerebellar granule cells.

21 January 2018

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In sympathetic but not sensory neurones, phosphoinositide-3 kinase is important for NGF-dependent survival and the retrograde transport of 125I-betaNGF.

21 January 2018

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Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase.

21 January 2018

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Depolarization and neurotrophins converge on the phosphatidylinositol 3-kinase-Akt pathway to synergistically regulate neuronal survival

21 January 2018

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

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Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

21 January 2018

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Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

21 January 2018

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Forkhead transcription factors: new insights into protein kinase B (c-akt) signaling.

21 January 2018

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Negative regulation of the forkhead transcription factor FKHR by Akt.

21 January 2018

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Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway

21 January 2018

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

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The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change

21 January 2018

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

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NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

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Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

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Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling

21 January 2018

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

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Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration

21 January 2018

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The inhibition of phosphatidylinositol-3-kinase induces neurite retraction and activates GSK3.

21 January 2018

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Direct control of the Forkhead transcription factor AFX by protein kinase B

21 January 2018

1 reference

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Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma

21 January 2018

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Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)

21 January 2018

1 reference

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daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

21 January 2018

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The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

21 January 2018

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Insulin-like growth factor-1-induced phosphorylation of the forkhead family transcription factor FKHRL1 is mediated by Akt kinase in PC12 cells

21 January 2018

1 reference

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Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

21 January 2018

1 reference

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

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Regulation of the forkhead transcription factor FKHR, but not the PAX3-FKHR fusion protein, by the serine/threonine kinase Akt.

21 January 2018

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14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport

21 January 2018

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Identification and characterization of novel substrates of Trk receptors in developing neurons

21 January 2018

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PSM, an insulin-dependent, pro-rich, PH, SH2 domain containing partner of the insulin receptor

21 January 2018

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Platelet-derived growth factor (PDGF) stimulates the association of SH2-Bbeta with PDGF receptor and phosphorylation of SH2-Bbeta

21 January 2018

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PSM, a mediator of PDGF-BB-, IGF-I-, and insulin-stimulated mitogenesis

21 January 2018

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Insulin-like growth factor-I receptor and insulin receptor association with a Src homology-2 domain-containing putative adapter

21 January 2018

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Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling

21 January 2018

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The yeast tribrid system--genetic detection of trans-phosphorylated ITAM-SH2-interactions

21 January 2018

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Alternative splicing, gene localization, and binding of SH2-B to the insulin receptor kinase domain.

21 January 2018

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Four PSM/SH2-B alternative splice variants and their differential roles in mitogenesis

21 January 2018

1 reference

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Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310040200

Cloning and characterization of Lnk, a signal transduction protein that links T-cell receptor activation signal to phospholipase C gamma 1, Grb2, and phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310040200

SH2-B and APS are multimeric adapters that augment TrkA signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310040200

Glycogen synthase kinase-3 beta activity is critical for neuronal death caused by inhibiting phosphatidylinositol 3-kinase or Akt but not for death caused by nerve growth factor withdrawal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310040200

Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310040200

Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310040200

Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310040200

Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310040200

Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310040200

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310040200

SH2-B is required for nerve growth factor-induced neuronal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310040200

SH2-B, a membrane-associated adapter, is phosphorylated on multiple serines/threonines in response to nerve growth factor by kinases within the MEK/ERK cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310040200

Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms

21 January 2018

3

1 reference

https://api.crossref.org/works/10.1074/JBC.M310040200

Inhibition of drug-induced apoptosis by survival factors in PC12 cells

22 March 2024

5

1 reference

https://api.crossref.org/works/10.1074/JBC.M310040200

Peroxynitrite-induced cytotoxicity in PC12 cells: evidence for an apoptotic mechanism differentially modulated by neurotrophic factors

22 March 2024

7

1 reference

https://api.crossref.org/works/10.1074/JBC.M310040200

Nedd2 is required for apoptosis after trophic factor withdrawal, but not superoxide dismutase (SOD1) downregulation, in sympathetic neurons and PC12 cells

22 March 2024

8

1 reference

https://api.crossref.org/works/10.1074/JBC.M310040200

Mitochondrial membrane potential and nuclear changes in apoptosis caused by serum and nerve growth factor withdrawal: time course and modification by (-)-deprenyl.

22 March 2024

9

1 reference

https://api.crossref.org/works/10.1074/JBC.M310040200

Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

22 March 2024

21

1 reference

https://api.crossref.org/works/10.1074/JBC.M310040200

Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI 3-kinase in IGF-1 signaling.

22 March 2024

23

1 reference

https://api.crossref.org/works/10.1074/JBC.M310040200

Ras regulates sympathetic neuron survival by suppressing the p53-mediated cell death pathway

22 March 2024

27

1 reference

https://api.crossref.org/works/10.1074/JBC.M310040200

Mechanism of activation of protein kinase B by insulin and IGF-1

22 March 2024

32

1 reference

https://api.crossref.org/works/10.1074/JBC.M310040200

22 March 2024

Identifiers

1 reference

22 September 2017

1 reference