(Q40630934)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14513366%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

title

Status of p53 phosphorylation and function in sensitive and resistant human cancer models exposed to platinum-based DNA damaging agents (English)

1 reference

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19 December 2019

1 reference

1

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19 December 2019

5

Zahid H Siddik

1 reference

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19 December 2019

author name string

Masayuki Watanabe

series ordinal

2

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19 December 2019

Junichi Nakamura

series ordinal

3

1 reference

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19 December 2019

Abdul R Khokhar

series ordinal

4

1 reference

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19 December 2019

publication date

26 September 2003

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14513366%20AND%20SRC:MED&resulttype=core&format=json

Journal of Cancer Research and Clinical Oncology

19 December 2019

published in

1 reference

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19 December 2019

volume

129

1 reference

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19 December 2019

issue

12

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19 December 2019

page(s)

709-718

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https://scigraph.springernature.com/pub.10.1007/s00432-003-0480-4

19 December 2019

exact match

0 references

cites work

Cooperative phosphorylation at multiple sites is required to activate p53 in response to UV radiation

1 reference

12 December 2020

Activation of the p53 tumor suppressor protein

1 reference

12 December 2020

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

1 reference

12 December 2020

The phosphatidylinositol 3-kinase inhibitor wortmannin sensitizes murine fibroblasts and human tumor cells to radiation and blocks induction of p53 following DNA damage

1 reference

12 December 2020

ATM dependent apoptosis in the nervous system

1 reference

12 December 2020

Signaling to p53: breaking the MDM2-p53 circuit

1 reference

12 December 2020

Functional activation of p53 via phosphorylation following DNA damage by UV but not gamma radiation

1 reference

12 December 2020

Enhanced phosphorylation of p53 by ATM in response to DNA damage

1 reference

12 December 2020

Tumor suppressor genes

1 reference

12 December 2020

The p21(cip1/waf1) cyclin-dependent kinase inhibitor enhances the cytotoxic effect of cisplatin in human ovarian carcinoma cells

1 reference

12 December 2020

Cancer. p53, guardian of the genome

1 reference

12 December 2020

Cross-resistance to diverse drugs is associated with primary cisplatin resistance in ovarian cancer cell lines.

1 reference

12 December 2020

Cell cycle control and cancer

1 reference

12 December 2020

Cells lacking CIP1/WAF1 genes exhibit preferential sensitivity to cisplatin and nitrogen mustard

1 reference

12 December 2020

The biology of ovarian cancer

1 reference

12 December 2020

Comparative antitumor studies on platinum(II) and platinum(IV) complexes containing 1,2-diaminocyclohexane

1 reference

12 December 2020

The complexity of p53 modulation: emerging patterns from divergent signals

1 reference

12 December 2020

Independent pathways of p53 induction by cisplatin and X-rays in a cisplatin-resistant ovarian tumor cell line.

1 reference

12 December 2020

Role of p53 in the ability of 1,2-diaminocyclohexane-diacetato-dichloro-Pt(IV) to circumvent cisplatin resistance

1 reference

12 December 2020

Post-translational modifications and activation of p53 by genotoxic stresses

1 reference

12 December 2020

p53 gene status and chemosensitivity in ovarian cancer

1 reference

12 December 2020

Radiosensitization of human tumor cells by the phosphatidylinositol3-kinase inhibitors wortmannin and LY294002 correlates with inhibition of DNA-dependent protein kinase and prolonged G2-M delay

1 reference

12 December 2020

Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents

1 reference

12 December 2020

Regulation of p53 in response to DNA damage

1 reference

12 December 2020

Multisite phosphorylation and the integration of stress signals at p53.

1 reference

12 December 2020

Flameless atomic absorption spectrophotometric determination of platinum in tissues solubilized in hyamine hydroxide

1 reference

12 December 2020

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

1 reference

12 December 2020

DNA Damage Induces p53-dependent Down-regulation of hCHK1.

1 reference

12 December 2020

Paclitaxel (Taxol) in relapsed and refractory ovarian cancer: the UK and Eire experience.

1 reference

12 December 2020

Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline.

1 reference

12 December 2020

A role for ATR in the DNA damage-induced phosphorylation of p53

1 reference

12 December 2020

ATM associates with and phosphorylates p53: mapping the region of interaction

1 reference

12 December 2020

Expression of p53 in cisplatin-resistant ovarian cancer cell lines: modulation with the novel platinum analogue (1R, 2R-diaminocyclohexane)(trans-diacetato)(dichloro)-platinum(IV)

1 reference

12 December 2020

Participation of p53 protein in the cellular response to DNA damage

1 reference

12 December 2020

The phosphatidylinositol 3-kinase/AKT signal transduction pathway plays a critical role in the expression of p21WAF1/CIP1/SDI1 induced by cisplatin and paclitaxel

1 reference

12 December 2020

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

1 reference

12 December 2020

Adenovirus-mediated p21((WAF1/SDII/CIP1)) gene transfer induces apoptosis of human cervical cancer cell lines

1 reference

12 December 2020

Ultraviolet radiation, but not gamma radiation or etoposide-induced DNA damage, results in the phosphorylation of the murine p53 protein at serine-389

1 reference

12 December 2020

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

1 reference

12 December 2020

The cellular response to p53: the decision between life and death

1 reference

12 December 2020

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

1 reference

12 December 2020

Enhanced DNA repair as a mechanism of resistance to cis-diamminedichloroplatinum(II).

1 reference

12 December 2020

Ataxia-telangiectasia and cellular responses to DNA damage.

1 reference

12 December 2020

Increased platinum-DNA damage tolerance is associated with cisplatin resistance and cross-resistance to various chemotherapeutic agents in unrelated human ovarian cancer cell lines

1 reference

12 December 2020

Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

1 reference

12 December 2020

Resistance to platinum compounds: mechanisms and beyond

1 reference

12 December 2020

Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner

1 reference

12 December 2020

Covalent and noncovalent modifiers of the p53 protein

1 reference

12 December 2020

Cellular pharmacology of cisplatin: perspectives on mechanisms of acquired resistance

1 reference

12 December 2020

Comparative properties of five human ovarian adenocarcinoma cell lines.

1 reference

12 December 2020

Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen

1 reference

12 December 2020

High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis

1 reference

12 December 2020

The role of DNA mismatch repair in platinum drug resistance

1 reference

12 December 2020

10.1007/S00432-003-0480-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14513366%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

1 reference