(Q40645288)

22 September 2017

title

Grb2-independent recruitment of Gab1 requires the C-terminal lobe and structural integrity of the Met receptor kinase domain (English)

1 reference

22 September 2017

Lisa S Lock

1

1 reference

22 September 2017

Melanie M Frigault

series ordinal

2

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22 September 2017

Caroline Saucier

series ordinal

3

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22 September 2017

Morag Park

series ordinal

4

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22 September 2017

language of work or name

English

0 references

publication date

22 May 2003

1 reference

Journal of Biological Chemistry

22 September 2017

published in

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22 September 2017

volume

278

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22 September 2017

issue

32

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22 September 2017

page(s)

30083-30090

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A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling

22 September 2017

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The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase

21 January 2018

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The tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the met receptor tyrosine kinase

21 January 2018

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Association of the multisubstrate docking protein Gab1 with the hepatocyte growth factor receptor requires a functional Grb2 binding site involving tyrosine 1356.

21 January 2018

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Met-induced JNK activation is mediated by the adapter protein Crk and correlates with the Gab1 - Crk signaling complex formation

21 January 2018

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Sustained recruitment of phospholipase C-gamma to Gab1 is required for HGF-induced branching tubulogenesis

21 January 2018

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Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses

21 January 2018

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Crk synergizes with epidermal growth factor for epithelial invasion and morphogenesis and is required for the met morphogenic program

21 January 2018

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Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases

21 January 2018

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Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins

21 January 2018

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New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

21 January 2018

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Gene dosage-dependent functions for phosphotyrosine-Grb2 signaling during mammalian tissue morphogenesis

21 January 2018

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Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

21 January 2018

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Use of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasis

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Branching tubulogenesis but not scatter of madin-darby canine kidney cells requires a functional Grb2 binding site in the Met receptor tyrosine kinase

21 January 2018

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SH2 domains recognize specific phosphopeptide sequences

21 January 2018

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Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain

21 January 2018

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Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor

21 January 2018

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21 January 2018

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Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region

21 January 2018

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Interaction with the phosphotyrosine binding domain/phosphotyrosine interacting domain of SHC is required for the transforming activity of the FLT4/VEGFR3 receptor tyrosine kinase

21 January 2018

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Efficient cellular transformation by the Met oncoprotein requires a functional Grb2 binding site and correlates with phosphorylation of the Grb2-associated proteins, Cbl and Gab1.

21 January 2018

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A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

21 January 2018

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Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors

21 January 2018

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The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

21 January 2018

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21 January 2018

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Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor

21 January 2018

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Scatter factor/hepatocyte growth factor is essential for liver development

21 January 2018

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Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Conformational parameters for amino acids in helical, beta-sheet, and random coil regions calculated from proteins

21 January 2018

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21 January 2018

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Proline residues in transmembrane helices: structural or dynamic role?

21 January 2018

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Activated ERK2 interacts with and phosphorylates the docking protein GAB1.

21 January 2018

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Determination of Gab1 (Grb2-associated binder-1) interaction with insulin receptor-signaling molecules

21 January 2018

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Grb10 interacts differentially with the insulin receptor, insulin-like growth factor I receptor, and epidermal growth factor receptor via the Grb10 Src homology 2 (SH2) domain and a second novel domain located between the pleckstrin homology [...]

21 January 2018

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Identification of the rat adapter Grb14 as an inhibitor of insulin actions

21 January 2018

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Surfing the insulin signaling web

21 January 2018

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Tyr624 and Tyr628 in insulin receptor substrate-2 mediate its association with the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Protein Modeling by E-mail

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

A Peptide Representing the Carboxyl-terminal Tail of the Met Receptor Inhibits Kinase Activity and Invasive Growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

A conserved inositol phospholipid binding site within the pleckstrin homology domain of the Gab1 docking protein is required for epithelial morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Epitope Mapping by Label-Free Biomolecular Interaction Analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Flexible-geometry conformational energy maps for the amino acid residue preceding a proline

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Structure of the Tie2 RTK domain: self-inhibition by the nucleotide binding loop, activation loop, and C-terminal tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

21 January 2018

Identifiers

DOI

10.1074/JBC.M302675200

1 reference

22 September 2017

1 reference