(Q40645288)

22 September 2017

Grb2-independent recruitment of Gab1 requires the C-terminal lobe and structural integrity of the Met receptor kinase domain (English)

1 reference

22 September 2017

Lisa S Lock

1

1 reference

22 September 2017

Melanie M Frigault

series ordinal

2

1 reference

22 September 2017

Caroline Saucier

series ordinal

3

1 reference

22 September 2017

Morag Park

series ordinal

4

1 reference

22 September 2017

language of work or name

English

0 references

publication date

22 May 2003

1 reference

Journal of Biological Chemistry

22 September 2017

1 reference

22 September 2017

278

1 reference

22 September 2017

30083-30090

1 reference

22 September 2017

32

1 reference

A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

In vivo functional analysis of the daughter of sevenless protein in receptor tyrosine kinase signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Essential role of Gab1 for signaling by the c-Met receptor in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Role of Gab1 in heart, placenta, and skin development and growth factor- and cytokine-induced extracellular signal-regulated kinase mitogen-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

The tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the met receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Association of the multisubstrate docking protein Gab1 with the hepatocyte growth factor receptor requires a functional Grb2 binding site involving tyrosine 1356.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Met-induced JNK activation is mediated by the adapter protein Crk and correlates with the Gab1 - Crk signaling complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Sustained recruitment of phospholipase C-gamma to Gab1 is required for HGF-induced branching tubulogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Crk synergizes with epidermal growth factor for epithelial invasion and morphogenesis and is required for the met morphogenic program

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Gene dosage-dependent functions for phosphotyrosine-Grb2 signaling during mammalian tissue morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Use of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Profiling the global tyrosine phosphorylation state by Src homology 2 domain binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Alternative splicing generates isoforms of the met receptor tyrosine kinase which undergo differential processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

ProMod and Swiss-Model: Internet-based tools for automated comparative protein modelling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Branching tubulogenesis but not scatter of madin-darby canine kidney cells requires a functional Grb2 binding site in the Met receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

SH2 domains recognize specific phosphopeptide sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Interaction with the phosphotyrosine binding domain/phosphotyrosine interacting domain of SHC is required for the transforming activity of the FLT4/VEGFR3 receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Efficient cellular transformation by the Met oncoprotein requires a functional Grb2 binding site and correlates with phosphorylation of the Grb2-associated proteins, Cbl and Gab1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Active and inactive protein kinases: structural basis for regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Scatter factor/hepatocyte growth factor is essential for liver development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Prediction of protein secondary structure at better than 70% accuracy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Conservation and prediction of solvent accessibility in protein families

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

The PSIPRED protein structure prediction server

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Protein secondary structure prediction based on position-specific scoring matrices

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Conformational parameters for amino acids in helical, beta-sheet, and random coil regions calculated from proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Empirical Predictions of Protein Conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Proline residues in transmembrane helices: structural or dynamic role?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Activated ERK2 interacts with and phosphorylates the docking protein GAB1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Determination of Gab1 (Grb2-associated binder-1) interaction with insulin receptor-signaling molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Grb10 interacts differentially with the insulin receptor, insulin-like growth factor I receptor, and epidermal growth factor receptor via the Grb10 Src homology 2 (SH2) domain and a second novel domain located between the pleckstrin homology [...]

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Identification of the rat adapter Grb14 as an inhibitor of insulin actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Surfing the insulin signaling web

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Tyr624 and Tyr628 in insulin receptor substrate-2 mediate its association with the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Protein Modeling by E-mail

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

A Peptide Representing the Carboxyl-terminal Tail of the Met Receptor Inhibits Kinase Activity and Invasive Growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

A conserved inositol phospholipid binding site within the pleckstrin homology domain of the Gab1 docking protein is required for epithelial morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Epitope Mapping by Label-Free Biomolecular Interaction Analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Flexible-geometry conformational energy maps for the amino acid residue preceding a proline

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

Structure of the Tie2 RTK domain: self-inhibition by the nucleotide binding loop, activation loop, and C-terminal tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302675200

21 January 2018

Identifiers

DOI

10.1074/JBC.M302675200

1 reference

22 September 2017

1 reference