(Q40694903)

22 September 2017

Apocytochrome c blocks caspase-9 activation and Bax-induced apoptosis (English)

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22 September 2017

2

1 reference

22 September 2017

Angel G Martin

1

1 reference

PubMed ID

12393884

22 September 2017

language of work or name

English

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publication date

18 October 2002

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Journal of Biological Chemistry

22 September 2017

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22 September 2017

277

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22 September 2017

50834-50841

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22 September 2017

52

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22 September 2017

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Cellular stress response and apoptosis in cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Caspase-10 is an initiator caspase in death receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Caspase-9 and APAF-1 form an active holoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Regulation of apoptotic protease activating factor-1 oligomerization and apoptosis by the WD-40 repeat region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Importance of the redox state of cytochrome c during caspase activation in cytosolic extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Cytochrome c binding to Apaf-1: the effects of dATP and ionic strength

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

A mutational epitope for cytochrome C binding to the apoptosis protease activation factor-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Determinants of cytochrome c pro-apoptotic activity. The role of lysine 72 trimethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Negative regulation of the Apaf-1 apoptosome by Hsp70

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

IAP proteins: blocking the road to death's door

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Matrix detachment induces caspase-dependent cytochrome c release from mitochondria: inhibition by PKB/Akt but not Raf signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Akt regulates cell survival and apoptosis at a postmitochondrial level

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Post-cytochrome C protection from apoptosis conferred by a MAPK pathway in Xenopus egg extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Oncogene-dependent apoptosis in extracts from drug-resistant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Oncogene-dependent apoptosis is mediated by caspase-9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Bax directly induces release of cytochrome c from isolated mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

PUMA induces the rapid apoptosis of colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Apocytochrome c requires the TOM complex for translocation across the mitochondrial outer membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Boo, a novel negative regulator of cell death, interacts with Apaf-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Diva, a Bcl-2 homologue that binds directly to Apaf-1 and induces BH3-independent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Apoptosis in neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Apoptosis: a potential target for discovering novel therapies for cardiovascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Selective, reversible caspase-3 inhibitor is neuroprotective and reveals distinct pathways of cell death after neonatal hypoxic-ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

An AAV-derived Apaf-1 dominant negative inhibitor prevents MPTP toxicity as antiapoptotic gene therapy for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Expression and functional analysis of Apaf-1 isoforms. Extra Wd-40 repeat is required for cytochrome c binding and regulated activation of procaspase-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Selective inhibitors of apoptotic caspases: implications for novel therapeutic strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Bacterial expression of a mitochondrial cytochrome c. Trimethylation of lys72 in yeast iso-1-cytochrome c and the alkaline conformational transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

Regulation of apoptosis by BH3 domains in a cell-free system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209369200

21 January 2018

Identifiers

DOI

10.1074/JBC.M209369200

1 reference

22 September 2017

1 reference

PubMed ID

12393884