(Q40714695)

23 September 2017

Cell culture model for acetaminophen-induced hepatocyte death in vivo (English)

1 reference

23 September 2017

Robert H Pierce

1

1 reference

23 September 2017

Christopher C Franklin

2

1 reference

23 September 2017

Jean S Campbell

3

1 reference

23 September 2017

Robert P Tonge

4

1 reference

23 September 2017

Weichao Chen

5

1 reference

23 September 2017

Nelson Fausto

6

1 reference

23 September 2017

Sidney D Nelson

7

1 reference

23 September 2017

Sam A Bruschi

8

1 reference

23 September 2017

language of work or name

English

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publication date

1 August 2002

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23 September 2017

Biochemical Pharmacology

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23 September 2017

64

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23 September 2017

3

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23 September 2017

413-424

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SOME ANTIPYRETICS RELATED TO ASPIRIN AND PHENACETIN

23 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Paracetamol (acetaminophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Protein targets of xenobiotic reactive intermediates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Role of CYP1A2 in the hepatotoxicity of acetaminophen: investigations using Cyp1a2 null mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Oxidation of acetaminophen to its toxic quinone imine and nontoxic catechol metabolites by baculovirus-expressed and purified human cytochromes P450 2E1 and 2A6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Identification of the hepatic protein targets of reactive metabolites of acetaminophen in vivo in mice using two-dimensional gel electrophoresis and mass spectrometry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Effect of acetaminophen administration on hepatic glutathione compartmentation and mitochondrial energy metabolism in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Hepatotoxicity after 3'-hydroxyacetanilide administration to buthionine sulfoximine-pretreated mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Implication of alterations in intracellular calcium ion homoeostasis in the advent of paracetamol-induced cytotoxicity in primary mouse hepatocyte monolayer cultures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Acetaminophen hepatotoxicity in vivo is not accompanied by oxidant stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Acetaminophen toxicity. Opposite effects of two forms of glutathione peroxidase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Selective protein covalent binding and target organ toxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Enhanced acetaminophen hepatotoxicity in transgenic mice overexpressing BCL-2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Conditional expression of mitogen-activated protein kinase phosphatase-1, MKP-1, is cytoprotective against UV-induced apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Purification and characterization of a Z-Leu-Leu-Leu-MCA degrading protease expected to regulate neurite formation: a novel catalytic activity in proteasome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Establishment and characterization of differentiated, nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor alpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Ca2+ antagonists inhibit DNA fragmentation and toxic cell death induced by acetaminophen

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Analysis of ATF3, a transcription factor induced by physiological stresses and modulated by gadd153/Chop10

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

gadd153/Chop10, a potential target gene of the transcriptional repressor ATF3.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Resistance to DNA fragmentation and chromatin condensation in mice lacking the DNA fragmentation factor 45

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Different cleavage pattern for poly(ADP-ribose) polymerase during necrosis and apoptosis in HL-60 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Establishment of the transformants expressing human cytochrome P450 subtypes in HepG2, and their applications on drug metabolism and toxicology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Oxidation of acetaminophen to N-acetyl-p-aminobenzoquinone imine by human CYP3A4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Cell nucleus and DNA fragmentation are not required for apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

CAD/DFF40 nuclease is dispensable for high molecular weight DNA cleavage and stage I chromatin condensation in apoptosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Two distinct pathways leading to nuclear apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Inhibition of Fas receptor (CD95)-induced hepatic caspase activation and apoptosis by acetaminophen in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Depletion of hepatic glutathione prevents death receptor-dependent apoptotic and necrotic liver injury in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Rapid degradation of a large fraction of newly synthesized proteins by proteasomes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Involvement of the proteasome in the programmed cell death of NGF-deprived sympathetic neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Proteasomes play an essential role in thymocyte apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Mitochondrial proliferation and paradoxical membrane depolarization during terminal differentiation and apoptosis in a human colon carcinoma cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Negative regulation of the Apaf-1 apoptosome by Hsp70

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

How an inhibitor of the HIV-I protease modulates proteasome activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

Identification of hepatic protein targets of the reactive metabolites of the non-hepatotoxic regioisomer of acetaminophen, 3'-hydroxyacetanilide, in the mouse in vivo using two-dimensional gel electrophoresis and mass spectrometry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901180-2

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-2952(02)01180-2

1 reference

23 September 2017

1 reference