(Q40755785)

23 September 2017

title

Intracellular Abeta is increased by okadaic acid exposure in transfected neuronal and non-neuronal cell lines (English)

1 reference

23 September 2017

8

Sally A Frautschy

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23 September 2017

5

Douglas Galasko

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23 September 2017

Xiaoyan Sun

1

1 reference

23 September 2017

Gregory M Cole

2

1 reference

23 September 2017

Teresa Chu

3

1 reference

23 September 2017

Weiming Xia

4

1 reference

23 September 2017

Haruyasu Yamaguchi

6

1 reference

23 September 2017

Kentaro Tanemura

7

1 reference

23 September 2017

Akihiko Takashima

9

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23 September 2017

publication date

1 March 2002

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23 September 2017

published in

Neurobiology of Aging

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23 September 2017

volume

23

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23 September 2017

issue

2

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23 September 2017

page(s)

195-203

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Early senile plaques in Down's syndrome brains show a close relationship with cell bodies of neurons

23 September 2017

cites work

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7 January 2021

Paired helical filament-like phosphorylation of tau, deposition of beta/A4-amyloid and memory impairment in rat induced by chronic inhibition of phosphatase 1 and 2A

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7 January 2021

Phosphorylation of tau, Abeta-formation, and apoptosis after in vivo inhibition of PP-1 and PP-2A.

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7 January 2021

Apoptosis of human myeloid leukemia cells induced by an inhibitor of protein phosphatases (okadaic acid) is prevented by Bcl-2 and Bcl-X(L)

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7 January 2021

Beta-amyloid peptide secretion by a microglial cell line is induced by beta-amyloid-(25-35) and lipopolysaccharide

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https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

The protein phosphatase inhibitor okadaic acid induces morphological changes typical of apoptosis in mammalian cells

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https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

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https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide

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7 January 2021

Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor protein

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7 January 2021

Effect of chloroquine and leupeptin on intracellular accumulation of amyloid-beta (A beta) 1-42 peptide in a murine N9 microglial cell line

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7 January 2021

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation.

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https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Okadaic acid: a new probe for the study of cellular regulation

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7 January 2021

Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells

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7 January 2021

Amyloid beta peptide formation in cell-free preparations. Regulation by protein kinase C, calmodulin, and calcineurin.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Amyloid precursor protein secretion and beta A4 amyloid generation are not mutually exclusive

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7 January 2021

Rodent models of Alzheimer's disease: rat A beta infusion approaches to amyloid deposits

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7 January 2021

Intracellular production of beta A4 amyloid of Alzheimer's disease: modulation by phosphoramidon and lack of coupling to the secretion of the amyloid precursor protein

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7 January 2021

Inhibition of beta-amyloid production by activation of protein kinase C.

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7 January 2021

Down patients: extracellular preamyloid deposits precede neuritic degeneration and senile plaques.

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7 January 2021

Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells

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7 January 2021

Phosphatase activity toward abnormally phosphorylated tau: decrease in Alzheimer disease brain.

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7 January 2021

Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides

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https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

12-O-Tetradecanoylphorbol-13-acetate-induced dephosphorylation of protein kinase Calpha correlates with the presence of a membrane-associated protein phosphatase 2A heterotrimer

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Fibrillogenesis of Alzheimer Abeta peptides studied by fluorescence energy transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Enhancement of MTT, a tetrazolium salt, exocytosis by amyloid beta-protein and chloroquine in cultured rat astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Neuronal cell death in Alzheimer's disease correlates with apoE uptake and intracellular Abeta stabilization

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Increased production of 4 kDa amyloid beta peptide in serum deprived human primary neuron cultures: possible involvement of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Protein kinase C activation increases release of secreted amyloid precursor protein without decreasing Abeta production in human primary neuron cultures.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Intracellular accumulation of beta-amyloid in cells expressing the Swedish mutant amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Increased cytotoxicity of cadmium in fibroblasts lacking c-fos

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Selective increase in cellular A beta 42 is related to apoptosis but not necrosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Deposition of ?/A4 protein along neuronal plasma membranes in diffuse senile plaques

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Okadaic acid induces selective arrest of protein transport in the rough endoplasmic reticulum and prevents export into COPII-coated structures

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Regulation of recombinant PKC alpha activity by protein phosphatase 1 and protein phosphatase 2A.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

The expression of amyloid beta protein precursor protects nerve cells from beta-amyloid and glutamate toxicity and alters their interaction with the extracellular matrix

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Evidence for phosphorylation and oligomeric assembly of presenilin 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Translating cell biology into therapeutic advances in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Production of the Alzheimer amyloid beta protein by normal proteolytic processing

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Detection of a novel intraneuronal pool of insoluble amyloid beta protein that accumulates with time in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Intracellular and secreted Alzheimer beta-amyloid species are generated by distinct mechanisms in cultured hippocampal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Amyloids beta40 and beta42 are generated intracellularly in cultured human neurons and their secretion increases with maturation

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Human neurons derived from a teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular beta-amyloid or A4 peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Intracellular generation and accumulation of amyloid beta-peptide terminating at amino acid 42.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Enhanced production and oligomerization of the 42-residue amyloid beta-protein by Chinese hamster ovary cells stably expressing mutant presenilins

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Diffuse plaques associated with astroglial amyloid beta protein, possibly showing a disappearing stage of senile plaques.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Monoclonal antibody to the C-terminus of beta-amyloid.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

Mechanisms of neuronal degeneration in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2801%2900265-2

7 January 2021

10.1016/S0197-4580(01)00265-2

Identifiers

DOI

1 reference

23 September 2017

1 reference