(Q40765807)

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Accompanying protein alterations in malignant cells with a microtubule-polymerizing drug-resistance phenotype and a primary resistance mechanism.

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4 December 2019

Accompanying protein alterations in malignant cells with a microtubule-polymerizing drug-resistance phenotype and a primary resistance mechanism (English)

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4 December 2019

Paraskevi Giannakakou

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4 December 2019

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4 December 2019

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T Fojo

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4 December 2019

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M S Poruchynsky

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4 December 2019

Y Ward

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4 December 2019

J C Bulinski

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4 December 2019

W G Telford

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4 December 2019

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1 December 2001

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4 December 2019

Biochemical Pharmacology

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4 December 2019

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4 December 2019

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4 December 2019

1469-1480

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4 December 2019

p53, the cellular gatekeeper for growth and division

1 reference

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Biochemical, cellular, and pharmacological aspects of the multidrug transporter

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Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization

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Double identity for proteins of the Bcl-2 family

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A license to kill

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Cell suicide for beginners

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Mcl-1--just another antiapoptotic Bcl-2 Homolog?

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The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2

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7 January 2021

Microtubules and signal transduction

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Microtubules and actin filaments: dynamic targets for cancer chemotherapy

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The effect of antimicrotubule agents on signal transduction pathways of apoptosis: a review

1 reference

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Microtubule polymerization dynamics

1 reference

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7 January 2021

Morphogenetic properties of microtubules and mitotic spindle assembly

1 reference

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7 January 2021

Antimitotic natural products and their interactions with tubulin

1 reference

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7 January 2021

Stabilization and functional modulation of microtubules by microtubule-associated protein 4.

1 reference

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7 January 2021

Mutations at phosphorylation sites of Xenopus microtubule-associated protein 4 affect its microtubule-binding ability and chromosome movement during mitosis

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7 January 2021

MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption

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7 January 2021

A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells

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7 January 2021

Paclitaxel selects for mutant or pseudo-null p53 in drug resistance associated with tubulin mutations in human cancer.

1 reference

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7 January 2021

Inhibition of HIF-1- and wild-type p53-stimulated transcription by codon Arg175 p53 mutants with selective loss of functions

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7 January 2021

Inhibitors of transcription, proteasome inhibitors, and DNA-damaging drugs differentially affect feedback of p53 degradation

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7 January 2021

Cyclin B interaction with microtubule-associated protein 4 (MAP4) targets p34cdc2 kinase to microtubules and is a potential regulator of M-phase microtubule dynamics

1 reference

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7 January 2021

MAP4 is the in vivo substrate for CDC2 kinase in HeLa cells: identification of an M-phase specific and a cell cycle-independent phosphorylation site in MAP4.

1 reference

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7 January 2021

Xenopus interphase and mitotic microtubule-associated proteins differentially suppress microtubule dynamics in vitro

1 reference

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7 January 2021

BAX enhances paclitaxel-induced apoptosis through a p53-independent pathway

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7 January 2021

BAX protein expression and clinical outcome in epithelial ovarian cancer

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7 January 2021

MCL-1, a member of the BLC-2 family, is induced rapidly in response to signals for cell differentiation or death, but not to signals for cell proliferation

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7 January 2021

Induction of BCL2 family member MCL1 as an early response to DNA damage.

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7 January 2021

Evidence for the colonic origin of ovarian cancer cell line SW626.

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7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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7 January 2021

A new model for microtubule-associated protein (MAP)-induced microtubule assembly. The Pro-rich region of MAP4 promotes nucleation of microtubule assembly in vitro

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7 January 2021

Taxol suppresses dynamics of individual microtubules in living human tumor cells

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7 January 2021

Identifiers

10.1016/S0006-2952(01)00804-8

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11728383%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11728383%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

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