(Q40808389)

English

Phosphoinositide 3-kinase-dependent regulation of interleukin-3-induced proliferation: involvement of mitogen-activated protein kinases, SHP2 and Gab2.

scientific article published on 2 May 2001

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scholarly article

1 reference

Europe PubMed Central

23 September 2017

Phosphoinositide 3-kinase-dependent regulation of interleukin-3-induced proliferation: involvement of mitogen-activated protein kinases, SHP2 and Gab2. (English)

1 reference

Europe PubMed Central

23 September 2017

4

object named as

Melanie J. Welham

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author name string

Bridget L. Craddock

1

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Jennifer Hobbs

2

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Christine E. Edmead

3

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language of work or name

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publication date

2 May 2001

1 reference

Europe PubMed Central

23 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

23 September 2017

276

1 reference

Europe PubMed Central

23 September 2017

24274-24283

1 reference

Europe PubMed Central

23 September 2017

26

1 reference

Europe PubMed Central

23 September 2017

p21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

p110δ, a novel phosphoinositide 3-kinase in leukocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Signaling by distinct classes of phosphoinositide 3-kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

p110delta, a novel phosphatidylinositol 3-kinase catalytic subunit that associates with p85 and is expressed predominantly in leukocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

A function for phosphatidylinositol 3-kinase beta (p85alpha-p110beta) in fibroblasts during mitogenesis: requirement for insulin- and lysophosphatidic acid-mediated signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

New insights into the control of MAP kinase pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

An analysis of Mek1 signaling in cell proliferation and transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Activated MEK stimulates expression of AP-1 components independently of phosphatidylinositol 3-kinase (PI3-kinase) but requires a PI3-kinase signal To stimulate DNA synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Platelet-derived-growth-factor stimulation of the p42/p44 mitogen-activated protein kinase pathway in airway smooth muscle: role of pertussis-toxin-sensitive G-proteins, c-Src tyrosine kinases and phosphoinositide 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Involvement of phosphatidylinositol 3-kinase in NFAT activation in T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Inhibition of phosphatidylinositol 3-kinase activity by adenovirus-mediated gene transfer and its effect on insulin action

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Phosphatidylinositol 3-OH kinase activity is not required for activation of mitogen-activated protein kinase by cytokines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Wortmannin inhibits mitogen-activated protein kinase activation by platelet-activating factor through a mechanism independent of p85/p110-type phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Conditional inhibition of the mitogen-activated protein kinase cascade by wortmannin. Dependence on signal strength

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Nuclear export of MAP kinase (ERK) involves a MAP kinase kinase (MEK)-dependent active transport mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

SHP1 and SHP2 protein-tyrosine phosphatases associate with betac after interleukin-3-induced receptor tyrosine phosphorylation. Identification of potential binding sites and substrates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Shc associates with the IL-3 receptor β subunit, SHIP and Gab2 following IL-3 stimulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Characterization of two SHP-2-associated binding proteins and potential substrates in hematopoietic cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

A phosphatidylinositol 3-kinase-dependent pathway that differentially regulates c-Raf and A-Raf

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Cooperation of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways during granulocyte colony-stimulating factor-induced hemopoietic cell proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Inhibition of phosphoinositide 3-kinase impairs pre-commitment cell cycle traverse and prevents differentiation in erythroleukaemia cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Stem cell factor/c-kit up-regulates cyclin D3 and promotes cell cycle progression via the phosphoinositide 3-kinase/p70 S6 kinase pathway in spermatogonia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Multiple ras effector pathways contribute to G(1) cell cycle progression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Ras activity late in G1 phase required for p27kip1 downregulation, passage through the restriction point, and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Role of Gab1 in heart, placenta, and skin development and growth factor- and cytokine-induced extracellular signal-regulated kinase mitogen-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

A critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Phosphoinositide 3-kinases: a conserved family of signal transducers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Tec tyrosine kinase links the cytokine receptors to PI-3 kinase probably through JAK

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Inhibition of the Phosphoinositide 3-Kinase Pathway Induces a Senescence-like Arrest Mediated by p27Kip1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009098200

21 January 2018

Identifiers

10.1074/JBC.M009098200

1 reference

Europe PubMed Central

23 September 2017

1 reference

Europe PubMed Central

23 September 2017

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